Publications

Newly identified prions in budding yeast, and their possible functions.
Crow ET, Li L.
Semin Cell Dev Biol. 2011 Mar 21. [Epub ahead of print].
PMID: 21397710

[SWI+], the prion formed by the chromatin remodeling factor Swi1, is highly sensitive to alterations in Hsp70 chaperone system activity.
Hines JK, Li X, Du Z, Higurashi T, Li L, and Craig EA.
PLoS Genet. 2011 Feb;7(2):e1001309. Epub 2011 Feb 17.
PMID: 21379326

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy.
Fushimi K, Long C, Jayaram N, Chen X, Li L, and Wu J.
Protein Cell. 2011 Feb;2(2):141-9. Epub 2011 Feb 14.
PMID: 21327870

Prion protein in Caenorhabditis elegans: Distinct models of anti-BAX and neuropathology.
Park KW, Li L.
Prion. 2011 Jan 10;5(1):28-38. Epub 2011 Jan 1.
PMID: 21084837

Evolution of enzymatic activities of testis-specific short-chain dehydrogenase/reductase in Drosophila.
Zhang J, Yang H, Long M, Li L, Dean AM.
J Mol Evol. 2010 Oct;71(4):241-9. Epub 2010 Aug 31.
PMID: 20809353

Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function.
Du Z, Crow ET, Kang HS, Li L.
Mol Cell Biol. 2010 Oct;30(19):4644-55. Epub 2010 Aug 2.
PMID: 20679490

New insights into prion biology from the novel [SWI+] system.
Crow E, Du Z, Li L.
Prion. 2008 Oct;2(4):141-4. Review.
PMID: 19256027

Cytoplasmic expression of mouse prion protein causes severe toxicity in Caenorhabditis elegans.
Park KW, Li L.
Biochem Biophys Res Commun. 2008 Aug 8;372(4):697-702. Epub 2008 Jun 2.
PMID: 18519028

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae.
Du Z, Park KW, Yu H, Fan Q, Li L.
Nat Genet. 2008 Apr;40(4):460-5. Epub 2008 Mar 23.
PMID: 18362884

The role of Sse1 in the de novo formation and variant determination of the [PSI+] prion.
Fan Q, Park KW, Du Z, Morano KA, Li L.
Genetics. 2007 Nov;177(3):1583-93.
PMID: 18039878

De novo appearance and "strain" formation of yeast prion [PSI+] are regulated by the heat-shock transcription factor.
Park KW, Hahn JS, Fan Q, Thiele DJ, Li L.
Genetics. 2006 May;173(1):35-47. Epub 2006 Feb 1.
PMID: 16452152

Translational effects of differential codon usage among intragenic domains of new genes in Drosophila.
Zhang J, Long M, Li L.
Biochim Biophys Acta. 2005 May 1;1728(3):135-42. Epub 2005 Mar 2.
PMID: 15833448

Investigating protein conformation-based inheritance and disease in yeast.
Lindquist S, Krobitsch S, Li L, Sondheimer N.
Philos Trans R Soc Lond B Biol Sci. 2001 Feb 28;356(1406):169-76. Review.
PMID: 11260797

Creating a protein-based element of inheritance.
Li L, Lindquist S.
Science. 2000 Jan 28;287(5453):661-4.
PMID: 10650001