Research

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Active Studies
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Participate in a Research Study

The Center for Circadian & Sleep Medicine is focused on clinical research. Learn more about our trials and participation opportunities via the search results for Northwestern Neurology on clinicaltrials.gov. Below is a selected list of our current active protocols.

Feinberg Clinical Trials

Scientists at the medical school are conducting hundreds of clinical trials daily. Learn more about all our work via the Feinberg Office of Research Clinical Trials page. Search below for trials by disease or condition.

Search Studies

Trials
Stress System Regulation in Insomnia Insomnia disorder is common among older adults and is associated with an increased risk of developing cognitive impairment. However, the nature of this association is not well understood. The purpose of this research is to examine the relationship that links physiological arousal (the stress system) with sleep and cognitive function … Insomnia disorder is common among older adults and is associated with an increased risk of developing cognitive impairment. However, the nature of this association is not well understood. The purpose of this research is to examine the relationship that links physiological arousal (the stress system) with sleep and cognitive function in older adults with insomnia and good sleeper controls. Eligibility Criteria People 55 years and older with 1) chronic insomnia (trouble falling asleep or staying asleep) or 2) good sleepers. Exclusion criteria include: 1) Sleep disorders other than insomnia; 2) Habitual bedtime before 9pm or morning awakening before 5am; 3) History of neurological disorders; 4) History of psychiatric disorders (e.g., depression, anxiety); 5) Cognitive impairment; 6) Diabetes; 7) Current, or use within the past month, of psychoactive, hypnotic, stimulant or analgesic medications (except occasionally); 8) Use of Beta-blockers 9) Hormone replacement therapy; 10) Shift work or other types of self-imposed irregular sleep schedules. Principal Investigator Zee, Phyllis C Location(s) Map it 201 E. Huron St. Chicago, IL IRB number STU00219832 More Info Keywords insomnia sleep cognition light norepinephrine stress system older adults Copy Study URL to Clipboard Copy

Trials

Stress System Regulation in Insomnia

Insomnia disorder is common among older adults and is associated with an increased risk of developing cognitive impairment. However, the nature of this association is not well understood. The purpose of this research is to examine the relationship that links physiological arousal (the stress system) with sleep and cognitive function …

Eligibility Criteria

People 55 years and older with 1) chronic insomnia (trouble falling asleep or staying asleep) or 2) good sleepers.

Exclusion criteria include:

1) Sleep disorders other than insomnia;

2) Habitual bedtime before 9pm or morning awakening before 5am;

3) History of neurological disorders;

4) History of psychiatric disorders (e.g., depression, anxiety);

5) Cognitive impairment;

6) Diabetes;

7) Current, or use within the past month, of psychoactive, hypnotic, stimulant or analgesic medications (except occasionally);

8) Use of Beta-blockers

9) Hormone replacement therapy;