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Northwestern University Feinberg School of Medicine
Center for Health Information Partnerships

Publications

Browse the list below to see the latest scientific publications stemming from our center faculty’s work. To view publications of specific CHIP faculty, please visit About Us and select a profile link.

  1. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Apr 09;. doi:10.1245/s10434-025-17204-0
  2. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  Correction: A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar 31;. doi:10.1007/s00134-025-07869-2
  3. Wang A, French D, Black B, Kho AN  Cohort study examining social determinants of health and their association with mortality among hospitalised adults in New York and California.  BMJ Public Health  2025 Jan;3(1):e001266. pii:e001266
  4. Eduardo MB, Cottone G, McCloskey CW, Liu S, Palma FR, Zappia MP, Islam ABMMK, Gao P, Setya J, Dennis S  et al.  A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells.  Sci Adv  2025 Mar 21;11(12):eads9182. pii:eads9182
  5. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung W, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic Method for Classifying Multiple Congenital Anomaly Cases in Electronic Health Records.  Genet Med  2025 Mar 18;:101415. doi:10.1016/j.gim.2025.101415
  6. Amagai S, Chaudhari V, Chhikara K, Ingraham NE, Hochberg CH, Barker AK, Mao C, Ortiz AC, Weissman GE, Schmid BE  et al.  The Epidemiology of Intensive Care Unit Readmissions Across Ten Health Systems.  medRxiv  2025 Mar 13;. pii:2025.03.10.25323672
  7. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar 13;. doi:10.1007/s00134-025-07848-7
  8. Eisinger-Mathason TSK, Leshin J, Lahoti V, Fridsma DB, Mucaj V, Kho AN  Data linkage multiplies research insights across diverse healthcare sectors.  Commun Med (Lond)  2025 Mar 04;5(1):58. pii:58
  9. Luo Y, Li Y, Ogunyemi O, Koski E, Himes BE  Leveraging large language models for academic conference organization.  NPJ Digit Med  2025 Feb 14;8(1):101. pii:101
  10. Theros J, Soetikno A, Liebovitz D  Foundations of AI for future physicians: A practical, accessible curriculum.  Med Teach  2025 Feb 12;:1-3. doi:10.1080/0142159X.2025.2463492
  11. Zhou X, Zhou J, Wang C, Xie Q, Ding K, Mao C, Liu Y, Cao Z, Chu H, Chen X  et al.  PH-LLM: Public Health Large Language Models for Infoveillance.  medRxiv  2025 Feb 10;. pii:2025.02.08.25321587
  12. Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N  et al.  Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.  Science  2025 Feb 07;387(6734):eadp4753. doi:10.1126/science.adp4753
  13. Tran SD, Forrest NJ, Guggilla V, Perottino GM, Johnson JL, Sosman J, Roy I, Walunas TL  Weight and Blood-Based Markers of Cachexia Predict Disability, Hospitalization and Worse Survival in Cancer Immunotherapy Patients.  J Cachexia Sarcopenia Muscle  2025 Feb;16(1):e13685. pii:e13685
  14. Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN  Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care.  Contemp Clin Trials Commun  2025 Feb;43:101413. pii:101413
  15. Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB  et al.  Micropillar-induced changes in cell nucleus morphology enhance bone regeneration by modulating the secretome.  Res Sq  2025 Jan 07;. pii:rs.3.rs-5530535
  16. Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ  Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma.  PLoS One  2025;20(1):e0312415. pii:e0312415
  17. Forrest N, Tran S, Nandoliya KR, Houskamp EJ, Gruchala T, Guggilla V, Sun Z, Lukas R, Wainwright D, Furmanchuk A  et al.  A Dynamic Time Warping Extension to Consensus Weight-Based Cachexia Criteria Improves Prediction of Cancer Patient Outcomes.  JCSM Commun  2025;8(1):e107. pii:e107
  18. Idnay B, Xu Z, Adams WG, Adibuzzaman M, Anderson NR, Bahroos N, Bell DS, Bumgardner C, Campion T, Castro M  et al.  Environment scan of generative AI infrastructure for clinical and translational science.  Npj Health Syst  2025;2(1):4. pii:4
  19. Naved BA, Luo Y  Contrasting rule and machine learning based digital self triage systems in the USA.  NPJ Digit Med  2024 Dec 27;7(1):381. pii:381
  20. Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP  et al.  Interleukin 8-CXCR2-mediated neutrophil extracellular trap formation in biliary atresia associated with neutrophil extracellular trap-induced stellate cell activation.  Hepatology  2024 Dec 18;. doi:10.1097/HEP.0000000000001195
  21. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  Res Sq  2024 Dec 16;. pii:rs.3.rs-5487737
