Core Facilities

The Biostatistics Collaboration Center (BCC) works with all levels of investigators on the statistical needs of their research, from study design and grant development to interpretation of results and manuscript preparation. 

Note: The BCC’s scope encompasses non-cancer research at Feinberg School of Medicine; Lurie Cancer Center members should contact the Quantitative Data Sciences Core (QDSC).

To contact the BCC or to learn more, visit the Feinberg Research site.

The Center for Advanced Microscopy (CAM) at Northwestern offers state-of-the art imaging and microscopy instrumentation and services for the study of biological processes at the whole animal, tissue, cellular and subcellular levels. CAM is also home to the Nikon Imaging Center.

To contact CAM or to learn more, visit the center website.

The Center for Advanced Molecular Imaging (CAMI) gives users access to imaging modalities ranging from the nanometer scale to whole animal imaging with an emphasis on in vivo imaging. Imaging services can be provided for investigators’ own animal models, or animal models can be supplied by the Developmental Therapeutics Core. 

To contact the center or to learn more, visit the Feinberg Research site.

The Center for Translational Imaging (CTI) is the Department of Radiology’s MRI research facility that is capable of human and animal (rabbit, rat, mouse) MRI. It also provides advanced nuclear imaging capabilities. CTI has the infrastructure and staff to support all types of imaging research studies. 

To contact the center and to learn more, visit the Feinberg Research site.

The Comprehensive Metabolic Core hosts metabolic hormone analytic resources for both human and animal studies.

To contact the core or to learn more, visit the core website.

The Developmental Therapeutics Core (DTC) provides a range of preclinical testing services and assists investigators with drug formulations and initial assessments of drug stability. The DTC also maintains a patient-derived xenograft (PDX) repository with more than 60 tumor models for in vivo testing of therapies against human tumors and a repository with more than 200 human tumor cell lines.

To contact the core or to learn more, visit the core website.

The Northwestern Medicine Enterprise Data Warehouse (NMEDW) is a joint initiative across the Northwestern University Feinberg School of Medicine and Northwestern Memorial Healthcare Corporation. Its mission is to create a single, comprehensive and integrated repository of all clinical and research data sources on the campus to facilitate research, clinical quality, healthcare operations and medical education.

To contact the warehouse or to learn more, visit the Feinberg Research site.

The Immunobiology Flow Cytometry Core trains users and facilitates the use of flow cytometers with a special focus on immunology research.

To contact the core or to learn more, visit the Feinberg Research site.

The Robert H. Lurie Comprehensive Cancer Center Flow Cytometry Core Facility uniquely supports investigators with the entire spectrum of cytometric experiment management, which involves anything from initial consultation on experimental design to the creation of graphics for publication. 

To contact the facility or to learn more, visit the Northwestern Research site.

The Immunotherapy Assessment Core provides root to branch services for dissection of the immune response phenotypically, functionally and transcriptionally either at the single cell or population level.

To contact the core or to learn more, visit the Lurie Cancer Center website.

Services at the Mathews Center for Cellular Therapy (MCCT) encompass both minimally manipulated stem cell transplant products as well as more than minimal manipulated, novel cellular therapy biological products. The MCCT has the scientific and regulatory expertise and the capacity to help investigators bring research findings into clinic with investigational new drug applications (IND) and product manufacturing.

To contact the center or to learn more, visit the Northwestern Medicine website.

The mission of the Metabolomics Core Facility at Robert H. Lurie Comprehensive Cancer Center of Northwestern University is to provide LC-MS based metabolomics and integrative genomics services related to metabolism.

To contact the facility or to learn more, visit the Lurie Cancer Center website.

The Microsurgery Core of the Comprehensive Transplant Center provides high-quality microsurgical services to support all principal investigators in need of small animal surgical models. In addition, the core offers consultations on any issues pertaining to microsurgical techniques in small animal models.

To contact the core and to learn more, visit the Feinberg Research site.

The Mouse Histology & Phenotyping Laboratory assists investigators with tissue histopathology for all rodent species (i.e., mouse, rat, etc.), including phenotyping consultation of organs and tissues, dissection and tissue processing, and one-on-one consultation with investigators.

To contact the lab or to learn more, visit the Feinberg Research site.

The Northwestern University Nervous System Tumor Bank (NSTB) supplies investigators with high-quality, patient-derived biospecimens (tissues, cells, blood and cerebrospinal fluid) to support preclinical and translational neuro-oncology research. The bank includes a comprehensive platform for biospecimen and data banking.

To contact the bank or to learn more, visit the NSTB website.

NUgene Project is a biospecimen repository with longitudinal medical information from nearly 10,000 participating patients at Northwestern-affiliated outpatient clinics and hospitals. The repository provides investigators with coded DNA samples and data for genomics research, as well as a vehicle for participant recruitment and contact for secondary studies.

To contact the project or to learn more, visit the Center for Genetic Medicine website.

The only Northwestern core facility dedicated to next-generation sequencing, the NUSeq Core is equipped with state-of-the-art genomics instrumentation, bioinformatics and technological expertise to support genome and biomedical science.

To contact the core or to learn more, visit the Center for Genetic Medicine website.

The Pathology Core Facility provides histology, immunohistochemistry, molecular analysis and microscopic evaluation services for human tissue-based studies. In addition, the core procures fresh biospecimens for clinical trials and biobanking.

To contact the facility or to learn more, visit the Lurie Cancer Center website.

The Simpson Querrey Institute for BioNanotechnology (SQI) Peptide Synthesis Core is equipped with instrumentation and staff dedicated to the synthesis, purification and analysis of peptides. Staff members provide project consultation and peptide design assistance, custom peptide services and training on open access instrumentation.

To contact the facility or to learn more, visit the SQI website.

The Northwestern Proteomics Core offers multiple types of experiments, from simple protein identification to protein quantitation (both relative and absolute). The core performs both traditional bottom-up proteomics, where proteins are digested with an enzyme prior to analysis, and intact, top-down proteomics analyses. The ability to perform top-down proteomics within the facility distinguishes the core from many other proteomics cores around the world.

To contact the core or to learn more, visit the Proteomics website.

Northwestern Information Technology (NUIT) partners with the research community to develop services and education to meet multidisciplinary research needs, enable faster discovery and foster collaboration among researchers.

To contact the unit or to learn more, visit the NUIT website.

Sanger sequencing is often the technique of choice for projects that need to obtain the nucleotide sequence of individual DNA targets, most typically vector constructs or PCR amplicons. The Sanger Sequencing Core provides access to commercial sequencing services contracted by Feinberg School of Medicine.

To contact the core or to learn more, visit the Feinberg Research site.

The Skin Biology & Disease Resource-Based Center is comprised of an administrative core and three research cores related to cutaneous biology.

To contact the center or to learn more, visit the center website.

The Stem Cell Core Facility specializes in creating custom, patient-derived induced pluripotent stem cells (iPSCs), training in stem cell culture, project consulting, CRISPR gene editing and cell banking.

To contact the facility or to learn more, visit the core website.

The Transgenic & Targeted Mutagenesis Laboratory provides both the facilities and technical expertise needed for the production of genetically engineered mouse lines for investigators.

To contact the lab and to learn more, visit the Center for Genetic Medicine site.