News and Announcements

Northwestern Medicine scientists have discovered how a protein in a deadly type of lung cancer can control how the immune system responds to the tumor, according to a study published in the Proceedings of the National Academy of Sciences.

Investigators from the laboratory of Marc Mendillo, PhD, have discovered new cellular regulators of an established cancer cell transcription factor linked to cancer cell resilience and tumor progression, according to findings published in the Proceedings of the National Academy of Sciences.

The COVID-19 virus spreads via mucus once inside an infected airway, according to a Northwestern Medicine study published in Nature Communications.

Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.

Investigators led by Pablo Penaloza-MacMaster, PhD, associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA vaccination significantly improved vaccine efficacy in mice, according to findings published in The Journal of Clinical Investigation.

Rex Chisholm, PhD, vice dean for Scientific Affairs and Graduate Education, kicked off this year’s celebration by welcoming attendees and presenting the Tripartite Legacy Faculty Prize in Translational Science and Education to Alan Hauser, MD, PhD, professor and vice chair of Microbiology-Immunology, and the Medical Faculty Council Mentors of the Year awards to Hauser and Scott Budinger, MD, chief of Pulmonary and Critical Care in the Department of Medicine.

In research published in Science Advances, scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington’s disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.

Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.

An international team of investigators have discovered that oligodendrocytes contribute approximately one-third of plaque formation alongside neurons in mouse models of Alzheimer’s disease, according to a recent study published in Nature Neuroscience.