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Exploring host-pathogen interactions and immunological mechanisms.

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News and Publications

Recent Publications

Opioid conversion in adults with cancer: MASCC-ASCO-AAHPM-HPNA-NICSO guideline.

Davis MP, Davies A, McPherson ML, Reddy AS, Paice JA, Roeland EJ, Walsh D, Mercadante S, Case AA, Arnold RM, Satomi E, Crawford G, Bruera E, Bohlke K, Ripamonti C.

Support Care Cancer. 2025 Mar 3;33(3):243. doi: 10.1007/s00520-025-09286-z.

Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains.

Rosas-Lemus M, Minasov G, Brunzelle JS, Taha TY, Lemak S, Yin S, Shuvalova L, Rosecrans J, Khanna K, Seifert HS, Savchenko A, Stogios PJ, Ott M, Satchell KJF.

Protein Sci. 2025 Mar;34(3):e70050. doi: 10.1002/pro.70050.

Natural compounds target the M23B zinc metallopeptidase Mpg to modulate Neisseria gonorrhoeae Type IV pilus expression.

Nicholson KR, Yin S, Edwards JL, Luan C-H, Seifert HS.

mBio. 2025 Feb 25:e0402724. doi: 10.1128/mbio.04027-24. Online ahead of print.

Structural analysis of extracellular ATP-independent chaperones of streptococcal species and protein substrate interactions.

Agbavor C, Torres M, Inniss NL, Latimer S, Minasov G, Shuvalova L, Wawrzak Z, Borek D, Otwinowski Z, Stogios PJ, Savchenko A, Anderson WF, Satchell KJF, Cahoon LA.

mSphere. 2025 Feb 25;10(2):e0107824. doi: 10.1128/msphere.01078-24. Epub 2025 Jan 29.

Effects of protein boosters on antibody responses.

Awakoaiye B, Dangi T, Penaloza-MacMaster P.

bioRxiv [Preprint]. 2025 Feb 11:2025.02.08.637239. doi: 10.1101/2025.02.08.637239.

What We Do

Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.

Research

We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response. 
EXPLORE OUR AREAS OF FOCUS

Education

Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
SEE TRAINING OPPORTUNITIES

Center for Structural Biology of Infectious Diseases

The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

VISIT THE CSBID SITE

Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.

VISIT BASIC SCIENCE ADMINISTRATION SITE

Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE Starzl Academy Site

Health Equity

Our vision is to make Northwestern, our communities, all communities, our lives and the world a better place — with everyone having the chance and responsibility for reaching their own pinnacle of health.

Visit the Office of Health Equity

MD students see patients as part of the Education-Centered Medical Home program.