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AASLD The Liver Meeting Abstracts & Presentations

The American Association for the Study of Liver Diseases hosts The Liver Meeting, bringing together scientists, clinicians, and associates from around the world to exchange information on the latest research, discuss new developments, and network with experts in the field of liver disease. 

The 75th Liver Meeting will be taking place from November 15 - 19, 2024 in San Diego, CA. 

Below is our team's contributions to The Liver Meeting 2024. 

Invited Presentations & Discussions

Justin Boike, MD, MPH  

  • MTE #13: Transjugular Intrahepatic Portosystemic Shunt in Acute-on-Chronic Liver Failure Patients: Why and When?  
    • Saturday November 16, 12:45 – 1:30PM 

Dempsey Hughes, MD  

  • Role of Nontraditional Modalities in Cardiovascular Risk Assessment Among Liver Transplant Candidates
    • MTE #4: Cardiovascular Risk Assessment in Liver Transplant Candidates 
    • Saturday November 16, 7:00 – 7:45AM  

Josh Levitsky, MD, MS  

  • Role of Noninvasive Biomarkers in the Diagnosis of Rejection Among Liver Transplant Recipients 
    • MTE #25: Balancing Act of Immunosuppression: Not Too Much, Not Too Little 
    • Sunday November 17, 12:45 – 1:30PM   

Laura Kulik, MD 

  • Debate: Should Hepatologists Administer Systemic Therapy? The Pro Position  
    • Postgraduate Course, Parts 1-4: The Future Is Here - Practicing Hepatology in 2024 (Session 2 – Liver Cancers)  
    • Friday November 15, 12:00 – 12:10PM  
  • Downstaging With Liver-Directed and Systemic Therapies 
    • Surgical Advances in Hepatocellular Carcinoma: Optimizing Patients for Resection and Transplant 
    • Saturday November 16, 8:00 – 8:15AM  
  • MTE #36: Managing Challenging Benign and Malignant Liver Lesions Before, During, and After Pregnancy   
    • Monday November 18, 12:45 – 1:30PM  

Moderators

Nabeel Wahid, MD – Transplant Hepatology Fellow  

  • The Best of the Liver Fellow Network 
    • Saturday November 16, 11:00AM – 12:30PM  
  • Career Development Workshop 
    • Sunday November 17, 8:00 – 9:30AM 

Parallel Abstract Presentations

The Liver Transplant Comorbidity Index (LTCI): A Composite Index of Ambulatory Pre-LT Factors to Identify Patients at Increased Risk of Post-LT Mortality 

  • Elizabeth Verna, Jennifer Lai, Michele Molinari, Amy Shui, Robert Rahimi, Daniela Ladner, Daniel Ganger, Matthew Kappus, Elizabeth King, Amit Tevar, Michael Volk, Andres Duarte-Rojo 

Effects of Timely Treatment on Outcomes of Larsucosterol for Severe Alcohol-associated Hepatitis (AHFIRM Trial) 

  • Lance Stein, Mitchell Shiffman, Aparna Goel, Allison Kwong, Ashwini Mehta, Christophe Moreno, Alexandre Louvet, Steven Flamm, Sanjaya Satapathy, Alexander Kuo, Daniel Ganger, Costica Aloman, Amanda Nicoll, Simone Strasser, Mack Mitchell, Srinivasan Dasarathy, Edmund Tse, Mark Thursz, Craig McClain, William Krebs, Deborah Scott, Christina Blevins, Julie Fergus, Norman Sussman, WeiQi Lin, Jim Brown 

X-box binding protein 1 (XBP1) transcriptionally regulates small heterodimer partner (SHP) expression in the liver. 

  • Xiaoying Liu, Alyssa Kriegermeier, Mahmoud Khalafalla, Brian LeCuyer, Andrew Benintende, Richard Green 

The competing role of hepatic X-box binding protein 1 (Xbp1) in bile acid metabolism and bile-acid induced injury in murine chronic cholestasis 

  • Alyssa Kriegermeier, Brian LeCuyer, Angela Hyon, Mahmoud Khalafalla, Xiaoying Liu, Richard Green 

Poster Abstract Presentations

A National Survey on the Perception and Approach to Frailty in Liver Transplantation 

  • Avesh Thuluvath, Adam Buckholz, Arpan Patel, Elizabeth Verna, Andres Duarte-Rojo 

The frailty component of hepatic encephalopathy - exploring physical and cognitive function in advanced chronic liver disease. 

  • Miguel Sogbe, Andres Duarte-Rojo, Randi Wong, Robert Rahimi, Pamela Bloomer, Alexandra Steinberg, Jennifer Lai 

ASSESSING LIVER TRANSPLANT REJECTION USING PAIRED BLOOD AND BIOPSY SAMPLES 

  • Josh Levitsky, Katelynn Madill-Thomsen, Jeff Reeve, Sunil Kurian, Philip Halloran 

Proteomic and Metabolomic Analysis from the CONFIRM Trial shows Biomarkers that Predict HRS Reversal without Vasoconstrictor Therapy 

  • Jasmohan Bajaj, Josh Levitsky, Andrew Allegreti, Pratima Sharma, Tianqi Ouyang, Scott Silvey, Khurram Jamil 

A Multi-Platform Approach Identifies Novel Candidate Biomarkers of Relapse in Autoimmune Hepatitis 

