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Phng Group

Li-Kun Phng headshot

Li-Kun Phng, PhD

Team Leader
Laboratory for Vascular Morphogenesis
RIKEN Center for Biosystems Dynamics Research (BDR)
2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe
650-0047, Japan
likun.phng@riken.jp

Li-Kun Phng is a Team Leader at RIKEN Center for Biosystems Dynamics Research, Kobe, Japan, where she heads the Laboratory for Vascular Morphogenesis. She obtained her PhD in 2009 from CRUK London Research Institute/University College London for her work on Notch signaling in sprouting angiogenesis. She then worked as a post-doctoral fellow in EMBL (Heidelberg, Germany), VIB/KU Leuven (Belgium) and NCVC (Japan). During this period, she unravelled how diverse actin structures control distinct steps of vessel morphogenesis. In October 2016, she started her own research group at the RIKEN Center for Developmental Biology. Her current research is aimed at understanding endothelial cell mechanobiology and the interplay between haemodynamic forces and endothelial cell mechanoresponse at cellular and subcellular levels.

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Haymar Wint
Haymar Wint
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Haymar Wint completed her MD degree at the University of Medicine 2, Yangon, Myanmar in 2009, following which she worked as a medical officer at North Okkala General Hospital. After that, she got her master’s degree in medical Biochemistry in 2017. Subsequently, she was awarded the MEXT scholarship, enabling her to pursue her doctoral studies at Okayama University in Japan, under the guidance of Professor Kohji Takei and Ass. Prof. Tetsuya Takeda, primarily focusing on collective cell migration in cancer metastasis.

Upon the completion of her PhD, Haymar joined Phng lab in Riken, BDR as a postdoctoral researcher, where she continues to dedicate her efforts towards unraveling the complexities of endothelial cell dynamics. Her current research endeavors revolve around investigating the responses of endothelial cells to shear stress and stretch stimuli, operating at both cellular and subcellular levels.

Igor Kondrychyn
Igor Kondrychyn
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Igor Kondrychyn graduated from Taras Shevchenko National University of Kyiv, followed by three-years postgraduate course in experimental oncology at Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology in Ukraine.

In 2008 he received his PhD in Developmental Biology from the National University of Singapore for his work on the roof plate and central canal morphogenesis in the developing spinal cord of zebrafish in the lab of Prof. Vladimir Korzh at the Institute of Molecular and Cell Biology (IMCB), Singapore. He then continued to work as a Postdoctoral Research Fellow in the same lab, studying a role of zic3 transcription factor in the early embryonic development. In 2013 he moved to the National Center for Biological Sciences (NCBS) in Bangalore, India, where he studied the function of autism risk genes in the zebrafish neurodevelopment.

In May 2017 Igor Kondrychyn joined the Phng lab at RIKEN BDR, Japan as a Research Scientist. His current project is focused on investigating how hydrostatic pressure regulates endothelial cell shape and migration during angiogenesis.

Yan Chen
Yan Chen
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Yan is currently a postdoctoral researcher in Dr. Li-Kun Phng's laboratory at the BDR Center of the RIKEN Institute in Japan. She is particularly interested in the regulation of blood vessel remodeling and the underlying cellular mechanisms. Her research focuses on understanding the roles of the actomyosin network in endothelial cell shape and size changes, which may lead to vessel remodeling. Yan obtained her PhD and master’s degrees from the University of Sheffield (UK), where she worked on molecular signaling pathways, such as VEGF and BMP, in endothelial cell migration and vessel remodeling. She was also involved in studying transcription factors in the regulation of hematopoietic stem cell differentiation.