Publications
Browse the list below to see the latest scientific publications stemming from our center faculty’s work. To view publications of specific CHIP faculty, please visit About Us and select a profile link.
- Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C et al. Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration. Bioact Mater 2024 Nov;41:427-439. doi:10.1016/j.bioactmat.2024.07.029
- Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ et al. Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs. NPJ Digit Med 2024 Sep 28;7(1):260. pii:260
- Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Wei WQ, Jarvik G, Mooney S, Crosslin D Language-model-based patient embedding using electronic health records facilitates phenotyping, disease forecasting, and progression analysis. Res Sq 2024 Sep 23;. pii:rs.3.rs-4708839
- Guare LA, Humphrey LA, Rush M, Pollie M, Jaworski J, Akerele AT, Luo Y, Weng C, We WQ, Kottyan L et al. Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records. Res Sq 2024 Sep 09;. pii:rs.3.rs-5004325
- Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S et al. A Common Longitudinal Intensive Care Unit data Format (CLIF) to enable multi-institutional federated critical illness research. medRxiv 2024 Sep 04;. pii:2024.09.04.24313058
- Luo Y, Meng X, Zhou G, Zhou J, Luo YJ, Ai H, Zelano C, Chen F, Xu P Oscillatory mechanisms of intrinsic human brain networks. Neuroimage 2024 Sep;298:120773. doi:10.1016/j.neuroimage.2024.120773
- Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B et al. Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system. Clin Res Cardiol 2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
- Amagai S, Vonesh E, Adams J, Luo Y Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era. NPJ Digit Med 2024 Aug 21;7(1):217. pii:217
- Li Y, Luo Y STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks. Genome Biol 2024 Aug 05;25(1):206. pii:206
- Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S et al. Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system. Learn Health Syst 2024 Jul;8(3):e10417. pii:e10417
- Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020. JACC Heart Fail 2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
- Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ et al. Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock. Pediatr Crit Care Med 2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
- Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J et al. Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach. Front Immunol 2024;15:1331959. pii:1331959
- Li Y, Wu X, Fang D, Luo Y Informing immunotherapy with multi-omics driven machine learning. NPJ Digit Med 2024 Mar 14;7(1):67. pii:67
- Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ et al. Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study. Res Sq 2024 Mar 11;. pii:rs.3.rs-4014472
- Deng Y, Pacheco JA, Ghosh A, Chung A, Mao C, Smith JC, Zhao J, Wei WQ, Barnado A, Dorn C et al. Natural language processing to identify lupus nephritis phenotype in electronic health records. BMC Med Inform Decis Mak 2024 Mar 03;22(Suppl 2):348. pii:348
- Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ et al. Identification of Clinical Drivers of Left Atrial Enlargement Through Genomics of Left Atrial Size. Circ Heart Fail 2024 Jan;17(1):e010557. doi:10.1161/CIRCHEARTFAILURE.123.010557
- Eickelberg G, Sanchez-Pinto LN, Kline AS, Luo Y Transportability of bacterial infection prediction models for critically ill patients. J Am Med Inform Assoc 2023 Dec 22;31(1):98-108. doi:10.1093/jamia/ocad174
- Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL et al. Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease. Nat Commun 2023 Nov 30;14(1):7836. pii:7836
- Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ et al. Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. Sci Rep 2023 Nov 15;13(1):19972. pii:19972
- Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R et al. Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study. EClinicalMedicine 2023 Nov;65:102252. pii:102252
- Ross SM, Wang A, Anthony L, Persell SD, Yu J, Kho AN Is more better? The impact of implementing more interventions for hypertension control in a practice facilitation study for small- and medium-sized practices. J Hum Hypertens 2023 Nov;37(11):1007-1014. doi:10.1038/s41371-023-00813-1
- Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ et al. Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. Sci Rep 2023 Oct 28;13(1):18532. pii:18532
- Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A An exploratory survey about using ChatGPT in education, healthcare, and research. PLoS One 2023;18(10):e0292216. pii:e0292216
- Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network. Lupus Sci Med 2023 Oct;10(2). pii:e000963
- Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C et al. Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study. Contemp Clin Trials Commun 2023 Oct;35:101199. pii:101199
- Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW et al. Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock. Pediatr Crit Care Med 2023 Oct 01;24(10):795-806. doi:10.1097/PCC.0000000000003292
- McHugh M, Heinrich J, Philbin S, Bishop D, Smith JD, Knapke JM, Day A, Walunas TL Declining Participation in Primary Care Quality Improvement Research: A Qualitative Study. Ann Fam Med 2023;21(5):388-394. doi:10.1370/afm.3007
- Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ et al. External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock. Res Sq 2023 Aug 02;. pii:rs.3.rs-3216613
- Mao C, Xu J, Rasmussen L, Li Y, Adekkanattu P, Pacheco J, Bonakdarpour B, Vassar R, Shen L, Jiang G et al. AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease. J Biomed Inform 2023 Aug;144:104442. doi:10.1016/j.jbi.2023.104442
- Wang H, Ding YJ, Luo Y Future of ChatGPT in Pharmacovigilance. Drug Saf 2023 Aug;46(8):711-713. doi:10.1007/s40264-023-01315-2
- Naidech AM, Wang H, Hutch M, Murphy J, Paparello J, Bath P, Srivastava A, Luo Y Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial. BMJ Neurol Open 2023;5(2):e000458. pii:e000458
- Cousins HC, Kline AS, Wang C, Qu Y, Zengel J, Carette J, Wang M, Altman RB, Luo Y, Cong L Integrative analysis of functional genomic screening and clinical data identifies a protective role for spironolactone in severe COVID-19. Cell Rep Methods 2023 Jul 24;3(7):100503. pii:100503
- Canning C, Guo J, Narang A, Thomas JD, Ahmad FS The Emerging Role of Artificial Intelligence in Valvular Heart Disease. Heart Fail Clin 2023 Jul;19(3):391-405. doi:10.1016/j.hfc.2023.03.001
- Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK et al. Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients. Clin Immunol 2023 Jul;252:109634. doi:10.1016/j.clim.2023.109634
- Bilaver LA, Wang H, Naidech AM, Luo Y, Das R, Sehgal S, Gupta R Natural language processing of pediatric progress notes for the identification of food allergy. J Allergy Clin Immunol Pract 2023 Jul;11(7):2242-2244.e2. doi:10.1016/j.jaip.2023.04.014
- Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD et al. Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study. Brain Behav Immun 2023 Jul;111:116-123. doi:10.1016/j.bbi.2023.03.024
- Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM et al. Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19. J Clin Invest 2023 Jun 15;133(12). pii:e170682
- Li Y, Luo Y Spatial Transcriptomic Cell-type Deconvolution Using Graph Neural Networks. bioRxiv 2023 Jun 09;. pii:2023.03.10.532112
- Schepart A, Burton A, Durkin L, Fuller A, Charap E, Bhambri R, Ahmad FS Artificial intelligence-enabled tools in cardiovascular medicine: A survey of current use, perceptions, and challenges. Cardiovasc Digit Health J 2023 Jun;4(3):101-110. doi:10.1016/j.cvdhj.2023.04.003
- Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A et al. Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm. PLoS One 2023;18(5):e0283553. pii:e0283553
- Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S et al. Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish. Sci Adv 2023 Apr 28;9(17):eade0631. pii:eade0631
- Gao CA, Howard FM, Markov NS, Dyer EC, Ramesh S, Luo Y, Pearson AT Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers. NPJ Digit Med 2023 Apr 26;6(1):75. pii:75
- Wang H, Li Y, Hutch MR, Kline AS, Otero S, Mithal LB, Miller ES, Naidech A, Luo Y Patterns of diverse and changing sentiments towards COVID-19 vaccines: a sentiment analysis study integrating 11 million tweets and surveillance data across over 180 countries. J Am Med Inform Assoc 2023 Apr 19;30(5):923-931. doi:10.1093/jamia/ocad029
- Hosseini M, Gao CA, Liebovitz D, Carvalho A, Ahmad FS, Luo Y, MacDonald N, Holmes K, Kho A An exploratory survey about using ChatGPT in education, healthcare, and research. medRxiv 2023 Apr 03;. pii:2023.03.31.23287979
- Liu Y, Luo Y, Naidech AM Big Data in Stroke: How to Use Big Data to Make the Next Management Decision. Neurotherapeutics 2023 Apr;20(3):744-757. doi:10.1007/s13311-023-01358-4
- Xiao B, Velez Edwards DR, Lucas A, Drivas T, Gray K, Keating B, Weng C, Jarvik GP, Hakonarson H, Kottyan L et al. Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions. J Am Heart Assoc 2023 Mar 07;12(5):e026561. pii:e026561
- Furmanchuk A, Rydland KJ, Hsia RY, Mackersie R, Shi M, Hauser MW, Kho A, Bilimoria KY, Stey AM Geographic Disparities in Re-triage Destinations Among Seriously Injured Californians. Ann Surg Open 2023 Mar;4(1). pii:e270
- Bunney G, Tran S, Han S, Gu C, Wang H, Luo Y, Dresden S Using Machine Learning to Predict Hospital Disposition With Geriatric Emergency Department Innovation Intervention. Ann Emerg Med 2023 Mar;81(3):353-363. doi:10.1016/j.annemergmed.2022.07.026
- Kim M, Kwasny MJ, Bailey SC, Benavente JY, Zheng P, Bonham M, Luu HQ, Cecil P, Agyare P, O'Conor R et al. MidCog study: a prospective, observational cohort study investigating health literacy, self-management skills and cognitive function in middle-aged adults. BMJ Open 2023 Feb 23;13(2):e071899. pii:e071899