Participate in a Research Study
The Center for Circadian & Sleep Medicine is focused on clinical research. Learn more about our trials and participation opportunities via the search results for Northwestern Neurology on clinicaltrials.gov. Below is a selected list of our current active protocols.
Feinberg Clinical Trials
Scientists at the medical school are conducting hundreds of clinical trials daily. Learn more about all our work via the Feinberg Office of Research Clinical Trials page. Search below for trials by disease or condition.
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Delayed Sleep-Wake Phase DisorderDelayed Sleep-Wake Phase Disorder (DSWPD) is a Circadian Rhythm disorder that affects millions of people each year representing an important public health issue. Patients with DSWPD have late sleep times and often obtain insufficient sleep during the work/school week due to difficulties falling asleep and awakening at socially … Delayed Sleep-Wake Phase Disorder (DSWPD) is a Circadian Rhythm disorder that affects millions of people each year representing an important public health issue. Patients with DSWPD have late sleep times and often obtain insufficient sleep during the work/school week due to difficulties falling asleep and awakening at socially required times, and patients often present with excessive sleepiness that significantly interferes with daytime activities. The purpose of the study is to understand mechanisms of DSWPD. This study will improve our understanding of circadian rhythms in humans and may help us to create treatments and strategies for DSWPD. Copy Study URL to Clipboard Copy |
Long COVID and daytime sleepinessResearchers are studying possible treatments for adults who have Long COVID, which is when a person has symptoms months after getting COVID. We want to better understand how the virus that causes COVID-19 affects sleep and find possible treatments to improve sleep quality and daily functioning for people who … Researchers are studying possible treatments for adults who have Long COVID, which is when a person has symptoms months after getting COVID. We want to better understand how the virus that causes COVID-19 affects sleep and find possible treatments to improve sleep quality and daily functioning for people who have Long COVID. Eligibility Criteria You are an adult who had COVID • You do not have an active COVID infection • You still have 1 or more of these symptoms: – Problems falling asleep or staying asleep – Poor sleep quality – Trouble staying awake or feeling very tired during the day – Insomnia or problems with your sleep-wake schedule • You are not pregnant or breastfeeding Location(s)
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Stress System Regulation in InsomniaInsomnia disorder is common among older adults and is associated with an increased risk of developing cognitive impairment. However, the nature of this association is not well understood. The purpose of this research is to examine the relationship that links physiological arousal (the stress system) with sleep and cognitive function … Insomnia disorder is common among older adults and is associated with an increased risk of developing cognitive impairment. However, the nature of this association is not well understood. The purpose of this research is to examine the relationship that links physiological arousal (the stress system) with sleep and cognitive function in older adults with insomnia and good sleeper controls. Eligibility Criteria People 55 years and older with 1) chronic insomnia (trouble falling asleep or staying asleep) or 2) good sleepers. Exclusion criteria include: 1) Sleep disorders other than insomnia; 2) Habitual bedtime before 9pm or morning awakening before 5am; 3) History of neurological disorders; 4) History of psychiatric disorders (e.g., depression, anxiety); 5) Cognitive impairment; 6) Diabetes; 7) Current, or use within the past month, of psychoactive, hypnotic, stimulant or analgesic medications (except occasionally); 8) Use of Beta-blockers 9) Hormone replacement therapy; 10) Shift work or other types of self-imposed irregular sleep schedules. Location(s)
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