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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office

DECEMBER 2023 NEWSLETTER

The newsletter of the Feinberg School of Medicine Research Office

Evolving Telehealth Research and its Place in Healthcare Delivery

Since the COVID-19 pandemic thrust many providers into telehealth appointments, scientists have been asking questions about the benefits and concerns of telehealth. While telehealth was in use and gathering interest prior to the pandemic, the need for it accelerated during a time when people were encouraged to stay home. Learn more about the NIH-funded research that is studying telehealth for individuals with chronic conditions.

Read this feature story

Feinberg Investigators Recognized on 2023 ‘Highly-Cited’ List

Twelve Feinberg faculty members were named to the 2023 “Highly Cited Researchers” list, published by Clarivate Analytics. The annual list identifies investigators who have demonstrated significant influence in their field through the publication of highly-cited publications during the last decade. 

Read the full story

Faculty Profile

Utilizing Machine Learning to Improve Clinical Care and Scientific Research

Lee Cooper, PhD, is associate professor of Pathology and director of the Division of Computational Pathology. His research is dedicated to improving the accuracy, explainability and efficiency of machine learning solutions to problems like diagnosis, prognostication and treatment response prediction.

Read more about his research

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Staff Profile

Supporting and Mentoring Research Administration

Melanie Mkrdichian is the associate director of research administration in the Basic Science Administration at Feinberg. In her current role as associate director of research administration within the Basic Science Administration she leads a team of 18 research administrators and is committed to mentorship and training. 

Read more about her work

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Student Profile

Pursuing Translational Cancer Research

Jamie Nelly Guillen Magaña is a fourth-year PhD student in the Driskill Graduate Program. She is working in the laboratory of Leonidas Platanias, MD, PhD, to understand how modulation of the gene SLFN12 could serve as a therapeutic approach for acute myeloid leukemia. 

Learn more about her research

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Campus Events

Thu
Aug 08

Assessment of Incivility During Surgical Mortality and Morbidity Conference - TIME Lecture Series - FAME

Online - 12:00 PM - 1:00 PM

Fri
Aug 09

Neurology Department Grand Rounds: Thomas Bleck, MD

Chicago - 12:00 PM - 1:00 PM

Fri
Aug 16

Pepper Center Rounds

No Location - 12:00 PM - 1:00 PM

Wed
Aug 21

Did My Learners Learn: Basic Inferential Statistics in Med Ed | FAME - Education Scholarship Session

Online - 12:00 PM - 1:00 PM

Research in the News

How to Protect Your Lungs and Breathe Easier, Especially As You Age
The Washington Post
Scott Budinger, MD, was featured. 

Can Little Actions Bring Big Joy? Researchers Find ‘Micro-Acts’ Can Boost Well-being
NPR
Judith Moskowitz, PhD, MPH, was featured. 

Running vs. Walking: Which Is Better for Lasting Health?
The New York Times
Allison Zielinski, MD, was featured. 

Check out More Media Coverage

NUCATS Corner

Institute Relaunches Office Hours

If you are new to NUCATS, part of a well-established research team or somewhere in-between, please consider taking advantage of the Institute's monthly office hours. Join NUCATS Institute Senior Navigator Toddie Hays to learn more about the resources and services available to help facilitate and accelerate your clinical and translational research.

Schedule an Appointment

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Sponsored Research

Title: The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?

  • PI: Steven Schwulst, MD, associate professor of Surgery in the Division of Trauma and Critical Care 

  • Sponsor: National Institute of Neurological Disorders and Stroke

Read more about this project

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Sponsored Research

Title: The Role of Telehealth in Improving Access to and Costs of Unscheduled Care Among Lower-Income Individuals

  • PI: Lindsay Allen, PhD, assistant professor of Emergency Medicine 

  • Sponsor: Agency for Healthcare Research and Quality

Read more about this project

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Breakthroughs Podcast

How Mitochondria Inform Disease Discoveries with Navdeep Chandel, PhD

Pioneering research from Navdeep Chandel, PhD, over the last 20 years has proven mitochondria are major players in lung disease, cancer, brain disease and immune-related diseases. In this episode he discusses how his team’s recent findings could advance the design and implementation of new therapies.  

Listen to the podcast episode

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New Faculty

Justin Ryder, PhD, joined Feinberg in April as associate professor of Surgery and Pediatrics in the Division of Pediatric Surgery. He is also vice chair of research for the Department of Surgery at Lurie Children’s Hospital. His research interests are focused on understanding the biology underlying treatment response for pediatric obesity. The goal of his NIH-funded research is to expedite the translation of treatment from adults to children for the disease of obesity and improve short-term and long-term outcomes for youth with obesity. His work spans the continuum of treatment with studies focused on lifestyle modification, medication and surgery. 
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Galter Library

Conducting Systematic and Scoping Reviews

Systematic reviews and scoping reviews offer comprehensive insights into existing literature or evidence on a specific topic. At the heart of these reviews lies a structured search process. Get insight from a Galter librarian on how to conduct these reviews and join upcoming classes.

