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High-Impact Factor Research 2023
Are C, Murthy SS, Sullivan R, Schissel M, Chowdhury S, Alatise O, Anaya D, Are M, Balch C, Bartlett D, Brennan M, Cairncross L, Clark M, Deo SVS, Dudeja V, D'Ugo D, Fadhil I, Giuliano A, Gopal S, Gutnik L, Ilbawi A, Jani P, Kingham TP, Lorenzon L, Leiphrakpam P, Leon A, Martinez-Said H, McMasters K, Meltzer DO, Mutebi M, Zafar SN, Naik V, Newman L, Oliveira AF, Park DJ, Pramesh CS, Rao S , Subramanyeshwar Rao T, Bargallo-Rocha E, Romanoff A, Rositch AF, Rubio IT, Salvador de Castro Ribeiro H, Sbaity E, Senthil M, Smith L, Toi M, Turaga K, Yanala U, Yip CH, Zaghloul A, Anderson BO. Global Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide . The Lancet. Oncology . 2023; 24(12):e472-e518.
Barefield DY , Tonino P, Woulfe KC, Rahmanseresht S, O'Leary TS, Burnham HV, Wasserstrom JA , Kirk JA, Previs MJ, Granzier HL, McNally EM . Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes . Proceedings of the National Academy of Sciences of the United States of America . 2023; 120(51):e2314920120-e2314920120.Bernstein RA , Kamel H, Granger CB, Piccini JP, Katz JM, Sethi PP, Pouliot E, Franco N, Ziegler PD, Schwamm LH. Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease: 3-Year Results From the STROKE AF Randomized Clinical Trial . JAMA Neurology . 2023; 80(12):1277-1283.Borna Š, Lee E, Nideffer J, Ramachandran A, Wang B, Baker J, Mavers M, Lakshmanan U, Narula M, Garrett AK, Schulze J, Olek S, Marois L, Gernez Y, Bhatia M, Chong HJ, Walter J, Kitcharoensakkul M, Lang A , Cooper MA, Bertaina A, Roncarolo MG, Meffre E, Bacchetta R. Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with <i>FOXP3</i> mutations . Science Translational Medicine . 2023; 15(727):eadg6822-eadg6822.
Chen WC, Choudhury A, Youngblood MW , Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC, Harmanci AS, Harmanci AO, Klisch TJ, Nguyen MP, Vasudevan HN, McCortney K , Yu TJ, Bhave V, Lam TC, Pu JK, Li LF, Leung GK, Chan JW, Perlow HK, Palmer JD, Haberler C, Berghoff AS, Preusser M, Nicolaides TP, Mawrin C, Agnihotri S, Resnick A, Rood BR, Chew J, Young JS, Boreta L, Braunstein SE, Schulte J, Butowski N, Santagata S, Spetzler D, Bush NAO, Villanueva-Meyer JE, Chandler JP , Solomon DA, Rogers CL, Pugh SL, Mehta MP, Sneed PK, Berger MS, Horbinski CM , McDermott MW, Perry A, Bi WL, Patel AJ, Sahm F, Magill ST , Raleigh DR. Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses . Nature Medicine . 2023; 29(12):3067-3076.
Dominguez A , Iruela-Arispe ML . Integration of Chemo-mechanical signaling in response to fluid shear stress by the endothelium . Current Opinion in Cell Biology . 2023; 85():102232-102232.Fares J , Petrosyan E , Kanojia D , Dmello C , Cordero A , Duffy JT , Yeeravalli R , Sahani MH, Zhang P , Rashidi A , Arrieta VA , Ulasov I , Ahmed AU , Miska J , Balyasnikova IV , James CD , Sonabend AM , Heimberger AB , Lesniak MS . Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases . The Journal of Clinical Investigation . 2023; 133(24).Gupta DK, Lewis CE, Varady KA, Su YR, Madhur MS, Lackland DT, Reis JP, Wang TJ, Lloyd-Jones DM , Allen NB . Effect of Dietary Sodium on Blood Pressure: A Crossover Trial . JAMA . 2023; 330(23):2258-2266.
Kahan BC, Hall SS, Beller EM, Birchenall M, Chan AW, Elbourne D, Little P, Fletcher J, Golub RM , Goulao B, Hopewell S, Islam N, Zwarenstein M, Juszczak E, Montgomery AA. Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement . JAMA . 2023; 330(21):2106-2114.
Khan SS , Grobman WA, Cameron NA . Cardiovascular Health in the Postpartum Period . Kochan TJ , Nozick SH , Valdes A , Mitra SD , Cheung BH , Lebrun-Corbin M , Medernach RL , Vessely MB , Mills JO , Axline CMR , Nelson JA , VanGosen EM , Ward TJ , Ozer EA , van Duin D, Chen L, Kreiswirth BN, Long SW, Musser JM, Bulman ZP, Wunderink RG , Hauser AR . Klebsiella pneumoniae clinical isolates with features of both multidrug-resistance and hypervirulence have unexpectedly low virulence . Nature Communications . 2023; 14(1):7962-7962.Leiding JW, Arnold DE, Parikh S, Logan B, Marsh RA, Griffith LM, Wu R, Kidd S, Mallhi K, Chellapandian D, Si Lim SJ, Grunebaum E, Falcone EL, Murguia-Favela L, Grossman D, Prasad VK, Heimall JR, Touzot F, Burroughs LM, Bleesing J, Kapoor N, Dara J, Williams O , Kapadia M, Oshrine BR, Bednarski JJ, Rayes A, Chong H, Cuvelier GDE, Forbes Satter LR, Martinez C, Vander Lugt MT, Yu LC, Chandrakasan S, Joshi A, Prockop SE, Dávila Saldaña BJ, Aquino V, Broglie LA, Ebens CL, Madden LM, DeSantes K, Milner J, Rangarajan HG, Shah AJ, Gillio AP, Knutsen AP, Miller HK, Moore TB, Graham P, Bauchat A, Bunin NJ, Teira P, Petrovic A, Chandra S, Abdel-Azim H, Dorsey MJ, Birbrayer O, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson TR, Malech HL, Kang EM. Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD . Blood . 2023; 142(24):2105-2118.
Leisten ED , Woods AC , Wong YC . Super-resolution microscopy: Insights into mitochondria-lysosome crosstalk in health and disease . The Journal of Cell Biology . 2023; 222(12).Lincoff AM , Brown-Frandsen K , Colhoun HM , Deanfield J , Emerson SS , Esbjerg S , Hardt-Lindberg S , Hovingh GK , Kahn SE , Kushner RF , Lingvay I , Oral TK , Michelsen MM , Plutzky J , Tornøe CW , Ryan DH . Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes . The New England Journal of Medicine . 2023; 389(24):2221-2232.Madan RA, Karzai F, VanderWeele DJ , Cheng HH, de Bono JS. Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits . Journal of Clinical Oncology . 2023; 41(36):5501-5504.
Moehler M, Xiao H, Blum SI, Elimova E, Cella D , Shitara K, Ajani JA, Janjigian YY, Garrido M, Shen L, Yamaguchi K, Liu T, Schenker M, Kowalyszyn R, Bragagnoli AC, Bruges R, Montesarchio V, Pazo-Cid R, Hunter S, Davenport E, Wang J, Kondo K, Li M, Wyrwicz L. Health-Related Quality of Life With Nivolumab Plus Chemotherapy Versus Chemotherapy in Patients With Advanced Gastric/Gastroesophageal Junction Cancer or Esophageal Adenocarcinoma From CheckMate 649 . Journal of Clinical Oncology . 2023; 41(35):5388-5399.
Ostrominski JW, Vaduganathan M, Selvaraj S, Claggett BL, Miao ZM, Desai AS, Jhund PS, Kosiborod MN, Lam CSP, Inzucchi SE, Martinez FA, de Boer RA, Hernandez AF, Shah SJ , Petersson M, Maria Langkilde A, McMurray JJV, Solomon SD. Dapagliflozin and Apparent Treatment-Resistant Hypertension in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: The DELIVER Trial .
Peters MA, Cloete K, Odwe G, Tadele G, Hirschhorn LR , Magge H, Roder-DeWan S. Embedding implementation research to cross the quality of care chasm during the covid-19 pandemic and beyond . BMJ . 2023; 383():e076331-e076331.
Petersen RC, Weintraub S , Sabbagh M, Karlawish J, Adler CH, Dilworth-Anderson P, Frank L, Huling Hummel C, Taylor A. A New Framework for Dementia Nomenclature . JAMA Neurology . 2023; 80(12):1364-1370.
Seo YD, Lu H, Black G, Smythe K, Yu Y, Hsu C, Ng J , Hermida de Viveiros P , Warren EH, Schroeder BA, O'Malley RB, Cranmer LD, Loggers ET, Wagner MJ, Bonham L, Pillarisetty VG, Kane G, Berglund P, Hsu FJ, Mi X , Alexiev BA , Pierce RH, Riddell SR, Jones RL, Ter Meulen J, Kim EY, Pollack SM . Toll-Like Receptor 4 Agonist Injection With Concurrent Radiotherapy in Patients With Metastatic Soft Tissue Sarcoma: A Phase 1 Nonrandomized Controlled Trial . JAMA Oncology . 2023; 9(12):1660-1668.
Smolgovsky S, Bayer AL, Kaur K, Sanders E, Aronovitz M, Filipp ME , Thorp EB , Schiattarella GG, Hill JA, Blanton RM, Cubillos-Ruiz JR, Alcaide P. Impaired T cell IRE1α/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction . The Journal of Clinical Investigation . 2023; 133(24).
Song P , Peng W , Sauve V, Fakih R, Xie Z , Ysselstein D , Krainc T , Wong YC , Mencacci NE , Savas JN , Surmeier DJ , Gehring K, Krainc D . Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons . Neuron . 2023; 111(23):3775-3788.e7.Wang S , Iyer R , Han X, Wei J , Li N, Cheng Y , Zhou Y, Gao Q , Zhang L, Yan M , Sun Z, Fang D . CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion . The Journal of Clinical Investigation . 2023; 133(23).Yoo JY , Oh S, Shalish W, Maeng WY , Cerier E , Jeanne E, Chung MK, Lv S, Wu Y , Yoo S , Tzavelis A , Trueb J , Park M, Jeong H, Okunzuwa E , Smilkova S , Kim G, Kim J, Chung G, Park Y, Banks A , Xu S , Sant'Anna GM, Weese-Mayer DE , Bharat A , Rogers JA . Wireless broadband acousto-mechanical sensing system for continuous physiological monitoring. Nature Medicine . 2023; 29(12):3137-3148.Yu HA, Goto Y, Hayashi H, Felip E, Chih-Hsin Yang J, Reck M, Yoh K, Lee SH, Paz-Ares L, Besse B, Bironzo P, Kim DW, Johnson ML, Wu YL, John T, Kao S, Kozuki T, Massarelli E, Patel J , Smit E, Reckamp KL, Dong Q, Shrestha P, Fan PD, Patel P, Sporchia A, Sternberg DW, Sellami D, Jänne PA. HERTHENA-Lung01, a Phase II Trial of Patritumab Deruxtecan (HER3-DXd) in Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer After Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Platinum-Based Chemotherapy . Journal of Clinical Oncology . 2023; 41(35):5363-5375.
Zhao Z , Aoi Y , Philips CN , Meghani KA , Gold SR , Yu Y , John LS , Qian J , Zeidner JM , Meeks JJ , Shilatifard A . Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment . Proceedings of the National Academy of Sciences of the United States of America . 2023; 120(52):e2310063120-e2310063120.
Adams JRG, Pooranachithra M, Jyo EM, Zheng SL, Goncharov A, Crew JR , Kramer JM , Jin Y, Ernst AM, Chisholm AD. Nanoscale patterning of collagens in C. elegans apical extracellular matrix . Nature Communications . 2023;14(1):7506.
Aoi Y, Shilatifard A . Transcriptional elongation control in developmental gene expression, aging, and disease . Molecular Cell . 2023;83(22):3972-3999.Benotmane JK, Kueckelhaus J, Will P, Zhang J, Ravi VM, Joseph K, Sankowski R, Beck J, Lee-Chang C , Schnell O, Heiland DH . High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq . Nature Communications . 2023;14(1):7432.
Breault MS, Sacré P, Fitzgerald ZB , Gale JT, Cullen KE, González-Martínez JA, Sarma SV. Internal states as a source of subject-dependent movement variability are represented by large-scale brain networks . Nature Communications . 2023;14(1):7837.
Burks HE , Pokorny JL , Koetsier JL , Roth-Carter QR , Arnette CR , Gerami P , Seykora JT, Johnson JL , Ren Z , Green KJ . Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration . Journal of Cell Biology . 2023;222(11).Burton A, Wang Z , Song D , Tran S , Hanna J, Ahmad D, Bakall J, Clausen D, Anderson J, Peralta R, Sandepudi K , Benedetto A , Yang E , Basrai D , Miller LE , Tresch MC , Gutruf P. Fully implanted battery-free high power platform for chronic spinal and muscular functional electrical stimulation . Nature Communications . 2023;14(1):7887.
Chatur S, Vaduganathan M, Claggett BL, Cunningham JW, Docherty KF, Desai AS, Jhund PS, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN, Lam CSP, Martinez FA, Shah SJ , Petersson M, Langkilde AM, McMurray JJV, Solomon SD. Outpatient Worsening Among Patients With Mildly Reduced and Preserved Ejection Fraction Heart Failure in the DELIVER Trial . Circulation . 2023;148(22):1735-1745.
Darst BF, Saunders E, Dadaev T, Sheng X, Wan P, Pooler L, Xia LY, Chanock S, Berndt SI, Wang Y, Patel AV, Albanes D, Weinstein SJ, Gnanapragasam V, Huff C, Couch FJ, Wolk A, Giles GG, Nguyen-Dumont T, Milne RL, Pomerantz MM, Schmidt JA, Travis RC, Key TJ, Stopsack KH, Mucci LA, Catalona WJ , Marosy B, Hetrick KN, Doheny KF, MacInnis RJ, Southey MC, Eeles RA, Wiklund F, Conti DV, Kote-Jarai Z, Haiman CA. Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer . JAMA Oncology . 2023;9(11):1514-1524.
Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL, Lim TY, Appel GB, Huggins K, Liu L, Mitrotti A, Stangl MC, Bomback A, Westland R, Bodria M, Marasa M, Shang N, Cohen DJ, Crew RJ, Morello W, Canetta P, Radhakrishnan J, Martino J, Liu Q, Chung WK, Espinoza A , Luo Y , Wei WQ, Feng Q, Weng C, Fang Y, Kullo IJ, Naderian M, Limdi N, Irvin MR, Tiwari H, Mohan S, Rao M, Dube GK, Chaudhary NS, Gutiérrez OM, Judd SE, Cushman M, Lange LA, Lange EM, Bivona DL, Verbitsky M, Winkler CA, Kopp JB, Santoriello D, Batal I, Pinheiro SVB, Oliveira EA, Simoes E Silva AC, Pisani I, Fiaccadori E, Lin F, Gesualdo L, Amoroso A, Ghiggeri GM, D'Agati VD, Magistroni R, Kenny EE, Loos RJF, Montini G, Hildebrandt F, Paul DS, Petrovski S, Goldstein DB, Kretzler M, Gbadegesin R, Gharavi AG, Kiryluk K, Sampson MG, Pollak MR, Sanna-Cherchi S. Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease . Nature Communications . 2023;14(1):7836.
Howerton E, Contamin L, Mullany LC, Qin M, Reich NG, Bents S, Borchering RK, Jung SM, Loo SL, Smith CP, Levander J, Kerr J, Espino J, van Panhuis WG, Hochheiser H, Galanti M, Yamana T, Pei S, Shaman J, Rainwater-Lovett K, Kinsey M, Tallaksen K, Wilson S, Shin L, Lemaitre JC, Kaminsky J, Hulse JD, Lee EC, McKee CD, Hill A, Karlen D, Chinazzi M, Davis JT, Mu K, Xiong X, Pastore Y Piontti A, Vespignani A, Rosenstrom ET, Ivy JS, Mayorga ME, Swann JL, España G, Cavany S, Moore S, Perkins A, Hladish T, Pillai A, Ben Toh K , Longini I, Chen S, Paul R, Janies D, Thill JC, Bouchnita A, Bi K, Lachmann M, Fox SJ, Meyers LA, Srivastava A, Porebski P, Venkatramanan S, Adiga A, Lewis B, Klahn B, Outten J, Hurt B, Chen J, Mortveit H, Wilson A, Marathe M, Hoops S, Bhattacharya P, Machi D, Cadwell BL, Healy JM, Slayton RB, Johansson MA, Biggerstaff M, Truelove S, Runge MC, Shea K, Viboud C, Lessler J. Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty . Nature Communications . 2023;14(1):7260.
Jouandet GC, Alpert MH, Simões JM, Suhendra R, Frank DD, Levy JI, Para A, Kath WL, Gallio M. Rapid threat assessment in the Drosophila thermosensory system . Nature Communications . 2023;14(1):7067.Lau ES, Roshandelpoor A, Zarbafian S, Wang D, Guseh JS, Allen N , Varadarajan V, Nayor M, Shah RV, Lima JAC, Shah SJ , Yu B, Alotaibi M, Cheng S, Jain M, Lewis GD, Ho JE. Eicosanoid and eicosanoid-related inflammatory mediators and exercise intolerance in heart failure with preserved ejection fraction . Nature Communications . 2023;14(1):7557.
Luján MÁ, Covey DP, Young-Morrison R, Zhang L, Kim A, Morgado F, Patel S , Bass CE, Paladini C, Cheer JF. Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction . Nature Communications . 2023;14(1):7545.
Mack MJ , Leon MB , Thourani VH , Pibarot P , Hahn RT , Genereux P , Kodali SK , Kapadia SR , Cohen DJ , Pocock SJ , Lu M , White R , Szerlip M , Ternacle J , Malaisrie SC , Herrmann HC , Szeto WY , Russo MJ , Babaliaros V , Smith CR , Blanke P , Webb JG , Makkar R. Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years. New England Journal of Medicine . 2023;389(21):1949-1960.McIntosh CM, Allocco JB, Wang P, McKeague ML, Cassano A, Wang Y, Xie SZ, Hynes G, Mora-Cartín R, Abbondanza D, Chen L, Sattar H, Yin D, Zhang ZJ , Chong AS, Alegre ML. Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection . Journal of Clinical Investigation . 2023;133(21).
Meade N, Toreev HK, Chakrabarty RP, Hesser CR, Park C, Chandel NS, Walsh D. The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses . Nature Communications . 2023;14(1):7889.Miller N , Xu Z , Quinlan KA , Ji A , McGivern JV, Feng Z, Shi H , Ko CP, Tsai LH, Heckman CJ , Ebert AD, Ma YC. Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(47):e2300308120.Morgan MAJ , Mohammad Parast S , Iwanaszko M , Aoi Y , Yoo D, Dumar ZJ , Howard BC , Helmin KA , Liu Q , Thakur WR , Zeidner JM , Singer BD , Eichler EE, Shilatifard A. . ELOA3: A primate-specific RNA polymerase II elongation factor encoded by a tandem repeat gene cluster . Science Advances . 2023;9(47):eadj1261.O'Leary KJ , Johnson JK , Williams MV, Estrella R, Hanrahan K, Leykum LK, Smith GR , Goldstein JD, Kim JS , Thompson S, Terwilliger I , Song J , Lee J , Manojlovich M. Effect of Complementary Interventions to Redesign Care on Teamwork and Quality for Hospitalized Medical Patients : A Pragmatic Controlled Trial . Annals of Internal Medicine . 2023;176(11):1456-1464.Ortega JA , Sasselli IR , Boccitto M, Fleming AC , Fortuna TR, Li Y, Sato K , Clemons TD , Mckenna ED , Nguyen TP , Anderson EN, Asin J, Ichida JK, Pandey UB, Wolin SL, Stupp SI , Kiskinis E. CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology . Science Advances . 2023;9(45):eadf7997.Safaie M, Chang JC, Park J, Miller LE , Dudman JT, Perich MG, Gallego JA. Preserved neural dynamics across animals performing similar behaviour . Nature . 2023;623(7988):765-771.
Shelchkova ND, Downey JE, Greenspon CM, Okorokova EV, Sobinov AR, Verbaarschot C, He Q, Sponheim C, Tortolani AF, Moore DD, Kaufman MT, Lee RC, Satzer D, Gonzalez-Martinez J, Warnke PC, Miller LE , Boninger ML, Gaunt RA, Collinger JL, Hatsopoulos NG, Bensmaia SJ. Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex . Nature Communications . 2023;14(1):7270.
Stanczyk PJ, Tatekoshi Y, Shapiro JS, Nayudu K, Chen Y, Zilber Z, Schipma M, De Jesus A, Mahmoodzadeh A, Akrami A, Chang HC, Ardehali H. DNA Damage and Nuclear Morphological Changes in Cardiac Hypertrophy Are Mediated by SNRK Through Actin Depolymerization . Circulation . 2023;148(20):1582-1592. Stroup EK, Ji Z. Deep learning of human polyadenylation sites at nucleotide resolution reveals molecular determinants of site usage and relevance in disease . Nature Communications . 2023;14(1):7378.Sun Z, Zhang Z, Banu K, Gibson IW, Colvin RB, Yi Z, Zhang W, De Kumar B, Reghuvaran A, Pell J, Manes TD, Djamali A, Gallon L , O'Connell PJ, He JC, Pober JS, Heeger PS, Menon MC. Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival . Journal of Clinical Investigation . 2023;133(21).
Wadden TA, Chao AM, Machineni S, Kushner R, Ard J, Srivastava G, Halpern B, Zhang S, Chen J, Bunck MC, Ahmad NN, Forrester T. Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial . Nature Medicine . 2023;29(11):2909-2918.
Wen PY, van den Bent M, Youssef G, Cloughesy TF, Ellingson BM, Weller M, Galanis E, Barboriak DP, de Groot J, Gilbert MR, Huang R, Lassman AB, Mehta M, Molinaro AM, Preusser M, Rahman R, Shankar LK, Stupp R , Villanueva-Meyer JE, Wick W, Macdonald DR, Reardon DA, Vogelbaum MA, Chang SM. RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults . Journal of Clinical Oncology . 2023;41(33):5187-5199.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM , Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, , Moreland LW, Goodman SM, Perlman H , Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes . Nature . 2023;623(7987):616-624.
Azcorra M, Gaertner Z, Davidson C, He Q, Kim H, Nagappan S, Hayes CK , Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Longnecker R, Awatramani R, Dombeck DA. Unique functional responses differentially map onto genetic subtypes of dopamine neurons . Nature Neuroscience . 2023;26(10):1762-1774.Blinder VS, Deal AM, Ginos B, Jansen J, Dueck AC, Mazza GL, Henson S, Carr P, Rogak LJ, Weiss A, Rapperport A, Jonsson M, Spears PA, Cella D , Gany F, Schrag D, Basch E. Financial Toxicity Monitoring in a Randomized Controlled Trial of Patient-Reported Outcomes During Cancer Treatment (Alliance AFT-39). Journal of Clinical Oncology . 2023;41(29):4652.
Bramante CT, Buse JB, Liebovitz DM , Nicklas JM, Puskarich MA, Cohen K, Belani HK, Anderson BJ, Huling JD, Tignanelli CJ, Thompson JL, Pullen M, Wirtz EL, Siegel LK, Proper JL, Odde DJ, Klatt NR, Sherwood NE, Lindberg SM, Karger AB, Beckman KB, Erickson SM, Fenno SL, Hartman KM, Rose MR, Mehta T, Patel B, Griffiths G, Bhat NS, Murray TA, Boulware DR. Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial . Lancet Infectious Diseases . 2023;23(10):1119-1129.
Cao Y, Liu H, Lu SS, Jones KA, Govind AP, Jeyifous O, Simmons CQ, Tabatabaei N, Green WN, Holder JL, Jr., Tahmasebi S, George AL, Jr., Dickinson BC. RNA-based translation activators for targeted gene upregulation . Nature Communications . 2023;14(1):6827.
Carlson LE, Ismaila N, Addington EL, Asher GN, Atreya C, Balneaves LG, Bradt J, Fuller-Shavel N, Goodman J, Hoffman CJ, Huston A, Mehta A, Paller CJ, Richardson K, Seely D, Siwik CJ, Temel JS, Rowland JH. Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology-ASCO Guideline . Journal of Clinical Oncology . 2023;41(28):4562-4591.
Chen PW. TFPI2 is key for cancer stem cell-microglia symbiosis in glioblastoma . Nature Immunology . 2023;24(10):1612-1613.Choi W, Nensel AK, Droho S, Fattah MA, Mokashi-Punekar S, Swygart DI, Burton ST, Schwartz GW, Lavine JA, Gianneschi NC. Thrombospondin-1 proteomimetic polymers exhibit anti-angiogenic activity in a neovascular age-related macular degeneration mouse model . Science Advances . 2023;9(41):eadi8534.
DeWolf S, Tallman MS , Rowe JM, Salman MY. What Influences the Decision to Proceed to Transplant for Patients With AML in First Remission? Journal of Clinical Oncology . 2023;41(29):4693.
Fu T, Sullivan DP, Gonzalez AM, Haynes ME, Dalal PJ, Rutledge NS, Tierney AL, Yescas JA, Weber EW, Muller WA . Mechanotransduction via endothelial adhesion molecule CD31 initiates transmigration and reveals a role for VEGFR2 in diapedesis . Immunity . 2023;56(10):2311-2324.e6.Gunduz-Cinar O, Castillo LI, Xia M, Van Leer E, Brockway ET, Pollack GA, Yasmin F, Bukalo O, Limoges A, Oreizi-Esfahani S, Kondev V, Báldi R, Dong A, Harvey-White J, Cinar R, Kunos G, Li Y, Zweifel LS, Patel S, Holmes A. A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction . Neuron . 2023;111(19):3053-3067.e10.
Han S, Budinger GRS , Gottardi CJ. Alveolar epithelial regeneration in the aging lung . Journal of Clinical Investigation . 2023;133(20).
Jenssen BP, Schnoll R, Beidas RS , Bekelman J, Bauer AM, Evers-Casey S, Fisher T, Scott C, Nicoloso J, Gabriel P, Asch DA, Buttenheim AM, Chen J, Melo J, Grant D, Horst M, Oyer R, Shulman LN, Clifton ABW, Lieberman A, Salam T, Rendle KA, Chaiyachati KH, Shelton RC, Fayanju O, Wileyto EP, Ware S, Blumenthal D, Ragusano D, Leone FT. Cluster Randomized Pragmatic Clinical Trial Testing Behavioral Economic Implementation Strategies to Improve Tobacco Treatment for Patients With Cancer Who Smoke. Journal of Clinical Oncology . 2023;41(28):4511-4521.
Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X, Chen Y, Khatun A, Alson D, Wu Y, Burns R, Lin CW, Kudek MR, Sun J, Cui W . A spatial sequencing atlas of age-induced changes in the lung during influenza infection . Nature Communications . 2023;14(1):6597.
Labouesse MA, Torres-Herraez A, Chohan MO, Villarin JM, Greenwald J, Sun X, Zahran M, Tang A, Lam S, Veenstra-VanderWeele J, Lacefield CO, Bonaventura J, Michaelides M, Chan CS , Yizhar O, Kellendonk C. A non-canonical striatopallidal Go pathway that supports motor control . Nature Communications . 2023;14(1):6712.
McGee JP, Su P , Durbin KR, Hollas MAR, Bateman NW, Maxwell GL, Conrads TP, Fellers RT, Melani RD, Camarillo JM, Kafader JO, Kelleher NL. Automated imaging and identification of proteoforms directly from ovarian cancer tissue . Nature Communications . 2023;14(1):6478.Minneci PC, Bergus KC, Lutz C, Aldrink J, Bence C, Breech L, Dillon PA, Downard C, Ehrlich PF, Fallat M, Fraser JD, Grabowski J, Helmrath M, Hertweck P, Hewitt G, Hirschl RB, Kabre R , Lal DR, Landman M, Leys C, Mak G, Markel T, Pressey J, Raiji M, Rymeski B, Saito J, Sato TT, St Peter SD, Cooper J, Deans K. Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients . JAMA . 2023;330(13):1247-1254.
Necchi A, Faltas BM, Slovin SF, Meeks JJ , Pal SK, Schwartz LH, Huang RSP, Li R, Manley B, Chahoud J, Ross JS, Spiess PE. Immunotherapy in the Treatment of Localized Genitourinary Cancers . JAMA Oncolology . 2023;9(10):1447-1454.
Pang L, Dunterman M, Guo S, Khan F, Liu Y, Taefi E, Bahrami A, Geula C , Hsu WH, Horbinski C, James CD, Chen P. Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma . Nature Immunology . 2023;24(10):1654-1670.Peipert BJ, Potapragada NR , Lantos PM, Harris BS, Reinecke J, Goldman KN. A Geospatial Analysis of Disparities in Access to Oncofertility Services . JAMA Oncology . 2023;9(10):1364-1370.