  22. Shin J, Luo Y  Relationship between exposure to multiple heavy metals and depressive symptoms in the US: The impact of alcohol consumption.  Heliyon  2024 Dec 15;10(23):e40221. pii:e40221
  23. Wang MC, Awoyemi T, Allen NB, Shah R, Nayor M, Luo Y, Lima JAC, Lloyd-Jones DM, Khan SS  Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study.  Am J Prev Cardiol  2024 Dec;20:100889. pii:100889
  24. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  medRxiv  2024 Nov 20;. pii:2024.11.19.24317559
  25. Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C  et al.  Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration.  Bioact Mater  2024 Nov;41:427-439. doi:10.1016/j.bioactmat.2024.07.029
  26. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs.  NPJ Digit Med  2024 Sep 28;7(1):260. pii:260
  27. Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Wei WQ, Jarvik G, Mooney S, Crosslin D  Language-model-based patient embedding using electronic health records facilitates phenotyping, disease forecasting, and progression analysis.  Res Sq  2024 Sep 23;. pii:rs.3.rs-4708839
  28. Guare LA, Humphrey LA, Rush M, Pollie M, Jaworski J, Akerele AT, Luo Y, Weng C, We WQ, Kottyan L  et al.  Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records.  Res Sq  2024 Sep 09;. pii:rs.3.rs-5004325
  29. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A Common Longitudinal Intensive Care Unit data Format (CLIF) to enable multi-institutional federated critical illness research.  medRxiv  2024 Sep 04;. pii:2024.09.04.24313058
  30. Luo Y, Meng X, Zhou G, Zhou J, Luo YJ, Ai H, Zelano C, Chen F, Xu P  Oscillatory mechanisms of intrinsic human brain networks.  Neuroimage  2024 Sep;298:120773. doi:10.1016/j.neuroimage.2024.120773
  31. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  32. Amagai S, Vonesh E, Adams J, Luo Y  Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era.  NPJ Digit Med  2024 Aug 21;7(1):217. pii:217
  33. Li Y, Luo Y  STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks.  Genome Biol  2024 Aug 05;25(1):206. pii:206
  34. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  35. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
  36. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  37. Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J  et al.  Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.  Front Immunol  2024;15:1331959. pii:1331959
  38. Li Y, Wu X, Fang D, Luo Y  Informing immunotherapy with multi-omics driven machine learning.  NPJ Digit Med  2024 Mar 14;7(1):67. pii:67
  39. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study.  Res Sq  2024 Mar 11;. pii:rs.3.rs-4014472
  40. Deng Y, Pacheco JA, Ghosh A, Chung A, Mao C, Smith JC, Zhao J, Wei WQ, Barnado A, Dorn C  et al.  Natural language processing to identify lupus nephritis phenotype in electronic health records.  BMC Med Inform Decis Mak  2024 Mar 03;22(Suppl 2):348. pii:348
  41. Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ  et al.  Identification of Clinical Drivers of Left Atrial Enlargement Through Genomics of Left Atrial Size.  Circ Heart Fail  2024 Jan;17(1):e010557. doi:10.1161/CIRCHEARTFAILURE.123.010557
  42. Eickelberg G, Sanchez-Pinto LN, Kline AS, Luo Y  Transportability of bacterial infection prediction models for critically ill patients.  J Am Med Inform Assoc  2023 Dec 22;31(1):98-108. doi:10.1093/jamia/ocad174
  43. Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL  et al.  Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.  Nat Commun  2023 Nov 30;14(1):7836. pii:7836
  44. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Nov 15;13(1):19972. pii:19972
  45. Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R  et al.  Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.  EClinicalMedicine  2023 Nov;65:102252. pii:102252
  46. Ross SM, Wang A, Anthony L, Persell SD, Yu J, Kho AN  Is more better? The impact of implementing more interventions for hypertension control in a practice facilitation study for small- and medium-sized practices.  J Hum Hypertens  2023 Nov;37(11):1007-1014. doi:10.1038/s41371-023-00813-1
  47. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Oct 28;13(1):18532. pii:18532
  48. Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  PLoS One  2023;18(10):e0292216. pii:e0292216
  49. Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL  Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network.  Lupus Sci Med  2023 Oct;10(2). pii:e000963
  50. Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C  et al.  Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study.  Contemp Clin Trials Commun  2023 Oct;35:101199. pii:101199

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