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Exploring host-pathogen interactions and immunological mechanisms.

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News and Publications

Recent Publications

AA147 Alleviates Symptoms in a Mouse Model of Multiple Sclerosis by Reducing Oligodendrocyte Loss.

Aksu M, Kaschke K, Podojil JR, Chiang M, Steckler I, Bruce K, Cogswell AC, Schulz G, Kelly JW, Wiseman RL, Miller SD, Popko B, Chen Y.

Glia. 2025 Feb 10. doi: 10.1002/glia.70001. Online ahead of print.

Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4.

Vats A, Braga L, Kavcic N, Massimi P, Schneider E, Giacca M, Laimins LA, Banks L.

mBio. 2025 Feb 5;16(2):e0278324. doi: 10.1128/mbio.02783-24. Epub 2024 Dec 17.

The gE/gI complex is necessary for kinesin-1 recruitment during alphaherpesvirus egress from neurons.

Diwaker D, Kim D, Cordova-Martinez D, Pujari N, Jordan BA, Smith GA, Wilson DW.

J Virol. 2025 Jan 31;99(1):e0165024. doi: 10.1128/jvi.01650-24. Epub 2024 Dec 9.

Tethered release of the pseudorabies virus deubiquitinase from the capsid promotes enzymatic activity.

Antinone SE, Miller JS, Huffmaster NJ, Pickard GE, Smith GA.

J Virol. 2025 Jan 31;99(1):e0151724. doi: 10.1128/jvi.01517-24. Epub 2024 Dec 5.

Structural analysis of extracellular ATP-independent chaperones of streptococcal species and protein substrate interactions.

Agbavor C, Torres M, Inniss NL, Latimer S, Minasov G, Shuvalova L, Wawrzak Z, Borek D, Otwinowski Z, Stogios PJ, Savchenko A, Anderson WF, Satchell KJF, Cahoon LA.

mSphere. 2025 Jan 29:e0107824. doi: 10.1128/msphere.01078-24. Online ahead of print.

What We Do

Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.

Research

We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response. 
EXPLORE OUR AREAS OF FOCUS

Education

Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
SEE TRAINING OPPORTUNITIES

Center for Structural Biology of Infectious Diseases

The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

VISIT THE CSBID SITE

Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.

VISIT BASIC SCIENCE ADMINISTRATION SITE

Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE Starzl Academy Site