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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office

SEPTEMBER 2024 NEWSLETTER

The newsletter of the Feinberg School of Medicine Research Office

Feinberg Receives Record Research Funding

Feinberg principal investigators secured $742.2 million dollars in research funding and awards during the 2023-24 fiscal year, which is a five percent increase over the previous year, and the largest amount in the school’s history.

Read this feature story

Research Day 2024 Celebrates Scientific Discovery and Advances

Feinberg students, staff, trainees and faculty gathered to celebrate scientific discovery and presented research posters and abstracts at Feinberg’s 18th annual Lewis Landsberg Research Day on Thursday, September 12.

Read the full story

Northwestern Receives $55 Million to Advance Health Research

The Northwestern University Clinical and Translational Sciences (NUCATS) Institute has received $55 million in National Institutes of Health (NIH) funding to accelerate development, evaluation and implementation of improved healthcare interventions.

Read about NUCATS

Register Now

Nemmers Prize Lecture

Nemmers Prize Recipient Jeffrey Gordon, MD, a distinguished university professor at Washington University in St. Louis, will discuss the microbiome-targeted therapies for childhood undernutrition on September 30.

RSVP for the lecture

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Faculty Profile

Understanding How Inflammation Contributes to Cardiovascular Disease

Matthew Feinstein, ’11 MD, ’17 MSc, is an associate professor of Medicine in the Division of Cardiology, of Preventive Medicine in the Division of Epidemiology, and of Pathology. He is also the director of Northwestern's Clinical and Translational Immunocardiology Program and director of medical student research at Feinberg.

Read more about his research

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Staff Profile

Supporting Women’s Health Research

Takelia Walker is an associate department administrator in the Department of Obstetrics and Gynecology at Feinberg. A lifelong Chicagoan, Walker was born and raised on the south side of Chicago and has been with Northwestern since 2008.

Read more about her work

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Student Profile

Studying the Genetic Drivers of Rare Developmental Disorders

Aishwarya Ramamurthy is a fifth-year student in the Driskill Graduate Program in Life Sciences (DGP). She works in the laboratory of Gemma Carvill, PhD, assistant professor in the Ken and Ruth Davee Department of Neurology Division of Epilepsy and Clinical Neurophysiology, where she studies the genetic drivers of rare developmental disorders.

Learn more about her research

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Campus Events

Tue
Sep 24

SQLIFTS Lecture Series - Lucy Luo, MASc - “Machine learning augments diagnosis of acute cellular rejection in lung transplant”

Chicago - 12:00 PM - 1:00 PM

Thu
Sep 26

BMG Seminar: Michael Pacold, MD, PhD, NYU Grossman School of Medicine

Chicago - 10:00 AM - 11:00 AM

Fri
Sep 27

"Mapping the landscape of social behavior" | Ugne Klibaite, Ph.D

Chicago - 12:00 PM - 1:00 PM

Sat
Sep 28

Northwestern Medicine 2024 Clinical Updates in Anesthesiology Conference

Chicago - 7:00 AM - 7:00 PM

Research in the News

New York Times, August 27
A Popular Weight Loss Drug Is Getting a Price Cut
Lindsay Allen, PhD, was featured.

Crain's Chicago Business, August 13 
Long COVID's Brain Fog Doesn't Lift For Years
Igor Koralnik, MD, was featured. 

FOX 32 Chicago, August 13 
Chicago's Lurie Children's Hospital Secures $12M to Study Antibiotic Use in Treating Pediatric Pneumonia
Todd Florin, MD, was featured. 

Check out More Media Coverage

NUCATS Corner

New Funding Available for Northwestern Faculty

The Northwestern University Clinical and Translational Sciences (NUCATS) Institute has released requests for applications for a pair of funding opportunities.

The Joseph & Dorothy Giddan Child Health Research Awards initiative is seeking proposals for highly innovative, lab-based basic or lab-based translational research projects that expand the knowledgebase in the field of child health. The maximum award is $200,000 over two years.

The Eisenberg Pilot Awards aim to support innovative projects that bridge the gap between research laboratories and the clinical introduction of new therapies or devices, ultimately benefiting patients. The maximum award is $25,000. Both awards have an application deadline of November 1. 

Review Funding Resources

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Sponsored Research

Health Equity and Access to Leverage Technology for Improved Diabetic Retinopathy Outcomes (HEAL-DR)

  • PI: Dustin French, PhD, professor of Ophthalmology and Medical Social Sciences
  • Sponsor: National Eye Institute

Read more about this project

Sponsored Research

Mosaic: RCT of a Digital Health Intervention Delivering Peer Support Narratives and Psychoeducation to English- and Spanish-Speaking Stem Cell Transplant Recipients

  • PI: Christine Rini, PhD, professor in the Department of Medical Social Sciences in the Divisions of Intervention Science and Implementation Science 
  • Sponsor: National Cancer Institute 

Read more about this project

Breakthroughs Podcast

Overcoming Hormone Therapy Resistance in Prostate Cancer with Sarki Abdulkadir, MD, PhD

In this episode, Sarki Abdulkadir, MD, PhD, shares how his team bucked the conventional notion that the MYC gene is “undruggable” and uncovered a handful of compounds that block MYC gene activity, making prostate cancer tumors sensitive to hormone therapy and opening up a potential new therapeutic target for treatment-resistant prostate cancer. 

