Innovative, collaborative research.

Congrats to our own Ann Kennedy, PhD, who has been named a Pew Scholar.

The Department of Neuroscience at Northwestern University Feinberg School of Medicine is devoted to outstanding research and committed to excellence in education. Our faculty participate in teaching medical and graduate students and are proud of their contribution to this important enterprise.

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What We Do

Research

Our research spans the full spectrum of investigation into neural function and dysfunction, bridging the levels of genes, molecules, dendrites, axons, cell types, circuits, systems and behavior.

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Education

In addition to directing their own independent research programs, our faculty are responsible for supervising the research training of postdoctoral fellows and graduate students.

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News

Embryo’s Signaling Mechanism May Promote Healthy Aging, Combat Neurodegenerative Diseases

Goyal and Kennedy Named 2024 Pew Scholars

Feinberg Scientists to Lead Grant Studying Autism, Schizophrenia

Nai-Hsing Yeh Named 2025 Houk Scholar

First-Year Student Awarded for Human Brain-Computer Interface Research

Novel Pathway Explains the Escalation of Fear Responses

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Recent Publications

ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain.

Quidé Y, Jahanshad N, Andoh J, Antoniou G, Apkarian AV, Ashar YK, Badran BW, Baird CL, Baxter L, Bell TR, Blanco-Hinojo L, Borckardt J, Cheung CL, Ciampi de Andrade D, Couto BA, Cox SR, Cruz-Almeida Y, Dannlowski U, De Martino E, de Tommaso M, Deus J, Domin M, Egorova-Brumley N, Elliott J, Fanton S, Fauchon C, Flor H, Franz CE, Gatt JM, Gerdhem P, Gilman JM, Gollub RL, Govind V, Graven-Nielsen T, Håkansson G, Hales T, Haswell C, Heukamp NJ, Hu L, Huang L, Hussain A, Jensen K, Kircher T, Kremen WS, Leehr EJ, Lindquist M, Loggia ML, Lotze M, Martucci KT, Meeker TJ, Meinert S, Millard SK, Morey RA, Murillo C, Nees F, Nenadic I, Park HRP, Peng X, Ploner M, Pujol J, Robayo LE, Salan T, Seminowicz DA, Serian A, Slater R, Stein F, Stevens J, Strauss S, Sun D, Vachon-Presseau E, Valdes-Hernandez PA, Vanneste S, Vernon M, Verriotis M, Wager TD, Widerstrom-Noga E, Woodbury A, Zeidan F, Bhatt RR, Ching CRK, Haddad E, Thomopoulos SI, Thompson PM, Gustin SM.

Pain. 2024 Jul 26. doi: 10.1097/j.pain.0000000000003317. Online ahead of print.

Ca²⁺-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses.

Zhai S, Otsuka S, Xu J, Clarke VRJ, Tkatch T, Wokosin D, Xie Z, Tanimura A, Agarwal HK, Ellis-Davies GCR, Contractor A, Surmeier DJ.

Cell Rep. 2024 Jul 25;43(8):114540. doi: 10.1016/j.celrep.2024.114540. Online ahead of print.

Author Correction: Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson's disease.

Summa KC, Jiang P, González-Rodríguez P, Huang X, Lin X, Vitaterna MH, Dan Y, Surmeier DJ, Turek FW.

NPJ Parkinsons Dis. 2024 Jul 15;10(1):131. doi: 10.1038/s41531-024-00746-7.

The NKCC1 inhibitor bumetanide restores cortical feedforward inhibition and lessens sensory hypersensitivity in early postnatal fragile X mice.

Kourdougli N, Nomura T, Wu M, Heuvelmans A, Dobler Z, Contractor A, Portera-Cailliau C.

Biol Psychiatry. 2024 Jun 29:S0006-3223(24)01427-6. doi: 10.1016/j.biopsych.2024.06.023. Online ahead of print.

Research Priorities on the Role of α-Synuclein in Parkinson's Disease Pathogenesis.

Burré J, Edwards RH, Halliday G, Lang AE, Lashuel HA, Melki R, Murayama S, Outeiro TF, Papa SM, Stefanis L, Woerman AL, Surmeier DJ, Kalia LV, Takahashi R; MDS Scientific Issues Committee.

Mov Disord. 2024 Jun 30. doi: 10.1002/mds.29897. Online ahead of print.

Metabolic Insight into Glioma Heterogeneity: Mapping Whole Exome Sequencing to In Vivo Imaging with Stereotactic Localization and Deep Learning.

Servati M, Vaccaro CN, Diller EE, Pellegrino Da Silva R, Mafra F, Cao S, Stanley KB, Cohen-Gadol AA, Parker JG.

Metabolites. 2024 Jun 16;14(6):337. doi: 10.3390/metabo14060337.

Less is more: selection from a small set of options improves BCI velocity control.

Alcolea P, Ma X, Bodkin K, Miller LE, Danziger ZC.

bioRxiv [Preprint]. 2024 Jun 3:2024.06.03.596241. doi: 10.1101/2024.06.03.596241.

Prognostic value of preoperative mechanical hyperalgesia and neuropathic pain qualities for postoperative pain after total knee replacement.

Vigotsky AD, Cong O, Pinto CB, Barroso J, Perez J, Petersen KK, Arendt-Nielsen L, Hardt KD, Manning D, Apkarian AV, Branco P.

Eur J Pain. 2024 Jun 8. doi: 10.1002/ejp.2295. Online ahead of print.

Phenotypical, genotypical and pathological characterization of the moonwalker mouse, a model of ataxia.

Sekerková G, Kilic S, Cheng YH, Fredrick N, Osmani A, Kim H, Opal P, Martina M.

Neurobiol Dis. 2024 Jun 1;195:106492. doi: 10.1016/j.nbd.2024.106492. Epub 2024 Apr 2.

Correction: Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B^-/- mice.

Wang YZ, Perez-Rosello T, Smukowski SN, Surmeier DJ, Savas JN.

Mol Psychiatry. 2024 Mar 28. doi: 10.1038/s41380-024-02543-3. Online ahead of print.

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Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.

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Starzl Academy

Physician-Scientist Training & Resources

We offer a wide range of resources, mentorship opportunities and formal training programs to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

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