Center for Advanced Microscopy

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Mission

The Center for Advanced Microscopy (CAM) offers state-of-the art instrumentation and services for the study of biological processes at the whole animal, tissue, cellular, and subcellular levels. The center’s services include confocal microscopy, multiphoton imaging, super-resolution microscopy (SIM & STORM), microinjection, ratiometric calcium imaging, laser microdissection, high content imaging, whole animal bioluminescent and fluorescent imaging, atomic force microscopy, transmission electron microscopy, platinum replica electron microscopy, and scanning electron microscopy.

Services Offered

• Training and technical support for intravital, light and electron microscopy
• Preparation of samples for light or electron microscopy
• Data Analysis Services including AI support

Equipment Available

The Center for Advanced Microscopy is located on the second floors of the adjoining Searle and Morton buildings. It consists of a 16-room suite that occupies approximately 5300 sf. Within the facility, there are two "wet" laboratory rooms with fume hoods, one specifically for EM sample preparation, and one available for users who need immediate laboratory set-up to complete their time-dependent imaging experiments.

Light Microscopy

• Bruker/JPK  NanoWizard Atomic Force Microscope with Nikon A1R Confocal
• ImageXpress HT.ai Confocal with Automated Liquid Dispensing
• LaVision UltraMicroscope 2 Lightsheet System
• Leica SP8 DiveB Multiphoton
• Nikon AXR Confocal Microscope (2)
• Nikon AZ-100 Multi-purpose Zoom Microscope
• Nikon A1R Laser Scanning Confocal Microscopes (2)
• Nikon A1 Laser Scanning Confocal Microscopes
• Nikon Biostation IM-Q Live Cell Imaging Microscopes (2)
• Nikon Biostation CT High Content Live Cell Imaging Microscope
• Nikon AZ100/C2 Macro Laser Scanning Confocal Microscope
• Nikon A1R-MP Multiphoton Microscope
• Nikon N-SIM Structured Illumination Super-resolution Microscope
• Nikon Ti2 Epi-fluorescence Microscope (2)
• Nikon STochastic Optical Reconstruction Microscopy (STORM)
• Nikon/Yokogawa W1 SoRa Super Resolution Spinning Disk Confocal Microscope
• Nikon/Yokogawa W1 Spinning Disk Confocal Microscope
• Spectral Imaging Instruments LAGO Bioluminescent and Fluorescent Imaging System
• TissueGnostics Tissue Cytometer
• Zeiss PALM Laser Catapulting Microdissection System

• Dissecting and light microscopes
• FEI Tecnai Spirit G2 transmission electron microscope with 3D tomography capability
• JEOL NeoScope benchtop Scanning Electron Microscope (SEM)
• Leica EM ACE600 coater
• Leica EM CPC plunge freezer
• Leica EM Automatic Freeze Substitution System
• Leica Ultracut UC6 ultramicrotome
• Leica Ultracut UC7 ultramicrotome
• One LKB 7800 knifemaker
• Ovens for curing resin blocks
• Tousimis Samdri 790 critical point dyer

Other

• FlexCell Fx-6000T Tension System
• Ultimaker 5s 3D Printer