Ptashkin RN, Ewalt MD, Jayakumaran G, Kiecka I, Bowman AS, Yao J, Casanova J, Lin YD, Petrova-Drus K, Mohanty AS, Bacares R, Benhamida J, Rana S, Razumova A, Vanderbilt C, Balakrishnan Rema A, Rijo I, Son-Garcia J, de Bruijn I, Zhu M, Lachhander S, Wang W, Haque MS, Seshan VE, Wang J, Liu Y, Nafa K, Borsu L, Zhang Y, Aypar U, Suehnholz SP, Chakravarty D, Park JH, Abdel-Wahab O, Mato AR, Xiao W, Roshal M, Yabe M, Batlevi CL, Giralt S, Salles G, Rampal R, Tallman M , Stein EM, Younes A, Levine RL, Perales MA, van den Brink MRM, Dogan A, Ladanyi M, Berger MF, Brannon AR, Benayed R, Zehir A, Arcila ME. Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing . Nature Communications . 2023;14(1):6895.
Serritella AV, Shenoy NK . Nivolumab Plus Ipilimumab vs Nivolumab Alone in Advanced Cancers Other Than Melanoma: A Meta-Analysis . JAMA Oncology . 2023;9(10):1441-1446.Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A, Nejad FK, Mahmoodzadeh A, Sato T, Ramos-Alonso L, Romero AM, Martinez-Pastor MT, Jiang SC, Sah-Teli SK, Li L, Bentrem D, Lopaschuk G, Ben-Sahra I, O'Halloran TV, Shilatifard A, Puig S, Bergelson J, Koivunen P, Ardehali H. Iron drives anabolic metabolism through active histone demethylation and mTORC1 . Nature Cell Biology . 2023;25(10):1478-1494.Smith CS, Álvarez Z, Qiu R, Sasselli IR, Clemons T, Ortega JA , Vilela-Picos M, Wellman H, Kiskinis E, Stupp SI . Enhanced Neuron Growth and Electrical Activity by a Supramolecular Netrin-1 Mimetic Nanofiber . ACS Nano . 2023;17(20):19887-19902.
Tobias DK, Merino J, Ahmad A, et al. (including Lowe Jr WL, Scholtens DM, Fawcett AJ, Josefson JL ). Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine . Nature Medicine . 2023;29(10):2438-2457.
Wong YC, Jayaraj ND, Belton TB, Shum GC, Ball HE, Ren D , Tadenev ALD, Krainc D , Burgess RW, Menichella DM. Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(44):e2313010120.Yap C, Rekowski J, Ursino M, Solovyeva O, Patel D, Dimairo M, Weir CJ, Chan AW, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell KR, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards DP, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, de Bono J. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance . BMJ . 2023;383:e076386.
Yap C, Solovyeva O, de Bono J, Rekowski J, Patel D, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Hopewell S, Ursino M, Rantell KR, Calvert M, Lee S, Kightley A, Ashby D, Chan AW, Garrett-Mayer E, Isaacs JD, Golub R , Kholmanskikh O, Richards D, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, Dimairo M, Weir CJ. Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance . BMJ . 2023;383:e076387.
Youngblood MW, Erson-Omay Z, Li C, Najem H , Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas. Nature Communications . 2023;14(1):6279.
Akula SK, Chen AY, Neil JE, Shao DD, Mo A, Hylton NK, DiTroia S, Ganesh VS, Smith RS , O'Kane K, Yeh RC, Marciano JH, Kirkham S, Kenny CJ, Song JHT, Al Saffar M, Millan F, Harris DJ, Murphy AV, Klemp KC, Braddock SR, Brand H, Wong I, Talkowski ME, O'Donnell-Luria A, Lai A, Hill RS, Mochida GH, Doan RN, Barkovich AJ, Yang E, Amrom D, Andermann E, Poduri A, Walsh CA. Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria . JAMA Neurology . 2023;80(9):980-988.
Borlaug BA, Kitzman DW, Davies MJ, Rasmussen S, Barros E, Butler J, Einfeldt MN, Hovingh GK, Møller DV, Petrie MC, Shah SJ, Verma S, Abhayaratna W, Ahmed FZ, Chopra V, Ezekowitz J, Fu M, Ito H, Lelonek M, Melenovsky V, Núñez J, Perna E, Schou M, Senni M, van der Meer P, Von Lewinski D, Wolf D, Kosiborod MN. Semaglutide in HFpEF across obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial. Nature Medicine . 2023;29(9):2358-2365.
Bouffet E, Hansford JR, Garrè ML, Hara J, Plant-Fox A , Aerts I, Locatelli F, van der Lugt J, Papusha L, Sahm F, Tabori U, Cohen KJ, Packer RJ, Witt O, Sandalic L, Bento Pereira da Silva A, Russo M, Hargrave DR. Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations . New England Journal of Medicine . 2023;389(12):1108-1120.
Burks HE, Pokorny JL, Koetsier JL, Roth-Carter QR, Arnette CR, Gerami P, Seykora JT, Johnson JL, Ren ZY, Green KJ. Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration . Journal of Cell Biology . 2023;222(11).Carlson DA, Hirano I, Gonsalves N, Kahrilas PJ, Araujo IK, Yang M, Tetreault MP, Pandolfino JE. A PhysioMechanical Model of Esophageal Function in Eosinophilic Esophagitis. Gastroenterology . 2023;165(3):552-563.e4.Dale W, Klepin HD, Williams GR, Alibhai SMH, Bergerot C, Brintzenhofeszoc K, Hopkins JO, Jhawer MP, Katheria V, Loh KP, Lowenstein LM, McKoy JM , Noronha V, Phillips T, Rosko AE, Ruegg T, Schiaffino MK, Simmons JF, Jr., Subbiah I, Tew WP, Webb TL, Whitehead M, Somerfield MR, Mohile SG. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy: ASCO Guideline Update . Journal of Clinical Oncology . 2023;41(26):4293.
Dittmar JW, Teplensky MH, Evangelopoulos M, Qin L, Zhang B , Mirkin CA. Tuning DNA Dissociation from Spherical Nucleic Acids for Enhanced Immunostimulation . ACS Nano . 2023;17(18):17996-18007.
Haas KM, McGregor MJ, Bouhaddou M, Polacco BJ, Kim EY , Nguyen TT, Newton BW, Urbanowski M, Kim H , Williams MAP, Rezelj VV, Hardy A, Fossati A, Stevenson EJ, Sukerman E, Kim T, Penugonda S, Moreno E, Braberg H, Zhou Y, Metreveli G, Harjai B, Tummino TA, Melnyk JE, Soucheray M, Batra J, Pache L, Martin-Sancho L, Carlson-Stevermer J, Jureka AS, Basler CF, Shokat KM, Shoichet BK, Shriver LP, Johnson JR, Shaw ML, Chanda SK, Roden DM, Carter TC, Kottyan LC, Chisholm RL, Pacheco JA, Smith ME, Schrodi SJ, Albrecht RA, Vignuzzi M, Zuliani-Alvarez L, Swaney DL, Eckhardt M, Wolinsky SM, White KM, Hultquist JF , Kaake RM, García-Sastre A, Krogan NJ. Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets . Nature Communications . 2023;14(1):6030.
Hofmeyer M, Haas GJ, Jordan E, Cao J, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Wilson Tang WH, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE, Katz S, Pan S, Jimenez J, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Huggins GS, Kinnamon DD, Ni H, Hershberger RE. Rare Variant Genetics and Dilated Cardiomyopathy Severity: The DCM Precision Medicine Study . Circulation . 2023;148(11):872-881.
Intagliata NM, Rahimi RS, Higuera-de-la-Tijera F, Simonetto DA, Farias AQ, Mazo DF, Boike JR, Stine JG, Serper M, Pereira G, Mattos AZ, Marciano S, Davis JPE, Benitez C, Chadha R, Méndez-Sánchez N, deLemos AS, Mohanty A, Dirchwolf M, Fortune BE, Northup PG, Patrie JT, Caldwell SH. Procedural-Related Bleeding in Hospitalized Patients With Liver Disease (PROC-BLeeD): An International, Prospective, Multicenter Observational Study . Gastroenterology . 2023;165(3):717-732.
Jajosky RP, Patel KR, Allen JWL, Zerra PE, Chonat S, Ayona D, Maier CL, Morais D, Wu SC, Luckey CJ, Eisenbarth SC, Roback JD, Fasano RM, Josephson CD, Manis JP, Chai L, Hendrickson JE, Hudson KE, Arthur CM, Stowell SR. Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression . Blood . 2023;142(12):1082-1098.
Jo A, Deniz S, Xu J, Duvoisin RM, DeVries SH, Zhu Y. A sign-inverted receptive field of inhibitory interneurons provides a pathway for ON-OFF interactions in the retina . Nature Communications . 2023;14(1):5937.Kaye KS, Shorr AF, Wunderink RG , Du B, Poirier GE, Rana K, Miller A, Lewis D, O'Donnell J, Chen L, Reinhart H, Srinivasan S, Isaacs R, Altarac D. Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with serious infections caused by Acinetobacter baumannii-calcoaceticus complex: a multicentre, randomised, active-controlled, phase 3, non-inferiority clinical trial (ATTACK). Lancet Infectious Diseases . 2023;23(9):1072-1084.
Kosiborod MN, Abildstrøm SZ, Borlaug BA, Butler J, Rasmussen S, Davies M, Hovingh GK, Kitzman DW, Lindegaard ML, Møller DV, Shah SJ , Treppendahl MB, Verma S, Abhayaratna W, Ahmed FZ, Chopra V, Ezekowitz J, Fu M, Ito H, Lelonek M, Melenovsky V, Merkely B, Núñez J, Perna E, Schou M, Senni M, Sharma K, Van der Meer P, von Lewinski D, Wolf D, Petrie MC. Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity . New England Journal of Medicine . 2023;389(12):1069-1084.
Leech R, Vos De Wael R, Váša F, Xu T, Austin Benn R, Scholz R, Braga RM, Milham MP, Royer J, Bernhardt BC, Jones EJH, Jefferies E, Margulies DS, Smallwood J. Variation in spatial dependencies across the cortical mantle discriminates the functional behaviour of primary and association cortex . Nature Communications . 2023;14(1):5656.
Lu W, Lakonishok M, Gelfand VI. The dynamic duo of microtubule polymerase Mini spindles/XMAP215 and cytoplasmic dynein is essential for maintaining Drosophila oocyte fate . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(39):e2303376120.Madhvapathy SR, Wang JJ , Wang H, Patel M, Chang A, Zheng X , Huang Y, Zhang ZJ, Gallon L, Rogers JA . Implantable bioelectronic systems for early detection of kidney transplant rejectionScience . 2023;381(6662):1105-1112.
Mahadevan KK, McAndrews KM, LeBleu VS , Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA, Ying H, Barekatain Y, Sthanam LK, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. KRAS(G12D) inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8(+) T cells . Cancer Cell . 2023;41(9):1606-1620.e8.
Novakovic MM, Korshunov KS, Grant RA, Martin ME, Valencia HA, Budinger GRS, Radulovic J, Prakriya M. Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels . Nature Communications . 2023;14(1):5500.Pividori M, Lu S, Li B, Su C, Johnson ME, Wei WQ, Feng Q, Namjou B, Kiryluk K, Kullo IJ, Luo Y, Sullivan BD, Voight BF, Skarke C, Ritchie MD, Grant SFA, Greene CS. Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms . Nature Communications . 2023;14(1):5562.
Pratz KW, Cherry M, Altman JK , Cooper BW, Podoltsev NA, Cruz JC, Lin TL, Schiller GJ, Jurcic JG, Asch A, Wu RS, Hill JE, Gill SC, James AJ, Rich ES, Hasabou N, Perl AE, Levis MJ. Gilteritinib in Combination With Induction and Consolidation Chemotherapy and as Maintenance Therapy: A Phase IB Study in Patients With Newly Diagnosed AML . Journal of Clinical Oncology . 2023;41(26):4236.
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zúniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T , Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D. De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8. Nature Communications . 2023;14(1):5660.
Sagar V, Shanahan LK, Zelano CM, Gottfried JA, Kahnt T. High-precision mapping reveals the structure of odor coding in the human brain . Nature Neuroscience . 2023;26(9):1595-1602.Salinas AG, Lee JO, Augustin SM , Zhang S, Patriarchi T, Tian L, Morales M, Mateo Y, Lovinger DM. Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor . Nature Communications . 2023;14(1):5915.
Schaper F, Nordberg J, Cohen AL, Lin C, Hsu J, Horn A, Ferguson MA, Siddiqi SH, Drew W, Soussand L, Winkler AM, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon AJ, Ackermans L, Bubrick EJ, Peters JM, Wu O, Rost NS, Grafman J , Blumenfeld H, Temel Y, Rouhl RPW, Joutsa J, Fox MD. Mapping Lesion-Related Epilepsy to a Human Brain Network . JAMA Neurology . 2023;80(9):891-902.
VanderWalde A, Bellasea SL, Kendra KL, Khushalani NI, Campbell KM, Scumpia PO, Kuklinski LF, Collichio F, Sosman JA , Ikeguchi A, Victor AI, Truong TG, Chmielowski B, Portnoy DC, Chen Y, Margolin K, Bane C, Dasanu CA, Johnson DB, Eroglu Z, Chandra S, Medina E, Gonzalez CR, Baselga-Carretero I, Vega-Crespo A, Garcilazo IP, Sharon E, Hu-Lieskovan S, Patel SP, Grossmann KF, Moon J, Wu MC, Ribas A. Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial. Nature Medicine . 2023;29(9):2278-2285.
Venkatesh KK, Khan SS , Powe CE. Gestational Diabetes and Long-Term Cardiometabolic Health . JAMA . 2023;330(9):870-871.
Wang Y, Li Q, Tao B, Angelini M, Ramadoss S, Sun B, Wang P, Krokhaleva Y, Ma F , Gu Y, Espinoza A, Yamauchi K, Pellegrini M, Novitch B, Olcese R, Qu Z, Song Z, Deb A. Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis. Science . 2023;381(6665):1480-1487.
Fantus RJ, Brannigan RE , Davis AM. Diagnosis and Management of Priapism . JAMA . 2023;330(6):559-560.
Foltman M, Mendez I, Bech-Serra JJ, de la Torre C, Brace JL, Weiss EL , Lucas M, Queralt E, Sanchez-Diaz A. TOR complex 1 negatively regulates NDR kinase Cbk1 to control cell separation in budding yeast . PLoS Biology . 2023;21(8):e3002263.
Giladi N, Alcalay RN, Cutter G, Gasser T, Gurevich T, Hoeglinger GU, Marek K, Pacchetti C, Schapira AHV, Scherzer CR, Simuni T , Minini P, Sardi SP, Peterschmitt MJ. Safety and efficacy of venglustat in GBA1-associated Parkinson's disease: an international, multicentre, double-blind, randomised, placebo-controlled, phase 2 trial . Lancet Neurology . 2023;22(8):661-671.
