Microsurgery and Preclinical Research Core
Mission
The mission of the Comprehensive Transplant Center (CTC) Microsurgery Core is to provide comprehensive microsurgery services for basic and preclinical animal research. We offer a variety of acute and chronic surgical models and companion blood gas/chemistry assays for use in mechanistic studies and drug discovery. Our microsurgeons have extensive experience in performing sophisticated surgical procedures, such as vascularized organ transplantation in rodents, and are available to assist in the creation of the most innovative in vivo animal models. In addition, we offer technical training and consultations on any issues pertaining to microsurgical techniques.
Services Offered
Surgical Models- Kidney transplantation
- Liver transplantation
- Skin transplantation
- Aortic transplantation
- Cardiac transplantation
- Lung transplant
- Short bowel syndrome
- Organ ischemic/reperfusion models (hepatic, renal, intestinal )
- Thymectomy
- Model of arterial malformation
- Carotid balloon injury models
- Cardiac injury models
- 5/6 Nephrectomy
- Unilateral ureteral obstruction
- Carotid Artery Surgery
- Parabiosis models
- Islet isolation and transplantation
- Drug deliveries (including intravenous and intracecal injections)
- Serial blood collections (retro-orbital or tail vein, cardiac picture)
- Blood gas and chemistry assays (hepatic, renal, hormone)
Request form is available here
Acknowledgement
All manuscripts and grants presenting work supported by this core should include the following acknowledgement:
"All microsurgical procedures and/or blood chemistry tests were performed by the Microsurgery and Preclinical Research Core at Northwestern University Comprehensive Transplant Center "