Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityNews & Breakthroughs
Read the latest news from Northwestern Medicine Lou and Jean Malnati Brain Tumor Institute. The links below take you to articles where you can learn more about our latest events and accomplishments.
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11.20.2024Patients with a subtype of glioblastoma who received a combination treatment of a PARP inhibitor and standard chemotherapy did not demonstrate improved survival compared to chemotherapy and placebo, according to a recent clinical trial published in JAMA Oncology.
10.16.2024The average length of survival for glioblastoma has failed to improve since it was first identified in scientific literature nearly 100 years ago. Despite this, scientists at Feinberg remain steadfast in their commitment to improving the understanding and treatment of glioblastoma through rigorous research initiatives and clinical trials.
09.23.2024Harnessing the body’s own B-cells to fight tumors may be a promising treatment for glioblastoma, according to a Northwestern Medicine study recently published in the Journal of Clinical Investigation.
09.19.2024A new Northwestern Medicine study may better inform doctors’ decisions about which brain areas to preserve during surgery, thereby improving patients’ language function after brain surgery.
09.10.2024Investigators have demonstrated how molecular profiling of tumors can be used to help predict treatment response and survival in patients with meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Medicine.
08.19.2024Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
06.17.2024Investigators have discovered that using a novel drug agonist to target the STING pathway in preclinical models of glioblastoma reprogrammed previously suppressed immune responses, according to recent findings published in the Journal of Clinical Investigation.
06.06.2024Northwestern Medicine scientists have used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy, a major advance for the treatment of this deadly cancer.
- 05.17.2024
Investigators have discovered new mechanisms underlying intratumor heterogeneity and treatment resistance in meningiomas, the most common type of primary central nervous system tumor, according to a recent study published in Nature Genetics.
05.16.2024A recent study from the laboratory of Shi-Yuan Cheng, PhD, has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in The Journal of Clinical Investigation.
03.26.2024Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature Communications.
- 03.20.2024
Northwestern Medicine investigators led by Amy Heimberger, MD, PhD, have discovered a new mechanism in which cancer-associated fibroblasts are associated with tumor grade and mediate immune suppression in glioma tumors.
03.01.2024An experimental drug may provide a new treatment option for some patients with rare incurable brain tumors, according to an analysis published in the Journal of Clinical Oncology.
01.22.2024The drug tovorafenib may halt the growth of or shrink some childhood brain tumors, according to a clinical trial published in Nature Medicine.
01.18.2024A multidisciplinary team of investigators has developed a first-of-its-kind interactive 3D spatial approach that reveals new therapeutic targets and provides a comprehensive three-dimensional view of glioblastoma tumors, detailed in a recent study published in Cell.
01.02.2024Northwestern Medicine investigators have discovered that specialized immune cells within the glioblastoma tumor microenvironment use a unique “feeding” mechanism that promotes tumor growth and treatment resistance, according to findings published in the journal Cell Metabolism.
12.26.2023Feinberg experienced a year of outstanding growth, scientific achievement, and collaboration in 2023, from honors and awards to unprecedented research discoveries.