Goyal Y , Busch GT, Pillai M , Li JX, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J , Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS , Li HY, Chen YQ, Chai CD , Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A. Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells . Nature . 2023;620(7974):651.Gritsina G, Fong KW, Lu XD, Lin ZY, Xie WQ, Agarwal S, Lin D, Schiltz GE , Beltran H, Corey E, Morrissey C, Wang YZ, Zhao JC, Hussain M, Yu JD . Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth . Journal of Clinical Investigation . 2023;133(15).Han S, Lee M, Shin Y, Giovanni R, Chakrabarty RP, Herrerias MM, Dada LA, Flozak AS, Reyfman PA, Khuder B, Reczek CR , Gao L, Lopéz-Barneo J, Gottardi CJ, Budinger GRS, Chandel NS . Mitochondrial integrated stress response controls lung epithelial cell fate . Nature . 2023;620(7975):890-897.Huang X, Zhang X, Machireddy N, Evans CE, Trewartha SD , Hu G, Fang Y, Mutlu GM, Wu D, Zhao YY. Endothelial FoxM1 reactivates aging-impaired endothelial regeneration for vascular repair and resolution of inflammatory lung injury . Science Translational Medicine . 2023;15(709):eabm5755.Jain S, Pei LM, Spraggins JM, et al (including: Kelleher NL, Arvantitis C, Caldwell M, Henning N, Su P, Scholten D, Wei JJ, Weimer A ). Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP). Nature Cell Biology . 2023;25(8):1089-1100.
Jordan E, Kinnamon DD, Haas GJ, Hofmeyer M, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Tang WHW, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE , Katz S, Pan S, Jimenez J, Fishbein DP, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Mead JO, Hurst N, Cao J, Huggins GS, Cowan J, Ni H, Rehm HL, Jarvik GP, Vatta M, Burke W, Hershberger RE. Genetic Architecture of Dilated Cardiomyopathy in Individuals of African and European Ancestry . JAMA . 2023;330(5):432-441.
Kalinsky K, Accordino MK, Chiuzan C, Mundi PS, Sakach E, Sathe C, Ahn H, Trivedi MS, Novik Y, Tiersten A, Raptis G, Baer LN, Oh SY, Zelnak AB, Wisinski KB, Andreopoulou E, Gradishar WJ , Stringer-Reasor E, Reid SA, O'Dea A, O'Regan R, Crew KD, Hershman DL. Randomized Phase II Trial of Endocrine Therapy With or Without Ribociclib After Progression on Cyclin-Dependent Kinase 4/6 Inhibition in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer: MAINTAIN Trial. Journal of Clinical Oncology . 2023;41(24):4004-4013.
Kittleson MM, Sharma K, Brennan DC, Cheng XS, Chow SL, Colvin M, DeVore AD, Dunlay SM, Fraser M, Garonzik-Wang J, Khazanie P, Korenblat KM, Pham DT . Dual-Organ Transplantation: Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation: A Scientific Statement From the American Heart Association . Circulation . 2023;148(7):622-636.
Kondev V, Najeed M, Loomba N, Brown J, Winder DG, Grueter BA, Patel S. Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(34):e2300585120.
Kondo T, Dewan P, Anand IS, Desai AS, Packer M, Zile MR, Pfeffer MA, Solomon SD, Abraham WT, Shah SJ , Lam CSP, Jhund PS, McMurray JJV. Clinical Characteristics and Outcomes in Patients With Heart Failure: Are There Thresholds and Inflection Points in Left Ventricular Ejection Fraction and Thresholds Justifying a Clinical Classification? Circulation . 2023;148(9):732-749.
Mann JR, McKenna ED, Mawrie D, Papakis V, Alessandrini F, Anderson EN, Mayers R, Ball HE, Kaspi E, Lubinski K, Baron DM, Tellez L, Landers JE, Pandey UB, Kiskinis E . Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import . Science Advances . 2023;9(33):eadi5548.McLaren PJ, Porreca I, Iaconis G, et al. (including Kim EY, Walter M, Simons LM, Nam K, Hultquist JF, Wolinsky SM ). Africa-specific human genetic variation near CHD1L associates with HIV-1 load . Nature . 2023;620(7976):1025-1030.
Meador KJ, Cohen MJ, Loring DW, Matthews AG, Brown C, Robalino CP, Birnbaum AK, Voinescu PE, Kalayjian LA, Gerard EE, Gedzelman ER, Hanna J, Cavitt J, Sam M, French JA, Hwang S, Pack AM, Pennell PB, Grp MI. Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study . Lancet Neurology . 2023;22(8):712-722.
Moritz L, Schon SB, Rabbani M, Sheng Y, Agrawal R, Glass-Klaiber J, Sultan C, Camarillo JM, Clements J, Baldwin MR, Diehl AG, Boyle AP, O'Brien PJ, Ragunathan K, Hu YC, Kelleher NL, Nandakumar J, Li JZ, Orwig KE, Redding S, Hammoud SS. Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1. Nature Structural & Molecular Biology . 2023;30(8):1077.
Opal P. Spinocerebellar ataxia type 1: It's not just about Purkinje cells. Neuron . 2023;111(16):2461-2462.Qi R, Sammler E, Gonzalez-Hunt CP, Barraza I, Pena N, Rouanet JP, Naaldijk Y, Goodson S, Fuzzati M, Blandini F, Erickson KI, Weinstein AM, Lutz MW, Kwok JB, Halliday GM, Dzamko N, Padmanabhan S, Alcalay RN, Waters C, Hogarth P, Simuni T , Smith D, Marras C, Tonelli F, Alessi DR, West AB, Shiva S, Hilfiker S, Sanders LH. A blood-based marker of mitochondrial DNA damage in Parkinson's disease. Science Translational Medicine . 2023;15(711):eabo1557.
Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA , Vlachos IS, Muller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL , Börner K, Radtke AJ. Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging . Nature Methods . 2023;20(8):1174-1178.
Rahi A, Chakraborty M, Agarwal S, Vosberg KM, Agarwal S, Wang AY, McKenney RJ, Varma D. The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore-microtubule coupling unit . Journal of Cell Biology . 2023;222(8)Ren XS, Manzanares LD, Piccolo EB, Urbanczyk JM, Sullivan DP, Yalom LK, Bui TM, Lantz C, Najem H, Dulai PS, Heimberger AB, Thorp EB, Sumagin R. Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa . Journal of Clinical Investigation . 2023;133(15).Siddiqi T, Maloney DG, Kenderian SS, Brander DM, Dorritie K, Soumerai J, Riedell PA, Shah NN, Nath R, Fakhri B, Stephens DM, Ma S , Feldman T, Solomon SR, Schuster SJ, Perna SK, Tuazon SA, Ou SS, Papp E, Peiser L, Chen Y, Wierda WG. Lisocabtagene maraleucel in chronic lymphocytic leukaemia and small lymphocytic lymphoma (TRANSCEND CLL 004): a multicentre, open-label, single-arm, phase 1-2 study . Lancet . 2023;402(10402):641-654.
Stamm B, Royan R, Giurcanu M, Messe SR, Jauch EC, Prabhakaran S. Door-in-Door-out Times for Interhospital Transfer of Patients With Stroke . JAMA . 2023;330(7):636-649.Suresh RV, Dunnam C, Vaidya D, Wood RA, Bochner BS, MacGlashan DW, Jr., Dispenza MC. A phase II study of Bruton's tyrosine kinase inhibition for the prevention of anaphylaxis. Journal of Clinical Investigation . 2023;133(16).
Talyzina A, Han Y, Banerjee C, Fishbain S, Reyes A, Vafabakhsh R, He Y . Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation . Molecular Cell . 2023;83(15):2641-2652.e7.
Templeton CW, Laimins LA. p53-dependent R-loop formation and HPV pathogenesis . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(35):e2305907120.Tsuboyama K, Dauparas J, Chen J, Laine E, Mohseni Behbahani Y, Weinstein JJ, Mangan NM, Ovchinnikov S, Rocklin GJ . Mega-scale experimental analysis of protein folding stability in biology and design . Nature . 2023;620(7973):434-444.
van de Vegte Y, Eppinga RN, van der Ende MY, et al. (including Cornelis MD ). Genetic insights into resting heart rate and its role in cardiovascular disease . Nature Communications . 2023;14(1).
Varberg KM, Dominguez EM, Koseva B, Varberg JM, McNally RP, Moreno-Irusta A, Wesley ER, Iqbal K, Cheung WA, Schwendinger-Schreck C, Smail C, Okae H, Arima T, Lydic M, Holoch K, Marsh C, Soares MJ, Grundberg E. Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape . Nature Communications . 2023;14(1).
Wang ML, Jurczak W, Zinzani PL, Eyre TA, Cheah CY, Ujjani CS, Koh Y, Izutsu K, Gerson JN, Flinn I, Tessoulin B, Alencar AJ, Ma S , Lewis D, Lech-Maranda E, Rhodes J, Patel K, Maddocks K, Lamanna N, Wang Y, Tam CS, Munir T, Nagai H, Hernandez-Ilizaliturri F, Kumar A, Fenske TS, Seymour JF, Zelenetz AD, Nair B, Tsai DE, Balbas M, Walgren RA, Abada P, Wang C, Zhao J, Mato AR, Shah NN. Pirtobrutinib in Covalent Bruton Tyrosine Kinase Inhibitor Pretreated Mantle-Cell Lymphoma . Journal of Clinical Oncology . 2023;41(24):3988-3997.
Watson K, Oberman M. Abortion Counseling, Liability, and the First Amendment . New England Journal of Medicine . 2023;389(7):663-667.Xia JY, Hepler C, Tran P, Waldeck NJ, Bass J, Prindle A . Engineered calprotectin-sensing probiotics for IBD surveillance in humans . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(32):e2221121120.Yang Y, Li C, Palmer LC, Stupp SI . Autonomous hydrogel locomotion regulated by light and electric fields . Science Advances . 2023;9(31).
Yoo SGK, Chung GS, Bahendeka SK, Sibai AM, Damasceno A, Farzadfar F, Rohloff P, Houehanou C, Norov B, Karki KB, Azangou-Khyavy M, Marcus ME, Aryal KK, Brant LCC, Theilmann M, Cífková R, Lunet N, Gurung MS, Mwangi JK, Martins J, Haghshenas R, Sturua L, Vollmer S, Bärnighausen T, Atun R, Sussman JB, Singh K, Saeedi Moghaddam S, Guwatudde D, Geldsetzer P, Manne-Goehler J, Huffman MD , Davies JI, Flood D. Aspirin for Secondary Prevention of Cardiovascular Disease in 51 Low-, Middle-, and High-Income Countries . JAMA . 2023;330(8):715-724.
Yun S, Yang B, Anair JD, Martin MM, Fleps SW, Pamukcu A, Yeh NH, Contractor A, Kennedy A, Parker JG. Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons . Nature Neuroscience . 2023;26(8):1417-1428.Zheng B, Gold S, Iwanaszko M, Howard BC, Wang L, Shilatifard A. Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation . Molecular Cell . 2023;83(16):2896-2910.e4.
Brastianos PK, Twohy E, Geyer S, Gerstner ER, Kaufmann TJ, Tabrizi S, Kabat B, Thierauf J, Ruff MW, Bota DA, Reardon DA, Cohen AL, De La Fuente MI, Lesser GJ, Campian J, Agarwalla PK, Kumthekar P , Mann B, Vora S, Knopp M, Iafrate AJ, Curry WT, Jr., Cahill DP, Shih HA, Brown PD, Santagata S, Barker FG, 2nd, Galanis E. BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas . New England Journal of Medicine . 2023;389(2):118-126.
Buyukcelebi K, Chen X, Abdula F, Elkafas H, Duval AJ, Ozturk H, Seker-Polat F, Jin Q, Yin P, Feng Y, Bulun SE, Wei JJ, Yue F, Adli M. Engineered MED12 mutations drive leiomyoma-like transcriptional and metabolic programs by altering the 3D genome compartmentalization . Nature Communications . 2023;14(1):4057.Cameron NA, Yee LM, Dolan BM, O'Brien MJ, Greenland P, Khan SS . Trends in Cardiovascular Health Counseling Among Postpartum Individuals . JAMA . 2023;330(4):359-367.Chen Z, Lin Z, Obaid SN, Rytkin E, George SA, Bach C, Madrid M, Liu M, LaPiano J, Fehr A, Shi X, Quirion N, Russo B, Knight H, Aduwari A, Efimov IR , Lu L. Soft, bioresorbable, transparent microelectrode arrays for multimodal spatiotemporal mapping and modulation of cardiac physiology . Science Advances . 2023;9(27):eadi0757.
Coombes RC, Howell S, Lord SR, Kenny L, Mansi J, Mitri Z, Palmieri C, Chap LI, Richards P, Gradishar W , Sardesai S, Melear J, O'Shaughnessy J, Ward P, Chalasani P, Arkenau T, Baird RD, Jeselsohn R, Ali S, Clack G, Bahl A, McIntosh S, Krebs MG. Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib . Nature Communications . 2023;14(1):4444.
Courbon G, Thomas JJ, Martinez-Calle M, Wang X, Spindler J, Von Drasek J, Hunt-Tobey B, Mehta R, Isakova T, Chang W, Creemers JWM, Ji P, Martin A, David V. Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation . Blood . 2023;142(1):106-118.Courtney CD, Pamukcu A, Chan CS . Cell and circuit complexity of the external globus pallidus . Nature Neuroscience . 2023;26(7):1147-1159.Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson AB, 3rd . Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200 . Journal of Clinical Oncology . 2023;41(21):3670-3675.
Gu F, Boisjoli M, Naghavi MH . HIV-1 promotes ubiquitination of the amyloidogenic C-terminal fragment of APP to support viral replication . Nature Communications . 2023;14(1):4227.Gupta K, Spertus JA, Birmingham M, Gosch KL, Husain M, Kitzman DW, Pitt B, Shah SJ , Januzzi JL, Lingvay I, Butler J, Kosiborod M, Lanfear DE. Racial Differences in Quality of Life in Patients With Heart Failure Treated With Sodium-Glucose Cotransporter 2 Inhibitors: A Patient-Level Meta-Analysis of the CHIEF-HF, DEFINE-HF, and PRESERVED-HF Trials . Circulation . 2023;148(3):220-228.
Hoffman MK, Clifton RG, Biggio JR, Saade GR, Ugwu LG, Longo M, Bousleiman SZ, Clark K, Grobman WA, Frey HA, Chauhan SP, Dugoff L, Manuck TA, Chien EK, Rouse DJ, Simhan HN, Esplin MS, Macones GA. Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix: The TOPS Randomized Clinical Trial . JAMA . 2023;330(4):340-348.
