Research
Our goal is to generate human genomics datasets that allow neuroscientists to interrogate the genes and cell types affected by Alzheimer's disease. The success of these efforts will help fill the chasm between our understanding of Alzheimer's disease at the level of genes and their functions, with important clinical applications.
In choosing our research projects, featured below, we prioritize collaboration among research institutions, both domestically and internationally. By facilitating agreements with pharmaceutical and AI industry partners, the center aims to streamline research processes, accelerating the pace at which discoveries become therapeutics. Partnerships with international research groups also bring diverse patient populations into the fold, which is essential for studying the multifaceted factors contributing to Alzheimer's disease.
Flagship Projects
- High-Definition Spatial Transcriptomics to Relate Cellular Changes to Phenotype in AD
- The Impact of Environmental Toxins on Alzheimer’s Disease
- Investigate Intrathecal Immune Changes Associated With Residual Cognitive Decline
- Molecular Assessment of Resiliency to Autosomal Dominant Alzheimer’s Disease
- Molecular Underpinnings of Immunoreactivity in Patients With CAA-RI
- Molecular Mechanisms of Sporadic Early-Onset Alzheimer’s Disease
- Mechanisms of Amyloid Clearance in Vaccinated Alzheimer’s Disease Patients