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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office

NOVEMBER 2023 NEWSLETTER

The newsletter of the Feinberg School of Medicine Research Office

Feinberg Scientists Make New Discoveries at the Forefront of Food Allergy Research

More than 100 million people in the U.S. experience various types of allergies each year, and allergies are the sixth leading cause of chronic illness in the country, according to the Asthma and Allergy Foundation of America.  

Though treatments for allergies have historically been slow-going, recent research by Feinberg investigators has provided new hope for the future of allergy management.

Read this feature story

Helping Faculty Clearly Communicate Their Research and Expertise

Northwestern launches a new initiative with resources on how to speak and write for the public. A joint initiative, co-sponsored by the Office of the Provost and the Office of Global Marketing and Communications (OGMC), offers a series of in-person and virtual workshops throughout the academic year to help faculty speak and write about their work using lay-friendly, compelling language.

Read the full story

Faculty Profile

Propelling Equitable, Early-Life Identification and Prevention of Mental Health Risk

Lauren Wakschlag, PhD, is a professor of Medical Social Sciences, of Pediatrics and of Psychiatry and Behavioral Sciences. Wakschlag’s research pinpoints early developmental markers of mental health risk, which includes characterizing the phenotype of emergent mental health problems in early childhood and elucidating prenatal origins of these disease pathways.

Read more about her research

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Staff Profile

Providing Clinical and Research Nursing Support

Christina Coventry, RN, is a senior clinical research associate in the Division of Endocrinology, Metabolism and Molecular Medicine. She supports the research of Amisha Wallia, MD, associate professor of Medicine in the Division of Endocrinology and of Preventive Medicine in the Division of Epidemiology.

Read more about Coventry

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Student Profile

Investigating How Glial Cells Regulate the Central Nervous System

Kate DeMeulenaere is a third-year PhD student in the Driskill Graduate Program. She came to Northwestern to study how glial cells regulate the central nervous system in the laboratory of Murali Prakriya, PhD, the Magerstadt Professor of Pharmacology.

Learn more about her research

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Campus Events

Thu
Aug 08

Assessment of Incivility During Surgical Mortality and Morbidity Conference - TIME Lecture Series - FAME

Online - 12:00 PM - 1:00 PM

Fri
Aug 09

Neurology Department Grand Rounds: Thomas Bleck, MD

Chicago - 12:00 PM - 1:00 PM

Fri
Aug 16

Pepper Center Rounds

No Location - 12:00 PM - 1:00 PM

Wed
Aug 21

Did My Learners Learn: Basic Inferential Statistics in Med Ed | FAME - Education Scholarship Session

Online - 12:00 PM - 1:00 PM

Research in the News

The New York Times, October 25
It’s Covid Season. What Are the New Rules for Staying Safe?
Marc Sala, MD, was featured.

Chicago Crain’s Business, October 23
On the policy side, Illinois leaders prioritize child mental health
Audrey Brewer, MD, MPH, was featured.

NBC News, October 17
As the number of vaccines for pregnant women rises, so does vaccine hesitancy
Melissa Simon, MD, MPH, was featured.

 

Check out More Media Coverage

NUCATS Corner

One-Hour Consultations Enhance Competitiveness of Grant Submissions

The NUCATS Institute offers expert guidance to increase the competitiveness of grant submissions. If you are in the planning stages of an R, U, T or P-type award with significant scope of work and infrastructure needs, you may be eligible for a NUCATS Grant Development and Implementation Studio. These one-hour virtual consultations bring together investigators and leadership from NUCATS and our affiliates to identify relevant resources available to support and enhance the competitiveness of your grant submission.

Learn more on NUCATS website

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Sponsored Research

Title: Improving Diagnostic Safety through STeatosis Identification, Risk stratification, and Referral in the ED (STIRRED)

  • PI: Amy Kontrick, MD, associate professor of Emergency Medicine and Medical Education
  • Co-I: Danielle McCarthy, MD, MS, associate professor of Emergency Medicine and Vice Chair of Research in the Department of Emergency Medicine
  • Sponsor: Agency for Healthcare Research and Quality

Read more about this project

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Sponsored Research

Title: Microphysiological modeling of Endometriosis

  • PI: Ji-Yong Julie Kim, PhD, Susy Y. Hung Research Professor of Obstetrics and Gynecology (Reproductive Science in Medicine)
  • Co-I: Magdy Milady, MD, MS chief of Minimally Invasive Gynecologic Surgery in the Department of Obstetrics and Gynecology, Albert B. Gerbie, MD, Professor of Obstetrics and Gynecology
  • Co-I: Angel Alvarez, PhD, research assistant professor of Neurology in the Ken and Ruth Davee Department
  • Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development 

Read more about this project

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Breakthroughs Podcast

Advancing Transplant Science with Daniela Ladner, MD, MPH

Northwestern Medicine is dedicated to improving outcomes for patients who are in need of organ transplants. Daniela Ladner, MD, MPH, is leading research that sheds light on the barriers to transplantation as the founding director of the Northwestern University Transplant Outcomes Research Collaborative (NUTORC). She discusses the groundbreaking research that makes Northwestern a leader in organ transplantation.

