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Publications

Browse the list below to see the latest scientific publications stemming from our center faculty’s work. To view publications of specific CHIP faculty, please visit About Us and select a profile link.

  1. Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C  et al.  Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration.  Bioact Mater  2024 Nov;41:427-439. doi:10.1016/j.bioactmat.2024.07.029
  2. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs.  NPJ Digit Med  2024 Sep 28;7(1):260. pii:260
  3. Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Wei WQ, Jarvik G, Mooney S, Crosslin D  Language-model-based patient embedding using electronic health records facilitates phenotyping, disease forecasting, and progression analysis.  Res Sq  2024 Sep 23;. pii:rs.3.rs-4708839
  4. Guare LA, Humphrey LA, Rush M, Pollie M, Jaworski J, Akerele AT, Luo Y, Weng C, We WQ, Kottyan L  et al.  Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records.  Res Sq  2024 Sep 09;. pii:rs.3.rs-5004325
  5. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A Common Longitudinal Intensive Care Unit data Format (CLIF) to enable multi-institutional federated critical illness research.  medRxiv  2024 Sep 04;. pii:2024.09.04.24313058
  6. Luo Y, Meng X, Zhou G, Zhou J, Luo YJ, Ai H, Zelano C, Chen F, Xu P  Oscillatory mechanisms of intrinsic human brain networks.  Neuroimage  2024 Sep;298:120773. doi:10.1016/j.neuroimage.2024.120773
  7. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  8. Amagai S, Vonesh E, Adams J, Luo Y  Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era.  NPJ Digit Med  2024 Aug 21;7(1):217. pii:217
  9. Li Y, Luo Y  STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks.  Genome Biol  2024 Aug 05;25(1):206. pii:206
  10. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  11. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
  12. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  13. Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J  et al.  Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.  Front Immunol  2024;15:1331959. pii:1331959
  14. Li Y, Wu X, Fang D, Luo Y  Informing immunotherapy with multi-omics driven machine learning.  NPJ Digit Med  2024 Mar 14;7(1):67. pii:67
  15. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study.  Res Sq  2024 Mar 11;. pii:rs.3.rs-4014472
  16. Deng Y, Pacheco JA, Ghosh A, Chung A, Mao C, Smith JC, Zhao J, Wei WQ, Barnado A, Dorn C  et al.  Natural language processing to identify lupus nephritis phenotype in electronic health records.  BMC Med Inform Decis Mak  2024 Mar 03;22(Suppl 2):348. pii:348
  17. Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ  et al.  Identification of Clinical Drivers of Left Atrial Enlargement Through Genomics of Left Atrial Size.  Circ Heart Fail  2024 Jan;17(1):e010557. doi:10.1161/CIRCHEARTFAILURE.123.010557
  18. Eickelberg G, Sanchez-Pinto LN, Kline AS, Luo Y  Transportability of bacterial infection prediction models for critically ill patients.  J Am Med Inform Assoc  2023 Dec 22;31(1):98-108. doi:10.1093/jamia/ocad174
  19. Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL  et al.  Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.  Nat Commun  2023 Nov 30;14(1):7836. pii:7836
  20. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Nov 15;13(1):19972. pii:19972
  21. Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R  et al.  Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.  EClinicalMedicine  2023 Nov;65:102252. pii:102252
  22. Ross SM, Wang A, Anthony L, Persell SD, Yu J, Kho AN  Is more better? The impact of implementing more interventions for hypertension control in a practice facilitation study for small- and medium-sized practices.  J Hum Hypertens  2023 Nov;37(11):1007-1014. doi:10.1038/s41371-023-00813-1
  23. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Oct 28;13(1):18532. pii:18532
  24. Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  PLoS One  2023;18(10):e0292216. pii:e0292216
  25. Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL  Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network.  Lupus Sci Med  2023 Oct;10(2). pii:e000963
  26. Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C  et al.  Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study.  Contemp Clin Trials Commun  2023 Oct;35:101199. pii:101199
  27. Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW  et al.  Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2023 Oct 01;24(10):795-806. doi:10.1097/PCC.0000000000003292
  28. McHugh M, Heinrich J, Philbin S, Bishop D, Smith JD, Knapke JM, Day A, Walunas TL  Declining Participation in Primary Care Quality Improvement Research: A Qualitative Study.  Ann Fam Med  2023;21(5):388-394. doi:10.1370/afm.3007
