Northwestern University Proteomics Core

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Mission

The mission of Northwestern Proteomics is to develop new proteomics technologies; to apply them to timely questions in basic, translational, and clinical research; to educate researchers throughout the Chicagoland area; and to communicate our research findings to the wider scientific community.

We're committed to providing the best proteomics research on a budget. As scientists, we’ll review each project and provide consultation to manage everyone's expectations and ensure the experiment has the best chance of success. Mass spectrometry based-proteomics is not a simple technique so we're both a University Research Center and a service-oriented core which handles projects of all sizes.

Within the Northwestern Proteomics core, we offer several analytical approaches including bottom-up proteomics for identification and quantitation (where proteins are digested with an enzyme prior to analysis); histone mark analysis via our Epiproteomic Histone Modification Panel; and top-down proteomics which distinguishes us globally from many other proteomics cores.

How do you start work with us?

If it's your first-time performing mass spectrometry-based proteomics, email us at proteomics@northwestern.edu to arrange a meeting. We can discuss your project, answer any initial questions, and provide guidance for the best path forward.

If you've worked with us before and already know what you wish to do, you should request a sample submission form by emailing proteomics@northwestern.edu. You should complete this form and then create an order through NUcore ("Place an Order" button above) where you will upload the completed form. The final step in the process will be for you to submit your samples at either of our drop-off locations (listed below) between 8:30 a.m. and 5:00 p.m., Monday through Friday.

Services Offered

• Protein identification
• Protein quantitation by label-free and labeled techniques (SILAC and TMT)
• Epiproteomic Histone Modification Panel
• Post-translation modifications (PTMs) including phosphoproteomics
• Top-down proteomics

Documents

• Rates