Listen to the podcast episode

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New Faculty

Jessica Schleider, PhD, joined Feinberg as associate professor of Medical Social Sciences in September. She leads the Lab for Scalable Mental Health and is a leader in research on single-session interventions for youth mental health. Her professional mission is to build and disseminate scalable, evidence-based mental health solutions that bridge previously unfillable gaps in mental healthcare ecosystems worldwide. Previously, she was assistant professor at Stony Brook University. Schleider completed her PhD in Clinical Psychology at Harvard University in 2018, along with her doctoral internship in Clinical and Community Psychology at Yale School of Medicine. 
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Galter Library

Maintenance of Open Resources at Galter Library

As a step toward our commitment to providing inclusive educational materials, the Collection Management and Metadata Services (CMMS) department just completed a comprehensive project aimed at enhancing the accessibility of open resources in our online catalog. Read a Q&A to learn more about open resources at Galter.

Read the Q&A here

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High Impact Research

Wong YC, Jayaraj ND, Belton TB, Shum GC, Ball HE, Ren D, Tadenev ALD, Krainc D, Burgess RW, Menichella DM. Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(44):e2313010120.

Yap C, Rekowski J, Ursino M, Solovyeva O, Patel D, Dimairo M, Weir CJ, Chan AW, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell KR, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards DP, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, de Bono J. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ. 2023;383:e076386.

Yap C, Solovyeva O, de Bono J, Rekowski J, Patel D, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Hopewell S, Ursino M, Rantell KR, Calvert M, Lee S, Kightley A, Ashby D, Chan AW, Garrett-Mayer E, Isaacs JD, Golub R, Kholmanskikh O, Richards D, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, Dimairo M, Weir CJ. Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ. 2023;383:e076387.

Youngblood MW, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas. Nature Communications. 2023;14(1):6279.

Review More Publications

Featured Core

Outcomes Measurement and Survey Core

The Outcomes Measurement and Survey Core (OMSC) provides expertise on the best ways to measure outcomes derived by self-report, serves as a central resource for state-of-the-science instruments and measurement methods, and provides in-house research support services for translation, collection and analysis of outcomes and survey data.

Key services:

  • Research Design Consultation Services
  • Programming & Analysis Services
  • Research Operations Services

Get more information about OSMC

NIH News

Opportunity for Outstanding DEIA Mentors to Apply for Supplemental Funding

There is now the availability of administrative supplements that recognize the essential role of effective mentorship in developing future researchers and building a diverse scientific workforce. Through the reissue of a Notice of Special Interest (NOSI) led by the Chief Officer for Scientific Workforce Diversity office, NIH will award up to $18 million in FY24 contingent upon NIH funding. These institutional awards supplement the existing awards of program directors and principal investigators who engage in outstanding diversity, equity, inclusion and accessibility mentorship. Because such efforts may not be appropriately recognized or compensated, this NOSI aims to reach individuals with limited NIH support. All eligible investigators are encouraged to apply. Your mentorship efforts are critical to advancing cultures of inclusiveness excellence in the biomedical and behavioral research enterprise and deserve the recognition this award provides.

Announcing a Simplified Review Framework for NIH Research Project Grant Applications

The NIH is pleased to announce that a simplified review framework will be implemented for grant receipt deadlines of January 25, 2025 and beyond. The simplified framework is expected to better focus peer reviewers on the key questions needed to asses the scientific and technical merit of proposed research projects. Reviewers will consider three factors in determining the overall impact score to include importance of the research, rigor and feasibility and expertise and resources. The intent is simply to focus reviewers on the fundamental questions that the NIH has always asked them to address in reviewing grant applications for their scientific and technical merit, while minimizing the impact of reputational bias.

Read the Latest from NIH

Funding Opportunities

Simons Collaboration on the Global Brain Transition to Independence Award

  • Sponsor: Simons Collaboration on the Global Brain (SCGB)
  • Deadline: January 10
  • Upper amount: $600,000 over three years

Systems-Level Risk Detection and Interventions to Reduce Suicide, Ideation and Behaviors in Youth from Underserved Populations (R01 Clinical Trial Optional)

  • Sponsor: NIH
  • Deadline: January 20
  • Upper amount: $500,000 over five years
Computational Models of Influenza Immunity (U01 Clinical Trial Not Allowed)
  • Sponsor: NIH, National Institute of Allergy and Infectious Diseases (NIAID)
  • Deadline: January 27
  • Upper amount: Up to $750,000 per year for a max of five years

Understanding Chronic Conditions Understudied Among Women (R01 Clinical Trial Optional)

  • Sponsor: NIH, Office of Research on Women’s Health (ORWH), National Heart, Lung, and Blood Institute (NHLBI), National Institute on Aging (NIA), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Cancer Institute (NCI)
  • Deadline: June 20
  • Upper amount: Up to $350,000 per year for four years

More Resources

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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office