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Northwestern University Feinberg School of Medicine
Center for Health Information Partnerships

Publications

Browse the list below to see the latest scientific publications stemming from our center faculty’s work. To view publications of specific CHIP faculty, please visit About Us and select a profile link.

  1. Tran SD, Forrest NJ, Guggilla V, Perottino GM, Johnson JL, Sosman J, Roy I, Walunas TL  Weight and Blood-Based Markers of Cachexia Predict Disability, Hospitalization and Worse Survival in Cancer Immunotherapy Patients.  J Cachexia Sarcopenia Muscle  2025 Feb;16(1):e13685. pii:e13685
  2. Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN  Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care.  Contemp Clin Trials Commun  2025 Feb;43:101413. pii:101413
  3. Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ  Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma.  PLoS One  2025;20(1):e0312415. pii:e0312415
  4. Naved BA, Luo Y  Contrasting rule and machine learning based digital self triage systems in the USA.  NPJ Digit Med  2024 Dec 27;7(1):381. pii:381
  5. Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP  et al.  Interleukin 8-CXCR2 mediated neutrophil extracellular trap (NET) formation in biliary atresia associated with NET-Induced stellate cell activation.  Hepatology  2024 Dec 18;. doi:10.1097/HEP.0000000000001195
  6. Shin J, Luo Y  Relationship between exposure to multiple heavy metals and depressive symptoms in the US: The impact of alcohol consumption.  Heliyon  2024 Dec 15;10(23):e40221. pii:e40221
  7. Wang MC, Awoyemi T, Allen NB, Shah R, Nayor M, Luo Y, Lima JAC, Lloyd-Jones DM, Khan SS  Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study.  Am J Prev Cardiol  2024 Dec;20:100889. pii:100889
  8. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  medRxiv  2024 Nov 20;. pii:2024.11.19.24317559
  9. Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C  et al.  Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration.  Bioact Mater  2024 Nov;41:427-439. doi:10.1016/j.bioactmat.2024.07.029
  10. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs.  NPJ Digit Med  2024 Sep 28;7(1):260. pii:260
  11. Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Wei WQ, Jarvik G, Mooney S, Crosslin D  Language-model-based patient embedding using electronic health records facilitates phenotyping, disease forecasting, and progression analysis.  Res Sq  2024 Sep 23;. pii:rs.3.rs-4708839
  12. Guare LA, Humphrey LA, Rush M, Pollie M, Jaworski J, Akerele AT, Luo Y, Weng C, We WQ, Kottyan L  et al.  Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records.  Res Sq  2024 Sep 09;. pii:rs.3.rs-5004325
  13. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A Common Longitudinal Intensive Care Unit data Format (CLIF) to enable multi-institutional federated critical illness research.  medRxiv  2024 Sep 04;. pii:2024.09.04.24313058
  14. Luo Y, Meng X, Zhou G, Zhou J, Luo YJ, Ai H, Zelano C, Chen F, Xu P  Oscillatory mechanisms of intrinsic human brain networks.  Neuroimage  2024 Sep;298:120773. doi:10.1016/j.neuroimage.2024.120773
  15. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  16. Amagai S, Vonesh E, Adams J, Luo Y  Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era.  NPJ Digit Med  2024 Aug 21;7(1):217. pii:217
  17. Li Y, Luo Y  STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks.  Genome Biol  2024 Aug 05;25(1):206. pii:206
  18. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  19. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
  20. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  21. Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J  et al.  Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.  Front Immunol  2024;15:1331959. pii:1331959
  22. Li Y, Wu X, Fang D, Luo Y  Informing immunotherapy with multi-omics driven machine learning.  NPJ Digit Med  2024 Mar 14;7(1):67. pii:67
  23. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study.  Res Sq  2024 Mar 11;. pii:rs.3.rs-4014472
  24. Deng Y, Pacheco JA, Ghosh A, Chung A, Mao C, Smith JC, Zhao J, Wei WQ, Barnado A, Dorn C  et al.  Natural language processing to identify lupus nephritis phenotype in electronic health records.  BMC Med Inform Decis Mak  2024 Mar 03;22(Suppl 2):348. pii:348
  25. Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ  et al.  Identification of Clinical Drivers of Left Atrial Enlargement Through Genomics of Left Atrial Size.  Circ Heart Fail  2024 Jan;17(1):e010557. doi:10.1161/CIRCHEARTFAILURE.123.010557
