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Kutys Group

Matthew Kutys headshot

Matthew Kutys, PhD

Assistant Professor
Department of Cell and Tissue Biology
Helen Diller Family Comprehensive Cancer Center
Cardiovascular Research Institute
Biomedical Sciences Graduate Program
UCSF/UCB Bioengineering Graduate Program

BOX 0512, 513 Parnassus Ave, HSW 613
San Francisco, CA 94143
matthew.kutys@ucsf.edu

The Kutys Lab develops and applies biomimetic human tissue models that incorporate three-dimensional organotypic architectures and permit the study of human tissue development, regeneration, and pathogenesis with high resolution and biological control. Combining these models with cellular and molecular technologies, a major focus of the laboratory is gaining mechanistic understanding of the orchestration of vascular morphogenesis and fate specification by endothelial mechanotransduction at cell-cell and cell-extracellular matrix interfaces.

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Anand Verma
Anand Verma
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Anand is a Junior Specialist in the Kutys Lab at UCSF. He received a B.S. in Biomolecular engineering from the University of California, Santa Cruz. While there, he worked in Dr. Rebecca DuBois’s lab as an undergraduate student where he completed his senior thesis on investigating the binding interactions between the RSV G glycoprotein and its human host cell receptor, CX3CR1. Currently, Anand’s work in the Kutys Lab centers around investigating the role of APP in the endothelium
Kyle Jacobs
Kyle Jacobs
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Kyle is a fourth year PhD candidate in the Kutys Lab at UCSF. Kyle completed his undergraduate studies in Biomedical Engineering and Mechanical Engineering at the University of California, Davis. While there, he investigated mechanisms by which mammalian cells sense and respond to mechanical forces in the laboratory of Dr. Soichiro Yamada. Kyle's thesis work in the Kutys Lab focuses on how contextual Rho GTPase signaling at endothelial cell-cell interfaces controls vascular barrier function.

Lakyn Mayo
Lakyn Mayo
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Lakyn is a graduate student in the Kutys lab at UCSF. She received a B.S. in Materials Science and Engineering in 2018 from Johns Hopkins University, where she concentrated in biomaterials and worked on engineering the blood-brain barrier in Dr. Peter Searson's lab. She joined the UCSF Medical Scientist Training Program in 2019 and the Kutys Lab in 2021 through the joint Bioengineering Graduate Program at UCSF and UC Berkeley. In the lab she studies endothelial cell-cell adhesion dynamics required for angiogenic initiation using microphysiological systems.
Lori Luo
Lori Luo
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Lori is a MD/PhD student at UCSF rotating in the Kutys Lab. She graduated from Columbia University studying Biomedical Engineering and is interested in tissue engineering.
Tania Singh
Tania Singh
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Tania is a graduate student in the Kutys lab at UCSF. She received both her B.S. and M.S in Biomedical Engineering in 2018 from The George Washington University, where she investigated the effect of therapeutic ultrasound on insulin secretion from pancreatic beta cells in Dr. Vesna Zderic's lab. She joined the joint Bioengineering Graduate Program at UCSF and UC Berkeley in 2019. Tania's thesis work in the Kutys lab focuses on how mechanical forces regulate the activation of the Notch1 receptor within the vascular endothelium.