Hunt AC, Vögeli B, Hassan AO, Guerrero L, Kightlinger W, Yoesep DJ, Krüger A, DeWinter M , Diamond MS, Karim AS, Jewett MC . A rapid cell-free expression and screening platform for antibody discovery . Nature Communications . 2023;14(1):3897.
Hussain M , Tombal B, Saad F, Fizazi K, Sternberg CN, Crawford ED, Shore N, Kopyltsov E, Kalebasty AR, Bögemann M, Ye D, Cruz F, Suzuki H, Kapur S, Srinivasan S, Verholen F, Kuss I, Joensuu H, Smith MR. Darolutamide Plus Androgen-Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer by Disease Volume and Risk Subgroups in the Phase III ARASENS Trial . Journal of Clinical Oncology . 2023;41(20):3595-3607.Jovisic M, Mambetsariev N, Singer BD , Morales-Nebreda L. Differential roles of regulatory T cells in acute respiratory infections . Journal of Clinical Investigation . 2023;133(14).
Kappelman MD, Wohl DA, Herfarth HH, Firestine AM, Adler J, Ammoury RF, Aronow JE, Bass DM, Bass JA, Benkov K, Tobi CB, Boccieri ME, Boyle BM, Brinkman WB, Cabera JM, Chun K, Colletti RB, Dodds CM, Dorsey JM, Ebach DR, Entrena E, Forrest CB, Galanko JA, Grunow JE, Gulati AS, Ivanova A, Jester TW, Kaplan JL, Kugathasan S, Kusek ME, Leibowitz IH, Linville TM, Lipstein EA, Margolis PA, Minar P, Molle-Rios Z, Moses J, Olano KK, Osaba L, Palomo PJ, Pappa H, Park KT, Pashankar DS, Pitch L, Robinson M, Samson CM, Sandberg KC, Schuchard JR, Seid M, Shelly KA, Steiner SJ, Strople JA, Sullivan JS, Tung J, Wali P, Zikry M, Weinberger M, Saeed SA, Bousvaros A. Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial . Gastroenterology . 2023;165(1):149-161.e7.
Lagu T, Schroth SL, Haywood C, Heinemann A, Kessler A, Morse L, Khan SS, Kershaw KN, Nash MS. Diagnosis and Management of Cardiovascular Risk in Individuals With Spinal Cord Injury: A Narrative Review. Circulation . 2023;148(3):268-277.Lin S, Cienfuegos S, Ezpeleta M, Gabel K, Pavlou V, Mulas A, Chakos K, McStay M, Wu J, Tussing-Humphreys L, Alexandria SJ , Sanchez J, Unterman T, Varady KA. Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population : A Randomized Controlled Trial . Annals of Internal Medicine . 2023;176(7):885-895.
Mato AR, Woyach JA, Brown JR, Ghia P, Patel K, Eyre TA, Munir T, Lech-Maranda E, Lamanna N, Tam CS, Shah NN, Coombs CC, Ujjani CS, Fakhri B, Cheah CY, Patel MR, Alencar AJ, Cohen JB, Gerson JN, Flinn IW, Ma S , Jagadeesh D, Rhodes JM, Hernandez-Ilizaliturri F, Zinzani PL, Seymour JF, Balbas M, Nair B, Abada P, Wang C, Ruppert AS, Wang D, Tsai DE, Wierda WG, Jurczak W. Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia . New England Journal of Medicine . 2023;389(1):33-44.
Mentias A, Mujahid MS, Sumarsono A, Nelson RK, Madron JM, Powell-Wiley TM, Essien UR, Keshvani N, Girotra S, Morris AA, Sims M, Capers Qt, Yancy C , Desai MY, Menon V, Rao S, Pandey A. Historical Redlining, Socioeconomic Distress, and Risk of Heart Failure Among Medicare Beneficiaries . Circulation . 2023;148(3):210-219.
Mihaylova MM, Chaix A, Delibegovic M, Ramsey JJ, Bass J , Melkani G, Singh R, Chen Z, Ja WW, Shirasu-Hiza M, Latimer MN, Mattison JA, Thalacker-Mercer AE, Dixit VD, Panda S, Lamming DW. When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging. Cell Metabolism . 2023;35(7):1114-1131.
Osho A, Fernandes MF, Poudel R, de Lemos J, Hong H, Zhao J, Li S, Thomas K, Kikuchi DS, Zegre-Hemsey J, Ibrahim N, Shah NS , Hollowell L, Tamis-Holland J, Granger CB, Cohen M, Henry T, Jacobs AK, Jollis JG, Yancy CW, Goyal A. Race-Based Differences in ST-Segment-Elevation Myocardial Infarction Process Metrics and Mortality From 2015 Through 2021: An Analysis of 178 062 Patients From the American Heart Association Get With The Guidelines-Coronary Artery Disease Registry . Circulation . 2023;148(3):229-240.
Patel AP, Wang M, Ruan Y, Koyama S, Clarke SL, Yang X, Tcheandjieu C, Agrawal S , Fahed AC, Ellinor PT, Tsao PS, Sun YV, Cho K, Wilson PWF, Assimes TL, van Heel DA, Butterworth AS, Aragam KG, Natarajan P, Khera AV. A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease . Nature Medicine . 2023;29(7):1793-1803.
Peng W, Schröder LF, Song P, Wong YC, Krainc D. Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease . Science Advances . 2023;9(29):eadh3347.Pyrros A, Borstelmann SM, Mantravadi R, Zaiman Z, Thomas K, Price B, Greenstein E, Siddiqui N, Willis M, Shulhan I, Hines-Shah J, Horowitz JM, Nikolaidis P, Lungren MP, Rodríguez-Fernández JM, Gichoya JW, Koyejo S, Flanders AE, Khandwala N, Gupta A, Garrett JW, Cohen JP, Layden BT, Pickhardt PJ, Galanter W. Opportunistic detection of type 2 diabetes using deep learning from frontal chest radiographs . Nature Communications . 2023;14(1):4039.
Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Muller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL , Börner K, Radtke AJ. Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging . Nature Methods . 2023;20(8):1174-1178.
Shi T, Burg AR, Caldwell JT, Roskin KM, Castro-Rojas CM, Chukwuma PC, Gray GI, Foote SG, Alonso JA, Cuda CM , Allman DA, Rush JS, Regnier CH, Wieczorek G, Alloway RR, Shields AR, Baker BM, Woodle ES, Hildeman DA. Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality . Journal of Clinical Investigation . 2023;133(14).
Shiau CK, Lu L, Kieser R, Fukumura K, Pan T, Lin HY , Yang J, Tong EL, Lee G, Yan Y , Huse JT, Gao R. High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors . Nature Communications . 2023;14(1):4124.Soni A, Herbert C, Lin H, Yan Y, Pretz C, Stamegna P, Wang B, Orwig T, Wright C, Tarrant S, Behar S, Suvarna T, Schrader S, Harman E, Nowak C, Kheterpal V, Rao LV, Cashman L, Orvek E, Ayturk D, Gibson L, Zai A, Wong S, Lazar P, Wang Z, Filippaios A, Barton B, Achenbach CJ, Murphy RL, Robinson ML, Manabe YC, Pandey S, Colubri A, O'Connor L, Lemon SC, Fahey N, Luzuriaga KL, Hafer N, Roth K, Lowe T, Stenzel T, Heetderks W, Broach J, McManus DD. Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection : A Prospective Cohort Study . Annals of Internal Medicine . 2023;176(7):975-982.
Takata N, Miska JM, Morgan MA, Patel P, Billingham LK, Joshi N, Schipma MJ, Dumar ZJ, Joshi NR, Misharin AV, Embry RB, Fiore L, Gao P, Diebold LP, McElroy GS, Shilatifard A, Chandel NS, Oliver G . Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis . Nature Communications . 2023;14(1):4129.Thakar MS, Logan BR, Puck JM, Dunn EA, Buckley RH, Cowan MJ, O'Reilly RJ, Kapoor N, Satter LF, Pai SY, Heimall J, Chandra S, Ebens CL, Chellapandian D, Williams O, Burroughs LM, Saldana BD, Rayes A, Madden LM, Chandrakasan S, Bednarski JJ, 2nd, DeSantes KB, Cuvelier GDE, Teira P, Gillio AP, Eissa H, Knutsen AP, Goldman FD, Aquino VM, Shereck EB, Moore TB, Caywood EH, Lugt MTV, Rozmus J, Broglie L, Yu LC, Shah AJ, Andolina JR, Liu X, Parrott RE, Dara J, Prockop S, Martinez CA, Kapadia M, Jyonouchi SC, Sullivan KE, Bleesing JJ, Chaudhury S, Petrovic A, Keller MD, Quigg TC, Parikh S, Shenoy S, Seroogy C, Rubin T, Decaluwe H, Routes JM, Torgerson TR, Leiding JW, Pulsipher MA, Kohn DB, Griffith LM, Haddad E, Dvorak CC, Notarangelo LD. Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium . Lancet . 2023;402(10396):129-140.
Wang D, Li H, Chandel NS, Dou Y, Yi R . MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters . Nature Communications . 2023;14(1):4404.Zhao Z, Cao K, Watanabe J, Philips CN, Zeidner JM, Ishi Y, Wang Q, Gold SR, Junkins K, Bartom ET, Yue F, Chandel NS, Hashizume R, Ben-Sahra I, Shilatifard A . Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations . Journal of Clinical Investigation . 2023;133(13)
Chang DR, Wang ZJ, Flynn CD, Mahmud A, Labib M, Wang HS, Geraili A, Li XL, Zhang JQ, Sargent EH, Kelley SO . A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities . Nature Chemistry . 2023;15(6):773.
Chen S, Vogt A, Lee L, Naila T, McKeown R, Tomkinson AE, Lees-Miller SP, He Y. Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ . Science Advances . 2023;9(22):eadg2838.
Drumm MR, Wang W, Sears TK, Bell-Burdett K , Javier R, Cotton KY, Webb B, Byrne K , Unruh D, Thirunavu V, Walshon J, Steffens A, McCortney K, Lukas RV, Phillips JJ, Mohamed E, Finan JD, Santana-Santos L, Heimberger AB , Franz CK, Kurz J, Templer JW , Swanson GT, Horbinski C. Postoperative risk of IDH-mutant glioma-associated seizures and their potential management with IDH-mutant inhibitors . Journal of Clinical Investigation . 2023;133(12).
Eskander RN, Sill MW, Beffa L, Moore RG, Hope JM, Musa FB, Mannel R, Shahin MS, Cantuaria GH, Girda E, Mathews C, Kavecansky J, Leath CA, 3rd, Gien LT, Hinchcliff EM , Lele SB, Landrum LM, Backes F, O'Cearbhaill RE, Al Baghdadi T, Hill EK, Thaker PH, John VS, Welch S, Fader AN, Powell MA, Aghajanian C. Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer . New England Journal of Medicine . 2023;388(23):2159-2170.
Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM, Rasmussen L, Schneider D, Starren J, Donnelly HK, Donayre A, Luo Y, Budinger GRS, Wunderink RG, Misharin AV, Singer BD . Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19 . Journal of Clinical Investigation . 2023;133(12).Grabner CP, Futagi D, Shi J , Bindokas V, Kitano K, Schwartz EA, DeVries SH . Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse . Nature Communications . 2023;14(1):3486.
Kim K, Joyce BT, Nannini DR, Zheng Y , Gordon-Larsen P, Shikany JM, Lloyd-Jones DM , Hu M, Nieuwenhuijsen MJ, Vaughan DE, Zhang K, Hou L. Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status. Science Advances . 2023;9(26):eadf8140.Korpanty J, Wang C, Gianneschi NC . Upper critical solution temperature polymer assemblies via variable temperature liquid phase transmission electron microscopy and liquid resonant soft X-ray scattering . Nature Communications . 2023;14(1):3441.
Kurniansyah N, Goodman MO, Khan AT, Wang J, Feofanova E, Bis JC, Wiggins KL, Huffman JE, Kelly T, Elfassy T, Guo X, Palmas W, Lin HJ, Hwang SJ, Gao Y, Young K, Kinney GL, Smith JA, Yu B, Liu S, Wassertheil-Smoller S, Manson JE, Zhu X, Chen YI, Lee IT, Gu CC, Lloyd-Jones DM , Zöllner S, Fornage M, Kooperberg C, Correa A, Psaty BM, Arnett DK, Isasi CR, Rich SS, Kaplan RC, Redline S, Mitchell BD, Franceschini N, Levy D, Rotter JI, Morrison AC, Sofer T. Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups . Nature Communications . 2023;14(1):3202.
Lu L, Wang JR, Henderson YC, Bai S, Yang J, Hu M, Shiau CK , Pan T, Yan Y , Tran TM, Li J, Kieser R, Zhao X, Wang J, Nurieva R, Williams MD, Cabanillas ME, Dadu R, Busaidy NL, Zafereo M, Navin N, Lai SY, Gao R. Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics . Journal of Clinical Investigation . 2023;133(11).
Martinez-Calle M, Courbon G, Hunt-Tobey B, Francis C, Spindler J, Wang X, Dos Reis LM, Martins CS, Salusky IB, Malluche H, Nickolas TL, Moyses RM, Martin A, David V . Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy . Journal of Clinical Investigation . 2023;133(11).Nassiri F, Patil V, Yefet LS, Singh O, Liu J, Dang RMA, Yamaguchi TN, Daras M, Cloughesy TF, Colman H, Kumthekar PU , Chen CC, Aiken R, Groves MD, Ong SS, Ramakrishna R, Vogelbaum MA, Khagi S, Kaley T, Melear JM, Peereboom DM, Rodriguez A, Yankelevich M, Nair SG, Puduvalli VK, Aldape K, Gao A, López-Janeiro Á, de Andrea CE, Alonso MM, Boutros P, Robbins J, Mason WP, Sonabend AM, Stupp R , Fueyo J, Gomez-Manzano C, Lang FF, Zadeh G. Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nature Medicine . 2023;29(6):1370-1378.
Rahi A, Chakraborty M, Agarwal S, Vosberg KM, Agarwal S, Wang AY, McKenney RJ, Varma D. The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore-microtubule coupling unit . Journal of Cell Biology . 2023;222(8):31.Schroder JN, Patel CB, DeVore AD, Bryner BS, Casalinova S, Shah A, Smith JW, Fiedler AG, Daneshmand M, Silvestry S, Geirsson A, Pretorius V, Joyce DL, Um JY, Esmailian F, Takeda K, Mudy K, Shudo Y, Salerno CT, Pham SM, Goldstein DJ, Philpott J, Dunning J, Lozonschi L, Couper GS, Mallidi HR, Givertz MM, Pham DT , Shaffer AW, Kai M, Quader MA, Absi T, Attia TS, Shukrallah B, Sun BC, Farr M, Mehra MR, Madsen JC, Milano CA, D'Alessandro DA. Transplantation Outcomes with Donor Hearts after Circulatory Death . New England Journal of Medicine . 2023;388(23):2121-2131.
Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, Bécavin C, Berg M, Chichelnitskiy E, Chung MI, Collin A, Gay ACA, Gote-Schniering J, Hooshiar Kashani B, Inecik K, Jain M , Kapellos TS, Kole TM, Leroy S, Mayr CH, Oliver AJ, von Papen M, Peter L, Taylor CJ, Walzthoeni T, Xu C, Bui LT, De Donno C, Dony L, Faiz A, Guo M, Gutierrez AJ, Heumos L, Huang N, Ibarra IL, Jackson ND, Kadur Lakshminarasimha Murthy P, Lotfollahi M, Tabib T, Talavera-López C, Travaglini KJ, Wilbrey-Clark A, Worlock KB, Yoshida M, van den Berge M, Bossé Y, Desai TJ, Eickelberg O, Kaminski N, Krasnow MA, Lafyatis R, Nikolic MZ, Powell JE, Rajagopal J, Rojas M, Rozenblatt-Rosen O, Seibold MA, Sheppard D, Shepherd DP, Sin DD, Timens W, Tsankov AM, Whitsett J, Xu Y, Banovich NE, Barbry P, Duong TE, Falk CS, Meyer KB, Kropski JA, Pe'er D, Schiller HB, Tata PR, Schultze JL, Teichmann SA, Misharin AV , Nawijn MC, Luecken MD, Theis FJ. An integrated cell atlas of the lung in health and disease . Nature Medicine . 2023;29(6):1563-1577.
Thaweethai T, Jolley SE, Karlson EW, et al. (including Lee LM ). Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection . JAMA . 2023;329(22):1934-1946.
Yu Z, Peng Y, Gao J, Zhou M, Shi L, Zhao F, Wang C, Tian X, Feng L, Huo X, Zhang B, Liu M, Fang D , Ma X. The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis . Science Advances . 2023;9(26):eade0387.
Berg WA, Zuley ML, Chang TS, Gizienski TA, Chough DM, Böhm-Vélez M, Sharek DE, Straka MR, Hakim CM, Hartman JY, Harnist KS, Tyma CS, Kelly AE, Waheed U, Houshmand G , Nair BE, Shinde DD, Lu AH, Bandos AI, Berg JM, Lettiere NB, Ganott MA. Prospective Multicenter Diagnostic Performance of Technologist-Performed Screening Breast Ultrasound After Tomosynthesis in Women With Dense Breasts (the DBTUST ). Journal of Clinical Oncology . 2023;41(13):2403-2415.
Bryan LJ, Casulo C, Allen PB, Smith SE, Savas H, Dillehay GL, Karmali R, Pro B, Kane KL, Bazzi LA, Chmiel JS, Palmer BA, Mehta J, Gordon LI, Winter JN . Pembrolizumab Added to Ifosfamide, Carboplatin, and Etoposide Chemotherapy for Relapsed or Refractory Classic Hodgkin Lymphoma: A Multi-institutional Phase 2 Investigator-Initiated Nonrandomized Clinical Trial . JAMA Oncology . 2023;9(5):683-691.
Caraballo C, Massey DS, Ndumele CD, Haywood T, Kaleem S, King T, Liu Y, Lu Y, Nunez-Smith M, Taylor HA, Watson KE, Herrin J, Yancy CW , Faust JS, Krumholz HM. Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020 . JAMA . 2023;329(19):1662-1670.
D'Angelica MI, Ellis RJ, Liu JB, Brajcich BC, Gönen M, Thompson VM, Cohen ME, Seo SK, Zabor EC, Babicky ML, Bentrem DJ , Behrman SW, Bertens KA, Celinski SA, Chan CHF, Dillhoff M, Dixon MEB, Fernandez-Del Castillo C, Gholami S, House MG, Karanicolas PJ, Lavu H, Maithel SK, McAuliffe JC, Ott MJ, Reames BN, Sanford DE, Sarpel U, Scaife CL, Serrano PE, Smith T, Snyder RA, Talamonti MS, Weber SM, Yopp AC, Pitt HA, Ko CY. Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy: A Randomized Clinical Trial. JAMA . 2023;329(18):1579-1588.
Greenhawt M, Sindher SB, Wang J, O'Sullivan M, du Toit G, Kim EH, Albright D, Anvari S, Arends N, Arkwright PD, Bégin P, Blumchen K, Bourrier T, Brown-Whitehorn T, Cassell H, Chan ES, Ciaccio CE, Deschildre A, Divaret-Chauveau A, Dorris SL, Dorsey MJ, Eiwegger T, Erlewyn-Lajeunesse M, Fleischer DM, Ford LS, Garcia-Lloret M, Giovannini-Chami L, Hourihane JO, Jay N, Jones SM, Kerns LA, Kloepfer KM, Leonard S, Lezmi G, Lieberman JA, Lomas J, Makhija M , Parrish C, Peake J, Perrett KP, Petroni D, Pfützner W, Pongracic JA, Quinn P, Robison RG, Sanders G, Schneider L, Sharma HP, Trujillo J, Turner PJ, Tuttle K, Upton JE, Varshney P, Vickery BP, Vogelberg C, Wainstein B, Wood RA, Bee KJ, Campbell DE, Green TD, Rouissi R, Peillon A, Bahnson HT, Bois T, Sampson HA, Burks AW. Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy . New England Journal of Medicine . 2023;388(19):1755-1766.
Heil CM, Patil A, Vanthournout B, Singla S, Bleuel M, Song JJ, Hu Z, Gianneschi NC , Shawkey MD, Sinha SK, Jayaraman A, Dhinojwala A. Mechanism of structural colors in binary mixtures of nanoparticle-based supraballs . Science Advances . 2023;9(21):eadf2859.
Hunter PJ, Awoyemi T , Ayede AI, Chico RM, David AL, Dewey KG, Duggan CP, Gravett M, Prendergast AJ, Ramakrishnan U, Ashorn P, Klein N. Biological and pathological mechanisms leading to the birth of a small vulnerable newborn . Lancet . 2023;401(10389):1720-1732.
Icho S, Ward JS, Tam J, Kociolek LK , Theriot CM, Melnyk RA. Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(19):e2301252120.
Jajosky R, Patel SR, Wu SC, Patel K, Covington M, Vallecillo-Zúniga M, Ayona D, Bennett A, Luckey CJ, Hudson KE, Hendrickson JE, Eisenbarth SC , Josephson CD, Zerra PE, Stowell SR, Arthur CM. Prior immunization against an intracellular antigen enhances subsequent red blood cell alloimmunization in mice . Blood . 2023;141(21):2642-2653.
Jang G, Contreras Castillo S, Esteva E, Upadhaya S, Feng J, Adams NM, Richard E, Awatramani R, Sawai CM, Reizis B. Stem cell decoupling underlies impaired lymphoid development during aging . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(22):e2302019120.
Johnson EL , Lin JJ, King-Stephens D, Weber PB, Laxer KD, Saez I, Girgis F, D'Esposito M, Knight RT, Badre D. A rapid theta network mechanism for flexible information encoding . Nature Communications . 2023;14(1):2872.Khan SS , Post WS, Guo X, Tan J, Zhu F, Bos D, Sedaghati-Khayat B, van Rooij J, Aday A, Allen NB , Bos MM, Uitterlinden AG, Budoff MJ, Lloyd-Jones DM , Mosley JD, Rotter JI, Greenland P , Kavousi M. Coronary Artery Calcium Score and Polygenic Risk Score for the Prediction of Coronary Heart Disease Events . JAMA . 2023;329(20):1768-1777.Khramtsova EA, Wilson MA, Martin J, Winham SJ, He KY, Davis LK, Stranger BE . Quality control and analytic best practices for testing genetic models of sex differences in large populations . Cell . 2023;186(10):2044-2061.
Perrault EN, Shireman JM, Ali ES, Lin P, Preddy I, Park C, Budhiraja S, Baisiwala S, Dixit K, James CD, Heiland DH, Ben-Sahra I , Pott S, Basu A, Miska J, Ahmed AU . Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production . Science Advances . 2023;9(20):eade7236.
Quijada P, Park S, Zhao P, Kolluri KS, Wong D, Shih KD, Fang K, Pezhouman A, Wang L, Daraei A, Tran MD, Rathbun EM, Burgos Villar KN, Garcia-Hernandez ML, Pham TT, Lowenstein CJ, Iruela-Arispe ML , Carmichael ST, Small EM, Ardehali R. Cardiac pericytes mediate the remodeling response to myocardial infarction . Journal of Clinical Investigation . 2023;133(10).
Sarkar MK, Uppala R, Zeng C, Billi AC, Tsoi LC, Kidder A, Xing X, Perez White BE, Shao S, Plazyo O, Sirobhushanam S, Xing E, Jiang Y, Gallagher KA, Voorhees JJ, Kahlenberg JM, Gudjonsson JE. Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction . Journal of Clinical Investigation . 2023;133(9).
Siderowf A, Concha-Marambio L, Lafontant DE, Farris CM, Ma Y, Urenia PA, Nguyen H, Alcalay RN, Chahine LM, Foroud T, Galasko D, Kieburtz K, Merchant K , Mollenhauer B, Poston KL, Seibyl J, Simuni T, Tanner CM, Weintraub D, Videnovic A, Choi SH, Kurth R, Caspell-Garcia C, Coffey CS, Frasier M, Oliveira LMA, Hutten SJ, Sherer T, Marek K, Soto C. Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study . Lancet Neurology . 2023;22(5):407-417.
Sonabend AM, Gould A, Amidei C, Ward R, Schmidt KA, Zhang DY, Gomez C, Bebawy JF, Liu BP, Bouchoux G, Desseaux C, Helenowski IB, Lukas RV, Dixit K, Kumthekar P, Arrieta VA, Lesniak MS , Carpentier A, Zhang H, Muzzio M, Canney M, Stupp R . Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial. Lancet Oncology . 2023;24(5):509-522.
Sorajja P, Whisenant B, Hamid N, Naik H, Makkar R, Tadros P, Price MJ, Singh G, Fam N, Kar S, Schwartz JG, Mehta S, Bae R, Sekaran N, Warner T, Makar M, Zorn G, Spinner EM, Trusty PM, Benza R, Jorde U, McCarthy P, Thourani V, Tang GHL, Hahn RT, Adams DH. Transcatheter Repair for Patients with Tricuspid Regurgitation . New England Journal of Medicine . 2023;388(20):1833-1842.
Vien TN, Ta MC, Kimura LF, Onay T, DeCaen PG . Primary cilia TRP channel regulates hippocampal excitability . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(22):e2219686120.Wang J, Fu Y, Huang W, Biswas R, Banerjee A, Broussard JA, Zhao Z, Wang D , Bjerke G, Raghavan S, Yan J, Green KJ, Yi R. MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(22):e2220635120.Wu RF, Park J, Qian YY, Shi ZX, Hu RC, Yuan YX, Xiong SL, Wang ZL, Yan GG, Ong SG, Song Q, Song ZY, Mahmoud AM, Xu PW, He CC , Arpke RW, Kyba M, Shu G, Jiang QY, Jiang YW. Genetically prolonged beige fat in male mice confers long-lasting metabolic health . Nature Communications . 2023;14(1):17.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L. The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes . Nature Communications . 2023;14(1):3132.
Hou K, Ding Y, Xu Z, Wu Y, Bhattacharya A, Mester R, Belbin GM, Buyske S, Conti DV, Darst BF, Fornage M, Gignoux C, Guo X, Haiman C, Kenny EE, Kim M, Kooperberg C, Lange L, Manichaikul A, North KE, Peters U, Rasmussen-Torvik LJ , Rich SS, Rotter JI, Wheeler HE, Wojcik GL, Zhou Y, Sankararaman S, Pasaniuc B. Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals . Nature Genetics . 2023;55(4):549-558.
Kinnamon DD, Jordan E, Haas GJ, Hofmeyer M, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Tang WHW, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE , Katz S, Pan S, Jimenez J, Aaronson KD, Fishbein DP, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Mead JO, Huggins GS, Ni H, Burke W, Hershberger RE. Effectiveness of the Family Heart Talk Communication Tool in Improving Family Member Screening for Dilated Cardiomyopathy: Results of a Randomized Trial . Circulation . 2023;147(17):1281-1290.
Kuramoto K, Liang H, Hong JH, He C. Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise . Cell Metabolism . 2023;35(4):620-632.e5.Mentias A, Peterson ED, Keshvani N, Kumbhani DJ, Yancy CW , Morris AA, Allen LA, Girotra S, Fonarow GC, Starling RC, Alvarez P, Desai MY, Cram P, Pandey A. Achieving Equity in Hospital Performance Assessments Using Composite Race-Specific Measures of Risk-Standardized Readmission and Mortality Rates for Heart Failure . Circulation . 2023;147(15):1121-1133.
Obeidat AM, Wood MJ, Adamczyk NS, Ishihara S, Li J, Wang L, Ren D, Bennett DA, Miller RJ , Malfait AM, Miller RE. Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis . Nature Communications . 2023;14(1):2479.
Pacheco LD, Clifton RG, Saade GR, Weiner SJ, Parry S, Thorp JM, Jr., Longo M, Salazar A, Dalton W, Tita ATN, Gyamfi-Bannerman C, Chauhan SP, Metz TD, Rood K, Rouse DJ, Bailit JL, Grobman WA , Simhan HN, Macones GA. Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery . New England Journal of Medicine . 2023;388(15):1365-1375.
Robertson AG, Meghani K, Cooley LF, McLaughlin KA, Fall LA, Yu Y, Castro MAA, Groeneveld CS, de Reyniès A, Nazarov VI, Tsvetkov VO, Choy B, Raggi D, Marandino L, Montorsi F, Powles T, Necchi A, Meeks JJ . Expression-based subtypes define pathologic response to neoadjuvant immune-checkpoint inhibitors in muscle-invasive bladder cancer . Nature Communications . 2023;14(1):2126.
Shenderov E, De Marzo AM, Lotan TL, Wang H, Chan S, Lim SJ, Ji H, Allaf ME, Chapman C, Moore PA, Chen F, Sorg K, White AM, Church SE, Hudson B, Fields PA, Hu S, Denmeade SR, Pienta KJ, Pavlovich CP, Ross AE , Drake CG, Pardoll DM, Antonarakis ES. Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial . Nature Medicine . 2023;29(4):888-897.
Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME, Smith R, Morales A, Stumpf L, McGrath K, Krainc D, Mendillo ML, Prakriya M, Chandel NS, Caraveo G. Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(17):e2217396120.Solé-Navais P, Flatley C, Steinthorsdottir V, Vaudel M, Juodakis J, Chen J, Laisk T, LaBella AL, Westergaard D, Bacelis J, Brumpton B, Skotte L, Borges MC, Helgeland Ø, Mahajan A, Wielscher M, Lin F, Briggs C, Wang CA, Moen GH, Beaumont RN, Bradfield JP, Abraham A, Thorleifsson G, Gabrielsen ME, Ostrowski SR, Modzelewska D, Nohr EA, Hypponen E, Srivastava A, Talbot O , Allard C, Williams SM, Menon R, Shields BM, Sveinbjornsson G, Xu H, Melbye M, Lowe W, Jr ., Bouchard L, Oken E, Pedersen OB, Gudbjartsson DF, Erikstrup C, Sørensen E, Lie RT, Teramo K, Hallman M, Juliusdottir T, Hakonarson H, Ullum H, Hattersley AT, Sletner L, Merialdi M, Rifas-Shiman SL, Steingrimsdottir T, Scholtens D, Power C, West J, Nyegaard M, Capra JA, Skogholt AH, Magnus P, Andreassen OA, Thorsteinsdottir U, Grant SFA, Qvigstad E, Pennell CE, Hivert MF, Hayes GM , Jarvelin MR, McCarthy MI, Lawlor DA, Nielsen HS, Mägi R, Rokas A, Hveem K, Stefansson K, Feenstra B, Njolstad P, Muglia LJ, Freathy RM, Johanson S, Zhang G, Jacobsson B. Genetic effects on the timing of parturition and links to fetal birth weight . Nature Genetics . 2023;55(4):559-567.
Yuan Y, Jin A, Neal B, Feng X, Qiao Q, Wang H, Zhang R, Li J, Duan P, Cao L, Zhang H, Hu S, Li H, Gao P, Xie G, Yuan J, Cheng L, Wang S, Zhang H, Niu W, Fang H, Zhao M, Gao R, Chen J, Elliott P, Labarthe D , Wu Y. Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial . Nature Medicine . 2023;29(4):973-981.
Burdett KB, Unruh D, Drumm M, Steffens A , Lamano J, Judkins J, Schwartz M, Javier R, Amidei C , Lipp ES, Peters KB, Lai A, Eldred BSC, Heimberger AB, McCortney K, Scholtens DM, Horbinski C. Determining venous thromboembolism risk in patients with adult-type diffuse glioma . Blood . 2023;141(11):1322-1336.Burgdorf JS, Yoon S, Dos Santos M, Lammert CR, Moskal JR, Penzes P. An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome . Molecular Psychiatry . 2023;28(3):1101-1111.
Dmello C, Zhao J, Chen L, Gould A, Castro B, Arrieta VA, Zhang DY, Kim KS, Kanojia D, Zhang P, Miska J, Yeeravalli R, Habashy K, Saganty R, Kang SJ, Fares J , Liu C, Dunn G, Bartom E, Schipma MJ , Hsu PD, Alghamri MS, Lesniak MS, Heimberger AB, Rabadan R, Lee-Chang C, Sonabend AM. Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade . Nature Communications . 2023;14(1):1566.Eichner LJ, Curtis SD, Brun SN, McGuire CK, Gushterova I , Baumgart JT, Trefts E, Ross DS, Rymoff TJ, Shaw RJ. HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non-small cell lung cancer . Science Advances . 2023;9(11):eadd3243.
Fisher SA, Stetson BT, Kominiarek MA. Pregnancy After Bariatric Surgery . JAMA . 2023;329(9):758-759.Han X, Mei Y, Mishra RK, Bi H, Jain AD, Schiltz GE , Zhao B, Sukhanova M, Wang P, Grigorescu AA, Weber PC, Piwinski JJ, Prado MA, Paulo JA, Stephens L, Anderson KE, Abrams CS, Yang J, Ji P. Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models. Journal of Clinical Investigation . 2023;133(6).
Jang H, Li Y, Fung AA, Bagheri P, Hoang K, Skowronska-Krawczyk D, Chen X, Wu JY , Bintu B, Shi L. Super-resolution SRS microscopy with A-PoD . Nature Methods . 2023;20(3):448-458.
Jiménez-Gómez B, Ortega-Sáenz P, Gao L, González-Rodríguez P, García-Flores P, Chandel N, López-Barneo J. Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice . Nature Communicaitons . 2023;14(1):1172.
Karlikow M, Amalfitano E, Yang X, Doucet J, Chapman A, Mousavi PS, Homme P, Sutyrina P, Chan W, Lemak S, Yakunin AF, Dolezal AG, Kelley S, Foster LJ, Harpur BA, Pardee K. CRISPR-induced DNA reorganization for multiplexed nucleic acid detection . Nature Communications . 2023;14(1):1505.
Kunz PL, Graham NT, Catalano PJ, Nimeiri HS, Fisher GA, Longacre TA, Suarez CJ, Martin BA, Yao JC, Kulke MH, Hendifar AE, Shanks JC, Shah MH, Zalupski MM, Schmulbach EL, Reidy-Lagunes DL, Strosberg JR, O'Dwyer PJ, Benson AB . Randomized Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors (ECOG-ACRIN E2211). Journal of Clinical Oncology . 2023;41(7):1359.
Luo Y, Abidian MR, Ahn JH, et al. (including Roger JA ) Technology Roadmap for Flexible Sensors . ACS Nano . 2023;17(6):5211-5295.
Motzer RJ, Russo P, Grünwald V, Tomita Y, Zurawski B, Parikh O, Buti S, Barthélémy P, Goh JC, Ye D, Lingua A, Lattouf JB, Albigès L, George S, Shuch B, Sosman J , Staehler M, Vázquez Estévez S, Simsek B, Spiridigliozzi J, Chudnovsky A, Bex A. Adjuvant nivolumab plus ipilimumab versus placebo for localised renal cell carcinoma after nephrectomy (CheckMate 914): a double-blind, randomised, phase 3 trial. Lancet . 2023;401(10379):821-832.
Pancani T, Day M, Tkatch T, Wokosin DL, González-Rodríguez P, Kondapalli J, Xie Z, Chen Y, Beaumont V, Surmeier DJ. Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice . Nature Communications . 2023;14(1):1398.Patel SP, Othus M, Chen Y, Wright GP, Jr., Yost KJ, Hyngstrom JR, Hu-Lieskovan S, Lao CD, Fecher LA, Truong TG, Eisenstein JL, Chandra S, Sosman JA , Kendra KL, Wu RC, Devoe CE, Deutsch GB, Hegde A, Khalil M, Mangla A, Reese AM, Ross MI, Poklepovic AS, Phan GQ, Onitilo AA, Yasar DG, Powers BC, Doolittle GC, In GK, Kokot N, Gibney GT, Atkins MB, Shaheen M, Warneke JA, Ikeguchi A, Najera JE, Chmielowski B, Crompton JG, Floyd JD, Hsueh E, Margolin KA, Chow WA, Grossmann KF, Dietrich E, Prieto VG, Lowe MC, Buchbinder EI, Kirkwood JM, Korde L, Moon J, Sharon E, Sondak VK, Ribas A. Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma . New England Journal of Medicine . 2023;388(9):813-823.
Poor TA, Chandel NS. SnapShot: Mitochondrial signaling . Molecular Cell . 2023;83(6):1012-1012.e1.Soliman SHA, Cisneros WJ, Iwanaszko M, Aoi Y, Ganesan S, Walter M, Zeidner JM, Mishra RK, Kim EY, Wolinsky SM, Hultquist JF, Shilatifard A . Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C . Science Advances . 2023;9(10):eadf2468.Takahashi S, Zhou Y, Kojima T, Cheatham MA, Homma K . Prestin's fast motor kinetics is essential for mammalian cochlear amplification . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(11):e2217891120.
Wang X, Singh P, Zhou L, Sharafeldin N, Landier W, Hageman L, Burridge P , Yasui Y, Sapkota Y, Blanco JG, Oeffinger KC, Hudson MM, Chow EJ, Armenian SH, Neglia JP, Ritchey AK, Hawkins DS, Ginsberg JP, Robison LL, Armstrong GT, Bhatia S. Genome-Wide Association Study Identifies ROBO2 as a Novel Susceptibility Gene for Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors . Journal of Clinical Oncology . 2023;41(9):1758-1769.
Wculek SK, Heras-Murillo I, Mastrangelo A, Mañanes D, Galán M, Miguel V, Curtabbi A, Barbas C, Chandel NS , Enríquez JA, Lamas S, Sancho D. Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis . Immunity . 2023;56(3):516-530.e9.
Zador A, Escola S, Richards B, Ölveczky B, Bengio Y, Boahen K, Botvinick M, Chklovskii D, Churchland A, Clopath C, DiCarlo J, Ganguli S, Hawkins J, Körding K, Koulakov A, LeCun Y, Lillicrap T, Marblestone A, Olshausen B, Pouget A, Savin C, Sejnowski T, Simoncelli E, Solla S , Sussillo D, Tolias AS, Tsao D. Catalyzing next-generation Artificial Intelligence through NeuroAI . Nature Communications . 2023;14(1):1597.
Zhang P, Rashidi A , Zhao J, Silvers C, Wang H, Castro B, Ellingwood A, Han Y, Lopez-Rosas A, Zannikou M, Dmello C, Levine R, Xiao T, Cordero A, Sonabend AM, Balyasnikova IV, Lee-Chang C, Miska J, Lesniak MS. STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma . Nature Communications . 2023;14(1):1610.Zhang Y, Liu F, Zhang Y, Wang J, D'Andrea D, Walters JB, Li S, Yoon HJ, Wu M, Li S, Hu Z, Wang T, Choi J, Bailey K, Dempsey E, Zhao K, Lantsova A, Bouricha Y, Huang I, Guo H, Ni X, Wu Y, Lee G, Jiang F, Huang Y, Franz CK, Rogers JA. Self-powered, light-controlled, bioresorbable platforms for programmed drug delivery. Proceedings of the National Academy of Sciences of the United States of America . 2023;120(11):e2217734120.
Zou H, Poore B, Brown EE, Qian JQ, Xie B, Asimakidou E, Razskazovskiy V, Ayrapetian D, Sharma V, Xia SJ, Liu F, Chen AP, Guan YC, Li ZW, Wanggou S, Saulnier O, Ly M, Fellows-Mayle W, Xi GF, Tomita T , Resnick AC, Mack SC, Raabe EH, Eberhart CG, Sun DD, Stronach BE, Agnihotri S, Kohanbash G, Lu SJ, Herrup K, Rich JN, Gittes GK, Broniscer A, Hu ZL, Li XJ, Pollack IF, Friedlander RM, Hainer SJ, Taylor MD, Hu BL. A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis . Nature Cell Biology . 2023;25(3):493
Álvarez Z, Ortega JA , Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, Papakis V, Syrgiannis Z, Sather NA, Musumeci C, Engel E, Stupp SI, Kiskinis E . Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons . Cell Stem Cell . 2023;30(2):219-238.e14. Bass J, Tschöp MH, Beutler LR . Dual gut hormone receptor agonists for diabetes and obesity. Journal of Clinical Investigation . 2023;133(3). Cox J , Minerva AR, Fleming WT, Zimmerman CA, Hayes C, Zorowitz S, Bandi A, Ornelas S, McMannon B, Parker NF, Witten IB. A neural substrate of sex-dependent modulation of motivation . Nature Neuroscience . 2023;26(2):274-284. Esarte Palomero O, Larmore M, DeCaen PG . Polycystin Channel Complexes . Annual Review of Physiology . 2023;85:425-448. Forrest MP, Dos Santos M, Piguel NH, Wang YZ, Hawkins NA, Bagchi VA, Dionisio LE, Yoon S, Simkin D, Martin-de-Saavedra MD, Gao R, Horan KE, George AL, Jr., LeDoux MS, Kearney JA, Savas JN, Penzes P. Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub . Nature Communications . 2023;14(1):825. Jeong H, Yoo JY, Ouyang W, Greane A, Wiebe AJ, Huang I, Lee YJ, Lee JY, Kim J, Ni X, Kim S, Huynh HL, Zhong I, Chin YX, Gu J, Johnson AM, Brancaccio T, Rogers JA. Closed-loop network of skin-interfaced wireless devices for quantifying vocal fatigue and providing user feedback . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(9):e2219394120. Kazenwadel J, Venugopal P, Oszmiana A, Toubia J, Arriola-Martinez L, Panara V, Piltz SG, Brown C, Ma W , Schreiber AW, Koltowska K, Taoudi S, Thomas PQ, Scott HS, Harvey NL. A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature . Nature . 2023;614(7947):343-348. Krüger A, Watkins AM, Wellington-Oguri R, Romano J, Kofman C, DeFoe A, Kim Y, Anderson-Lee J, Fisker E, Townley J, d'Aquino AE, Das R, Jewett MC . Community science designed ribosomes with beneficial phenotypes . Nature Communications . 2023;14(1):961.
Lee-Chang C, Lesniak MS. Next-generation antigen-presenting cell immune therapeutics for gliomas . Journal of Clinical Investigation . 2023;133(3). Lotfollahi M, Rybakov S, Hrovatin K, Hediyeh-Zadeh S, Talavera-López C, Misharin AV, Theis FJ. Biologically informed deep learning to query gene programs in single-cell atlases . Nature Cell Biology . 2023;25(2):337-350. Maturi RK, Glassman AR, Josic K, Baker CW, Gerstenblith AT, Jampol LM , Meleth A, Martin DF, Melia M, Punjabi OS, Rofagha S, Salehi-Had H, Stockdale CR, Sun JK. Four-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy . JAMA . 2023;329(5):376-385. Papi A, Ison MG , Langley JM, Lee DG, Leroux-Roels I, Martinon-Torres F, Schwarz TF, van Zyl-Smit RN, Campora L, Dezutter N, de Schrevel N, Fissette L, David MP, Van der Wielen M, Kostanyan L, Hulstrøm V. Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults. New England Journal of Medicine . 2023;388(7):595-608. Park M, Yoo JY, Yang T, Jung YH, Vázquez-Guardado A, Li S, Kim JH, Shin J, Maeng WY, Lee G, Yoo S, Luan H, Kim JT, Shin HS, Flavin MT, Yoon HJ, Miljkovic N, Huang Y, King WP, Rogers JA. Skin-integrated systems for power efficient, programmable thermal sensations across large body areas . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(6):e2217828120.