  26. Eickelberg G, Sanchez-Pinto LN, Kline AS, Luo Y  Transportability of bacterial infection prediction models for critically ill patients.  J Am Med Inform Assoc  2023 Dec 22;31(1):98-108. doi:10.1093/jamia/ocad174
  27. Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL  et al.  Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.  Nat Commun  2023 Nov 30;14(1):7836. pii:7836
  28. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Nov 15;13(1):19972. pii:19972
  29. Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R  et al.  Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.  EClinicalMedicine  2023 Nov;65:102252. pii:102252
  30. Ross SM, Wang A, Anthony L, Persell SD, Yu J, Kho AN  Is more better? The impact of implementing more interventions for hypertension control in a practice facilitation study for small- and medium-sized practices.  J Hum Hypertens  2023 Nov;37(11):1007-1014. doi:10.1038/s41371-023-00813-1
  31. Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ  et al.  Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.  Sci Rep  2023 Oct 28;13(1):18532. pii:18532
  32. Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  PLoS One  2023;18(10):e0292216. pii:e0292216
  33. Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL  Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network.  Lupus Sci Med  2023 Oct;10(2). pii:e000963
  34. Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C  et al.  Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study.  Contemp Clin Trials Commun  2023 Oct;35:101199. pii:101199
  35. Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW  et al.  Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2023 Oct 01;24(10):795-806. doi:10.1097/PCC.0000000000003292
  36. McHugh M, Heinrich J, Philbin S, Bishop D, Smith JD, Knapke JM, Day A, Walunas TL  Declining Participation in Primary Care Quality Improvement Research: A Qualitative Study.  Ann Fam Med  2023;21(5):388-394. doi:10.1370/afm.3007
  37. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock.  Res Sq  2023 Aug 02;. pii:rs.3.rs-3216613
  38. Mao C, Xu J, Rasmussen L, Li Y, Adekkanattu P, Pacheco J, Bonakdarpour B, Vassar R, Shen L, Jiang G  et al.  AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease.  J Biomed Inform  2023 Aug;144:104442. doi:10.1016/j.jbi.2023.104442
  39. Wang H, Ding YJ, Luo Y  Future of ChatGPT in Pharmacovigilance.  Drug Saf  2023 Aug;46(8):711-713. doi:10.1007/s40264-023-01315-2
  40. Naidech AM, Wang H, Hutch M, Murphy J, Paparello J, Bath P, Srivastava A, Luo Y  Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial.  BMJ Neurol Open  2023;5(2):e000458. pii:e000458
  41. Cousins HC, Kline AS, Wang C, Qu Y, Zengel J, Carette J, Wang M, Altman RB, Luo Y, Cong L  Integrative analysis of functional genomic screening and clinical data identifies a protective role for spironolactone in severe COVID-19.  Cell Rep Methods  2023 Jul 24;3(7):100503. pii:100503
  42. Canning C, Guo J, Narang A, Thomas JD, Ahmad FS  The Emerging Role of Artificial Intelligence in Valvular Heart Disease.  Heart Fail Clin  2023 Jul;19(3):391-405. doi:10.1016/j.hfc.2023.03.001
  43. Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK  et al.  Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients.  Clin Immunol  2023 Jul;252:109634. doi:10.1016/j.clim.2023.109634
  44. Bilaver LA, Wang H, Naidech AM, Luo Y, Das R, Sehgal S, Gupta R  Natural language processing of pediatric progress notes for the identification of food allergy.  J Allergy Clin Immunol Pract  2023 Jul;11(7):2242-2244.e2. doi:10.1016/j.jaip.2023.04.014
  45. Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD  et al.  Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study.  Brain Behav Immun  2023 Jul;111:116-123. doi:10.1016/j.bbi.2023.03.024
  46. Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM  et al.  Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19.  J Clin Invest  2023 Jun 15;133(12). pii:e170682
  47. Li Y, Luo Y  Spatial Transcriptomic Cell-type Deconvolution Using Graph Neural Networks.  bioRxiv  2023 Jun 09;. pii:2023.03.10.532112
  48. Schepart A, Burton A, Durkin L, Fuller A, Charap E, Bhambri R, Ahmad FS  Artificial intelligence-enabled tools in cardiovascular medicine: A survey of current use, perceptions, and challenges.  Cardiovasc Digit Health J  2023 Jun;4(3):101-110. doi:10.1016/j.cvdhj.2023.04.003
  49. Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A  et al.  Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm.  PLoS One  2023;18(5):e0283553. pii:e0283553
  50. Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S  et al.  Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish.  Sci Adv  2023 Apr 28;9(17):eade0631. pii:eade0631

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