Listen to the podcast episode

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New Faculty

Brandon Jutras, PhD, joined Feinberg in June 2024 as an associate professor of Microbiology-Immunology. Previously he was associate professor in the Department of Biochemistry and Fralin Life Sciences Institute at Virginia Tech. His research has focused on studying the biology and pathogenesis of spirochetes with an emphasis on the agents that cause Lyme disease and syphilis. Jutras earned his PhD in Microbiology from the College of Medicine at University of Kentucky, prior to being a Howard Hughes Medical Institute postdoctoral fellow at Yale University. His innovative diagnostic project was selected for a 2021 Emerging Leader Award. 

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Galter Library

Approaching Two Years of the NIH Data Management and Sharing (DMS) Policy

A wide range of local efforts have been implemented to support compliance with the DMS Policy. The Galter Library team held meetings throughout 2023 with departments and individuals to update them on the new requirements.

Read the full article

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High Impact Research

Li R, Shah PH, Stewart TF, Nam JK, Bivalacqua TJ, Lamm DL, Uchio EM, Geynisman DM, Jacob JM, Meeks JJ, Dickstein R, Pearce SM, Kang SH, Jung SI, Kamat AM, Burke JM, Keegan KA, Steinberg GD. Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial. Nature Medicine. August 2024; 30(8):2216-2223.

McElvaney OJ, McMahon GT. International Medical Graduates and the Physician Workforce. JAMA. 2024; 332(6):490-496.

Moreno-Domínguez A, Colinas O, Arias-Mayenco I, Cabeza JM, López-Ogayar JL, Chandel NS, Weissmann N, Sommer N, Pascual A, López-Barneo J. Hif1α-dependent mitochondrial acute O2 sensing and signaling to myocyte Ca2+ channels mediate arterial hypoxic vasodilation. Nature Communications. August 2024; 15(1):6649-6649.

Morschhauser F, Dahiya S, Palomba ML, Martin Garcia-Sancho A, Reguera Ortega JL, Kuruvilla J, Jäger U, Cartron G, Izutsu K, Dreyling M, Kahl B, Ghesquieres H, Ardeshna K, Goto H, Barbui AM, Abramson JS, Borchmann P, Fleury I, Mielke S, Skarbnik A, de Vos S, Kamdar M, Karmali R, Viardot A, Farazi T, Fasan O, Lymp J, Vedal M, Nishii R, Avilion A, Papuga J, Kumar J, Nastoupil LJ. Lisocabtagene maraleucel in follicular lymphoma: the phase 2 TRANSCEND FL study. Nature Medicine. August 2024; 30(8):2199-2207.

Review More Publications

Featured Core

Proteomics Core

The mission of Northwestern Proteomics is to develop new proteomics technologies; to apply them to timely questions in basic, translational and clinical research; to educate researchers throughout the Chicagoland area; and to communicate our research findings to the wider scientific community.

Services Offered

  • Protein identification
  • Protein quantitation by label-free and labeled techniques (SILAC and TMT)
  • Epiproteomic Histone Modification Panel
  • Post-translation modifications (PTMs) including phosphoproteomics
  • Top-down proteomics

Learn more about Proteomics

NIH News

Fiscal Year 2025 NIH Loan Repayment Program Cycle Is Open Until November 21, 2024

In fiscal year (FY) 2024, the NIH funded nearly three-quarters of NIH Loan Repayment Program (LRP) applications, an incredible success rate. With that momentum in mind, the NIH is excited to announce that applications for the FY 2025 cycle are now being accepted until November 21, 2024. Those interested are encouraged to apply.

The Extramural LRP was developed to recruit and retain highly qualified biomedical and behavioral researchers within the research workforce. It does this by offering to repay up to $100,000 of qualified educational debt in exchange for a two-year commitment to research. To be eligible, you must be a qualified health professional engaged in NIH-mission relevant research for at least 20 hours per week at a nonprofit or government institution.

Navigate NIH Grants Policies in FY2025 with Confidence Webinar Registration Now Open

Mark your calendar and join peers for the upcoming webinar, NIH Grants Policy Updates: FY2025 Edition, on October 17, 2024, from 1:00 to 2:00 p.m. ET. This live, virtual event is an invaluable opportunity for grant administrators, research compliance officers, and anyone involved with NIH grants to stay informed on the latest policy news. Expert presenters from the NIH Office of Extramural Research will cover crucial updates on grant policies, systems and resources, and discuss how these changes could affect your institution’s compliance processes. Attendees can submit questions during registration, which may be addressed during the live Q&A session. Ensure you and your team are prepared for the upcoming fiscal year.

Read the Latest from NIH

Funding Opportunities

Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 – Clinical Trial Optional)

  • Sponsor: NIH, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • Deadline: October 16
  • Upper amount: Direct costs for the two-year period may not exceed $275,000

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)

  • Sponsor: NIH, National Cancer Institute (NCI)
  • Deadline: October 16
  • Upper amount: Combined budget for direct costs for the two-year project period may not exceed $275,000

Transgender People: Immunity, Prevention and Treatment of HIV and STIs (R21 Clinical Trial Not Allowed)

  • Sponsor: NIH, National Institute of Allergy and Infectious Diseases (NIAID)
  • Deadline: December 7
  • Upper amount: Combined budget for direct costs for the two-year project period may not exceed $275,000

Thank You For Reading

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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office