Read the full article

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High Impact Research

Azcorra M, Gaertner Z, Davidson C, He Q, Kim H, Nagappan S, Hayes CK, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Longnecker R, Awatramani R, Dombeck DA. Unique functional responses differentially map onto genetic subtypes of dopamine neurons. Nature Neuroscience. 2023;26(10):1762-1774.

Blinder VS, Deal AM, Ginos B, Jansen J, Dueck AC, Mazza GL, Henson S, Carr P, Rogak LJ, Weiss A, Rapperport A, Jonsson M, Spears PA, Cella D, Gany F, Schrag D, Basch E. Financial Toxicity Monitoring in a Randomized Controlled Trial of Patient-Reported Outcomes During Cancer Treatment (Alliance AFT-39). Journal of Clinical Oncology. 2023;41(29):4652.

Bramante CT, Buse JB, Liebovitz DM, Nicklas JM, Puskarich MA, Cohen K, Belani HK, Anderson BJ, Huling JD, Tignanelli CJ, Thompson JL, Pullen M, Wirtz EL, Siegel LK, Proper JL, Odde DJ, Klatt NR, Sherwood NE, Lindberg SM, Karger AB, Beckman KB, Erickson SM, Fenno SL, Hartman KM, Rose MR, Mehta T, Patel B, Griffiths G, Bhat NS, Murray TA, Boulware DR. Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial. Lancet Infectious Diseases. 2023;23(10):1119-1129.

Cao Y, Liu H, Lu SS, Jones KA, Govind AP, Jeyifous O, Simmons CQ, Tabatabaei N, Green WN, Holder JL, Jr., Tahmasebi S, George AL, Jr., Dickinson BC. RNA-based translation activators for targeted gene upregulation. Nature Communications. 2023;14(1):6827.

Review More Publications

Featured Core

Transgenic and Targeted Mutagenesis Laboratory

The Transgenic and Targeted Mutagenesis Laboratory (TTML) is a shared resource designed to produce genetically engineered mice for our investigators.

Key services:

  • CRISPR/Cas9 Gene Editing
  • Transgenic Projects
  • Gene Targeting
  • ES Cell Injection
  • Importing Mouse Lines and Rederivation
  • Cryopreservation of Mouse Lines
  • Cryorecovery of Mouse Lines

Get more information about TTML

NIH News

New NIH Director: Monica Bertagnolli, MD

Monica M. Bertagnolli, MD, started November 9 as the 17th director of the National Institutes of Health, the nation’s biomedical research agency and largest public funder of biomedical research in the world. She is the first surgeon and second woman to hold the position. Nominated by President Biden, Bertagnolli was confirmed on a bipartisan basis by the U.S. Senate on November 7. Growing up in rural Wyoming, Bertagnolli experienced and saw firsthand the challenges faced by rural communities to access medical care and participate in medical research. Due to that lived experience, equity is a core value that drives all her efforts, which includes ensuring NIH research is equitable and accessible to all people from all walks of life regardless of income or zip code. Prior to serving as NIH director, Bertagnolli was a cancer surgeon for over 45 years. She was elected to the National Academy of Medicine in 2021.

You Are Invited to Participate in a Pilot of Data Management and Sharing Plan Templates

The Federal Demonstration Partnership (FDP) is an association of federal agencies, research policy organizations and academic research institutions with the mission of streamlining the administration of federally-sponsored research and create resources that are available to the research enterprise. NIH has worked closely with them to implement their Data Management and Sharing (DMS) Policy that went into effect in January 2023. They are seeking feedback on two different templates that will assist in the DMS Plan. These templates are available on the FDP website to try. They encourage researchers to use the alpha and bravo template versions when preparing DMS plans, and submit the FDP survey with feedback on their experience.

Read the Latest from NIH

Funding Opportunities

Alzheimer’s Drug-Development Program (U01 Clinical Trial Optional)
  • Sponsor: NIH, National Institute on Aging (NIA)
  • Deadline: February 5 or June 5
  • Upper amount: Up to $1.5 million per year

Mood and Psychosis Symptoms During the Menopause Transition (R01 Clinical Trial Optional)

  • Sponsor: NIH, National Institute of Mental Health (NIMH)
  • Deadline: June 5
  • Upper amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

Feasibility Trials of the NIH Music-based Interventions Toolkit for Brain Disorders of Aging (R34 Clinical Trial Required)

  • Sponsor: NIH, National Center for Complementary and Integrative Health (NCCIH), National Institute on Aging (NIA)
  • Deadline: June 20
  • Upper amount: Maximum of $450,000 for the entire project period

Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)

  • Sponsor: NIH, National Cancer Institute (NCI)
  • Deadline: June 11
  • Upper amount: Up to $600,000 per year, for up to five years

More Resources

Thank You For Reading

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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office