  29. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock.  Res Sq  2023 Aug 02;. pii:rs.3.rs-3216613
  30. Mao C, Xu J, Rasmussen L, Li Y, Adekkanattu P, Pacheco J, Bonakdarpour B, Vassar R, Shen L, Jiang G  et al.  AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease.  J Biomed Inform  2023 Aug;144:104442. doi:10.1016/j.jbi.2023.104442
  31. Wang H, Ding YJ, Luo Y  Future of ChatGPT in Pharmacovigilance.  Drug Saf  2023 Aug;46(8):711-713. doi:10.1007/s40264-023-01315-2
  32. Naidech AM, Wang H, Hutch M, Murphy J, Paparello J, Bath P, Srivastava A, Luo Y  Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial.  BMJ Neurol Open  2023;5(2):e000458. pii:e000458
  33. Cousins HC, Kline AS, Wang C, Qu Y, Zengel J, Carette J, Wang M, Altman RB, Luo Y, Cong L  Integrative analysis of functional genomic screening and clinical data identifies a protective role for spironolactone in severe COVID-19.  Cell Rep Methods  2023 Jul 24;3(7):100503. pii:100503
  34. Canning C, Guo J, Narang A, Thomas JD, Ahmad FS  The Emerging Role of Artificial Intelligence in Valvular Heart Disease.  Heart Fail Clin  2023 Jul;19(3):391-405. doi:10.1016/j.hfc.2023.03.001
  35. Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK  et al.  Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients.  Clin Immunol  2023 Jul;252:109634. doi:10.1016/j.clim.2023.109634
  36. Bilaver LA, Wang H, Naidech AM, Luo Y, Das R, Sehgal S, Gupta R  Natural language processing of pediatric progress notes for the identification of food allergy.  J Allergy Clin Immunol Pract  2023 Jul;11(7):2242-2244.e2. doi:10.1016/j.jaip.2023.04.014
  37. Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD  et al.  Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study.  Brain Behav Immun  2023 Jul;111:116-123. doi:10.1016/j.bbi.2023.03.024
  38. Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM  et al.  Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19.  J Clin Invest  2023 Jun 15;133(12). pii:e170682
  39. Li Y, Luo Y  Spatial Transcriptomic Cell-type Deconvolution Using Graph Neural Networks.  bioRxiv  2023 Jun 09;. pii:2023.03.10.532112
  40. Schepart A, Burton A, Durkin L, Fuller A, Charap E, Bhambri R, Ahmad FS  Artificial intelligence-enabled tools in cardiovascular medicine: A survey of current use, perceptions, and challenges.  Cardiovasc Digit Health J  2023 Jun;4(3):101-110. doi:10.1016/j.cvdhj.2023.04.003
  41. Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A  et al.  Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm.  PLoS One  2023;18(5):e0283553. pii:e0283553
  42. Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S  et al.  Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish.  Sci Adv  2023 Apr 28;9(17):eade0631. pii:eade0631
  43. Gao CA, Howard FM, Markov NS, Dyer EC, Ramesh S, Luo Y, Pearson AT  Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers.  NPJ Digit Med  2023 Apr 26;6(1):75. pii:75
  44. Wang H, Li Y, Hutch MR, Kline AS, Otero S, Mithal LB, Miller ES, Naidech A, Luo Y  Patterns of diverse and changing sentiments towards COVID-19 vaccines: a sentiment analysis study integrating 11 million tweets and surveillance data across over 180 countries.  J Am Med Inform Assoc  2023 Apr 19;30(5):923-931. doi:10.1093/jamia/ocad029
  45. Hosseini M, Gao CA, Liebovitz D, Carvalho A, Ahmad FS, Luo Y, MacDonald N, Holmes K, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  medRxiv  2023 Apr 03;. pii:2023.03.31.23287979
  46. Liu Y, Luo Y, Naidech AM  Big Data in Stroke: How to Use Big Data to Make the Next Management Decision.  Neurotherapeutics  2023 Apr;20(3):744-757. doi:10.1007/s13311-023-01358-4
  47. Xiao B, Velez Edwards DR, Lucas A, Drivas T, Gray K, Keating B, Weng C, Jarvik GP, Hakonarson H, Kottyan L  et al.  Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.  J Am Heart Assoc  2023 Mar 07;12(5):e026561. pii:e026561
  48. Furmanchuk A, Rydland KJ, Hsia RY, Mackersie R, Shi M, Hauser MW, Kho A, Bilimoria KY, Stey AM  Geographic Disparities in Re-triage Destinations Among Seriously Injured Californians.  Ann Surg Open  2023 Mar;4(1). pii:e270
  49. Bunney G, Tran S, Han S, Gu C, Wang H, Luo Y, Dresden S  Using Machine Learning to Predict Hospital Disposition With Geriatric Emergency Department Innovation Intervention.  Ann Emerg Med  2023 Mar;81(3):353-363. doi:10.1016/j.annemergmed.2022.07.026
  50. Kim M, Kwasny MJ, Bailey SC, Benavente JY, Zheng P, Bonham M, Luu HQ, Cecil P, Agyare P, O'Conor R  et al.  MidCog study: a prospective, observational cohort study investigating health literacy, self-management skills and cognitive function in middle-aged adults.  BMJ Open  2023 Feb 23;13(2):e071899. pii:e071899

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