Piccinin C, Basch E, Bhatnagar V, Calvert M, Campbell A, Cella D , Cleeland CS, Coens C, Darlington AS, Dueck AC, Groenvold M, Herold R, King-Kallimanis BL, Kluetz PG, Kuliś D, O'Connor D, Oliver K, Pe M, Reeve BB, Reijneveld JC, Wang XS, Bottomley A. Recommendations on the use of item libraries for patient-reported outcome measurement in oncology trials: findings from an international, multidisciplinary working group. Lancet Oncology . 2023;24(2):e86-e95. Song JW, Ryu H, Bai W, Xie Z, Vázquez-Guardado A, Nandoliya K, Avila R, Lee G, Song Z, Kim J, Lee MK, Liu Y, Kim M, Wang H, Wu Y, Yoon HJ, Kwak SS, Shin J, Kwon K, Lu W, Chen X, Huang Y, Ameer GA, Rogers JA . Bioresorbable, wireless, and battery-free system for electrotherapy and impedance sensing at wound sites . Science Advances . 2023;9(8):eade4687. Tsien CI, Pugh SL, Dicker AP, Raizer JJ , Matuszak MM, Lallana EC, Huang J, Algan O, Deb N, Portelance L, Villano JL, Hamm JT, Oh KS, Ali AN, Kim MM, Lindhorst SM, Mehta MP. NRG Oncology/RTOG1205: A Randomized Phase II Trial of Concurrent Bevacizumab and Reirradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma . Journal of Clinical Oncology . 2023;41(6):1285-1295. Wang X, Vaduganathan M, Claggett BL, Hegde SM, Pabon M, Kulac IJ, Vardeny O, O'Meara E, Zieroth S, Katova T, McGrath MM, Pouleur AC, Jhund PS, Desai AS, Inzucchi SE, Kosiborod MN, de Boer RA, Kober L, Sabatine MS, Martinez FA, Ponikowski P, Shah SJ , Hernandez AF, Langkilde AM, McMurray JJV, Solomon SD, Lam CSP. Sex Differences in Characteristics, Outcomes, and Treatment Response With Dapagliflozin Across the Range of Ejection Fraction in Patients With Heart Failure: Insights From DAPA-HF and DELIVER . Circulation . 2023;147(8):624-634. Webber JL, García-Añoveros J . Precision patterning: How inner hair cells "hop" to it . Science Advances . 2023;9(8):eadg8662. Yoo S, Yang T, Park M, Jeong H, Lee YJ, Cho D, Kim J, Kwak SS, Shin J, Park Y, Wang Y, Miljkovic N, King WP, Rogers JA. Responsive materials and mechanisms as thermal safety systems for skin-interfaced electronic devices . Nature Communications . 2023;14(1):1024. Zhao Q, Hu J, Kong L, Jiang S, Tian X, Wang J, Hashizume R , Jia Z, Fowlkes NW, Yan J, Xia X, Yi SF, Dao LH, Masopust D, Heimberger AB, Li S. FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells . Nature Communications . 2023;14(1):735.
Amici DR, Cingoz H, Alasady MJ, Alhayek S, Phoumyvong CM , Sahni N, Yi SS, Mendillo ML . The HAPSTR2 retrogene buffers stress signaling and resilience in mammals . Nature Communications . 2023;14(1):152.Arrieta VA, Dmello C, McGrail DJ, Brat DJ, Lee-Chang C, Heimberger AB , Chand D, Stupp R, Sonabend AM . Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment . Journal of Clinical Investigation . 2023;133(2).Atkins MB, Lee SJ, Chmielowski B, Tarhini AA, Cohen GI, Truong TG, Moon HH, Davar D, O'Rourke M, Stephenson JJ, Curti BD, Urba WJ, Brell JM, Funchain P, Kendra KL, Ikeguchi AP, Jaslowski A, Bane CL, Taylor MA, Bajaj M, Conry RM, Ellis RJ, Logan TF, Laudi N, Sosman JA , Crockett DG, Pecora AL, Okazaki IJ, Reganti S, Chandra S , Guild S, Chen HX, Streicher HZ, Wolchok JD, Ribas A, Kirkwood JM. Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134 . Journal of Clinical Oncology . 2023;41(2):186-197.
Brastianos PK, Twohy EL, Gerstner ER, Kaufmann TJ, Iafrate AJ, Lennerz J, Jeyapalan S, Piccioni DE, Monga V, Fadul CE, Schiff D, Taylor JW, Chowdhary SA, Bettegowda C, Ansstas G, De La Fuente M, Anderson MD, Shonka N, Damek D, Carrillo J, Kunschner-Ronan LJ, Chaudhary R, Jaeckle KA, Senecal FM, Kaley T, Morrison T, Thomas AA, Welch MR, Iwamoto F, Cachia D, Cohen AL, Vora S, Knopp M, Dunn IF, Kumthekar P , Sarkaria J, Geyer S, Carrero XW, Martinez-Lage M, Cahill DP, Brown PD, Giannini C, Santagata S, Barker FG, 2nd, Galanis E. Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations . Journal of Clinical Oncology . 2023;41(3):618-628.
Chehab L, Doody DR, Esbenshade AJ, Guilcher GMT, Dvorak CC, Fisher BT, Mueller BA, Chow EJ, Rossoff J . A Population-Based Study of the Long-Term Risk of Infections Associated With Hospitalization in Childhood Cancer Survivors . Journal of Clinical Oncology . 2023;41(2):364-372.
Chen D, Berona J , Chan YM, Ehrensaft D, Garofalo R, Hidalgo MA, Rosenthal SM, Tishelman AC, Olson-Kennedy J. Psychosocial Functioning in Transgender Youth after 2 Years of Hormones . New England Journal of Medicine . 2023;388(3):240-250.
Chen H, Bai Y, Kobayashi M, Xiao S, Cai W, Barajas S, Chen S, Miao J, Meke FN, Vemula S, Ropa JP, Croop JM, Boswell HS, Wan J, Jia Y, Liu H, Li LS, Altman JK, Eklund EA, Ji P , Tong W, Band H, Huang DT, Platanias LC , Zhang ZY, Liu Y . PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371 . Blood . 2023;141(3):244-259.de Botton S, Montesinos P, Schuh AC, Papayannidis C, Vyas P, Wei AH, Ommen H, Semochkin S, Kim HJ, Larson RA, Koprivnikar J, Frankfurt O , Thol F, Chromik J, Byrne J, Pigneux A, Thomas X, Salamero O, Vidriales MB, Doronin V, Döhner H, Fathi AT, Laille E, Yu X, Hasan M, Martin-Regueira P, DiNardo CD. Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial . Blood . 2023;141(2):156-167.
Erwin GS, Gürsoy G, Al-Abri R, Suriyaprakash A, Dolzhenko E, Zhu K, Hoerner CR, White SM, Ramirez L, Vadlakonda A, Vadlakonda A, von Kraut K, Park J, Brannon CM, Sumano DA, Kirtikar RA, Erwin AA , Metzner TJ, Yuen RKC, Fan AC, Leppert JT, Eberle MA, Gerstein M, Snyder MP. Recurrent repeat expansions in human cancer genomes . Nature . 2023;613(7942):96-102.
Ezpeleta M, Gabel K, Cienfuegos S, Kalam F, Lin S, Pavlou V, Song Z, Haus JM, Koppe S, Alexandria SJ , Tussing-Humphreys L, Varady KA. Effect of alternate day fasting combined with aerobic exercise on non-alcoholic fatty liver disease: A randomized controlled trial. Cell Metabolism . 2023;35(1):56-70.e3.
Fu Z, Chen S, Zhu Y, Zhang D, Xie P , Jiao Q, Chi J, Xu S, Xue Y, Lu X, Song X, Cristofanilli M, Gradishar WJ , Kalinsky K, Yin Y, Zhang B, Wan Y. Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity . Science Advances . 2023;9(1):eadd6626.Hoffmann JA, Attridge MM, Carroll MS, Simon NE , Beck AF, Alpern ER. Association of Youth Suicides and County-Level Mental Health Professional Shortage Areas in the US . JAMA Pediatrics . 2023;177(1):71-80.Huang Y, Shan Y, Zhang W, Lee AM, Li F, Stranger BE , Huang RS. Deciphering genetic causes for sex differences in human health through drug metabolism and transporter genes . Nature Communications . 2023;14(1):175.
Jastreboff AM, Kushner RF . New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics . Annual Review of Medicine . 2023;74:125-139.
Kraft SA, Rohrig A, Williams A, Shah SK . Better recognition for research participants: what society should learn from covid-19 . BMJ . 2023;380:e071178.
Ladin K, Tighiouart H, Bronzi O, Koch-Weser S, Wong JB, Levine S, Agarwal A, Ren L, Degnan J, Sewall LN, Kuramitsu B, Fox P, Gordon EJ, Isakova T , Rifkin D, Rossi A, Weiner DE. Effectiveness of an Intervention to Improve Decision Making for Older Patients With Advanced Chronic Kidney Disease : A Randomized Controlled Trial . Annals of Internal Medicine . 2023;176(1):29-38.
Michieletto MF, Tello-Cajiao JJ, Mowel WK, Chandra A, Yoon S, Joannas L, Clark ML, Jimenez MT, Wright JM, Lundgren P, Williams A, Thaiss CA, Vahedi G, Henao-Mejia J. Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation . Nature Immunology. 2023;24(1):42-54.
Miska J, Chandel NS. Targeting fatty acid metabolism in glioblastoma . Journal of Clinical Investigation . 2023;133(1)Morris VK, Kennedy EB, Baxter NN, Benson AB, 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C. Treatment of Metastatic Colorectal Cancer: ASCO Guideline . Journal of Clinical Oncology . 2023;41(3):678-700.
Nair A, Karigo T, Yang B, Ganguli S, Schnitzer MJ, Linderman SW, Anderson DJ, Kennedy A . An approximate line attractor in the hypothalamus encodes an aggressive state . Cell . 2023;186(1):178-193.e15.
Natori A, Sookdeo VD, Koru-Sengul T, Schlumbrecht M, Calfa CL, Maclntyre J, Benzo RM, Moreno PI, Crane TE, Garcia SF , Penedo FJ. Symptoms and Needs Monitoring in Diverse Ambulatory Oncology Patients: Usage Characteristics and Impact on Emergency Room Visits and Hospitalization . Journal of Clinical Oncology . 2023;41(2):285-294.
Paluch AE, Bajpai S, Ballin M, Bassett DR, Buford TW, Carnethon MR , Chernofsky A, Dooley EE, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kong L, Kraus WE, Larson MG, Lee IM, Matthews CE, Newton RL, Jr., Nordström A, Nordström P, Palta P, Patel AV, Pettee Gabriel K, Pieper CF, Pompeii L, Rees-Punia E, Spartano NL, Vasan RS, Whincup PH, Yang S, Fulton JE. Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis . Circulation . 2023;147(2):122-131.
Rugo HS, Im SA, Cardoso F, Cortes J, Curigliano G, Musolino A, Pegram MD, Bachelot T, Wright GS, Saura C, Escrivá-de-Romaní S, De Laurentiis M, Schwartz GN, Pluard TJ, Ricci F, Gwin WR, 3rd, Levy C, Brown-Glaberman U, Ferrero JM, de Boer M, Kim SB, Petráková K, Yardley DA, Freedman O, Jakobsen EH, Gal-Yam EN, Yerushalmi R, Fasching PA, Kaufman PA, Ashley EJ, Perez-Olle R, Hong S, Rosales MK, Gradishar WJ . Margetuximab Versus Trastuzumab in Patients With Previously Treated HER2-Positive Advanced Breast Cancer (SOPHIA): Final Overall Survival Results From a Randomized Phase 3 Trial. Journal of Clinical Oncology . 2023;41(2):198-205.
Schwamm LH, Kamel H, Granger CB, Piccini JP, Katz JM, Sethi PP, Sidorov EV, Kasner SE, Silverman SB, Merriam TT, Franco N, Ziegler PD, Bernstein RA . Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: A Prespecified Secondary Analysis of the STROKE AF Randomized Clinical Trial. JAMA Neurology . 2023;80(1):99-103.
Shah NS, Huang X, Petito LC, Bancks MP, Ning H, Cameron NA, Kershaw KN, Kandula NR, Carnethon MR, Lloyd-Jones DM, Khan SS. Social and Psychosocial Determinants of Racial and Ethnic Differences in Cardiovascular Health in the United States Population . Circulation . 2023;147(3):190-200.Sorror ML, Gooley TA, Storer BE, Gerds AT, Sekeres MA, Medeiros BC, Wang ES, Shami PJ, Adekola K, Luger S, Baer MR, Rizzieri DA, Wildes TM, Koprivnikar J, Smith J, Garrison M, Kojouri K, Schuler TA, Leisenring WM, Onstad LE, Becker PS, McCune JS, Lee SJ, Sandmaier BM, Appelbaum FR, Estey EH. An 8-year pragmatic observation evaluation of the benefits of allogeneic HCT in older and medically infirm patients with AML . Blood . 2023;141(3):295-308.
Stuart T, Jeang WJ, Slivicki RA, Brown BJ, Burton A, Brings VE, Alarcón-Segovia LC, Agyare P, Ruiz S, Tyree A, Pruitt L, Madhvapathy S, Niemiec M, Zhuang J, Krishnan S, Copits BA, Rogers JA , Gereau RWt, Samineni VK, Bandodkar AJ, Gutruf P. Wireless, Battery-Free Implants for Electrochemical Catecholamine Sensing and Optogenetic Stimulation . ACS Nano . 2023;17(1):561-574.
Tamadonfar KO, Di Venanzio G, Pinkner JS, Dodson KW, Kalas V , Zimmerman MI, Bazan Villicana J, Bowman GR, Feldman MF, Hultgren SJ. Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(4):e2212694120.
Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D , Huang YM, Zhang K, Shah YM, Sun S. Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin . Proceedings of the National Academy of Sciences of the United States of America . 2023;120(2):e2212644120.
Tsujikawa S, DeMeulenaere KE, Centeno MV, Ghazisaeidi S, Martin ME, Tapies MR, Maneshi MM, Yamashita M , Stauderman KA, Apkarian AV, Salter MW, Prakriya M . Regulation of neuropathic pain by microglial Orai1 channels . Science Advances . 2023;9(4):eade7002.
Zhou Y, Liu Y, Gupta S, Paramo MI, Hou Y, Mao C, Luo Y , Judd J, Wierbowski S, Bertolotti M, Nerkar M, Jehi L, Drayman N, Nicolaescu V, Gula H, Tay S, Randall G, Wang P, Lis JT, Feschotte C, Erzurum SC, Cheng F, Yu H. A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets . Nature Biotechnology . 2023;41(1):128-139.