  • Claire Harrington, Swathi Krishnan, Scott Roberts, Paolo Cravedi, Marina Silveira, James Boyer, Yunshan Xu, Yunshan Xu, Katrina Peterson, Troy Fisher, Jack McGee, Michael Hollas, Michael Caldwell, Aniel Sanchez, Eleonora Forte, Neil Kelleher, David Assis, Josh Levitsky 

Utilizing Technology to Risk Stratify Patients with MASLD and Increase Rates of Identification of Clinically Significant Liver Fibrosis 

  • Rachel Orbuch, Justin Boike, Amanda Cheung 

Gender disparities in listing and transplantation in patients with ALD referred for early liver transplantation 

  • Katherine Cooper, Alessandro Colletta, Ami Patel, Kawthar Mohamed, Nicholas Lim, Weiyu Wu, Allison Kwong, Anjana Rajan, Amanda Cheung, Kaleb Tesfai, Veeral Ajmera, Kevin Wang, Hersh Shroff, Deepika Devuni 

Alcohol Use Disorder Treatment During Evaluation in Patients with ALD Referred for Early Liver Transplant 

  • Kevin Wang, Sasha Deutsch-Link, Weiyu Wu, Allison Kwong, Kawthar Mohamed, Nicholas Lim, Deepika Devuni, Katherine Cooper, Anjana Rajan, Amanda Cheung, Kaleb Tesfai, Veeral Ajmera, Hersh Shroff 

Prior Diagnosis of Decompensated Alcohol-Associated Liver Disease Does Not Increase Risk of Alcohol Relapse During Transplant Evaluation and May Increase Risk of Post-Transplant Alcohol Relapse 

  • Sasha Deutsch-Link, Kevin Wang, Weiyu Wu, Allison Kwong, Kawthar Mohamed, Nicholas Lim, Katherine Cooper, Deepika Devuni, Anjana Rajan, Amanda Cheung, Kaleb Tesfai, Veeral Ajmera, Hersh Shroff 

Predictors of survival and hepatic recompensation in patients with ALD referred for early liver transplantation 

  • Nicholas Lim, Giovanni Roldan, Kawthar Mohamed, Weiyu Wu, Gurpreet Judge, Katherine Cooper, Deepika Devuni, Kevin Wang, Hersh Shroff, Anjana Rajan, Amanda Cheung, Kaleb Tesfai, Veeral Ajmera, Allison Kwong 

Cardiometabolic Comorbidities are Associated with Lower Rates of Recompensation and Transplant Free Survival in Patients with Acute Alcohol Associated Liver Disease 

  • Kelly Torosian, Allison Kwong, Kaleb Tesfai, Katherine Cooper, Deepika Devuni, Kawthar Mohamed, Nicholas Lim, Weiyu Wu, Anjana Rajan, Amanda Cheung, Kevin Wang, Hersh Shroff, Veeral Ajmera 

Exploring the Role of Social Determinants in Early Liver Transplantation Relapse Rates and Outcomes: A Multicenter Analysis 

  • Anjana Rajan, Bima Hasjim, Nivetha Saravanan, Katherine Cooper, Deepika Devuni, Kawthar Mohamed, Nicholas Lim, Allison Kwong, Weiyu Wu, Kaleb Tesfai, Veeral Ajmera, Kevin Wang, Hersh Shroff, Amanda Cheung 

Cirrhotic Cardiomyopathy Independently Increases Post-Transplant Mortality in Patients Transplanted For Acute on Chronic Liver Failure: The MODEL Consortium Experience 

  • Thuraya Al-Sayegh, Justin Boike, George Cholankeril, Deepak Gupta, Gene Im, Prasun Kumar Jalal, Janice Jou, Constantine Karvellas, Saro Khemichian, Michael Kriss, Alexander Kuo, Ming Valerie Lin, Christina Lindenmeyer, Robert Rahimi, Kirti Shetty, Douglas Simonetto, Lance Stein, Ruben Hernaez, Don Rockey, Manhal Izzy 

The Echocardiographic Markers of Cirrhotic Cardiomyopathy Can Independently Predict Circulatory Failure and Posttransplant Death in Patients with Acute on Chronic Liver Failure: 15 Centers Experience 

  • Thuraya Al-Sayegh, Justin Boike, George Cholankeril, Deepak Gupta, Gene Im, Prasun Jalal, Janice Jou, Constantine Karvellas, Saro Khemichian, Michael Kriss, Alexander Kuo, Ming Valerie Lin, Christina Lindenmeyer, Robert Rahimi, Kirti Shetty, Douglas Simonetto, Lance Stein, Ruben Hernaez, Brett Fortune, Manhal Izzy 

Sleep Disturbance is Associated with Frailty, Impaired Physical Function, Fatigue, Anxiety, and Depression in Liver Transplant Recipients: Results from the LivCog Cohort Study 

  • Minjee Kim, Douglas Schaubel, Anna Gurian, Alexander Burdzy, Nianfu Song, Lindsay Berg, Lauren Cogar, Hannah Berman, Allison Novorita, Justin Boike, Michael Wolf, Sumeet Asrani, Julia Benavente, Marina Serper 

A Balancing Act: The Life-Saving Potential and Dilemma of Liver Transplantation as an Endpoint in Alcohol-Associated Hepatitis Trials 

  • Aparna Goel, Allison Kwong, Lance Stein, Alexandre Louvet, Sanjaya Satapathy, Ashwini Mehta, Steven Flamm, Costica Aloman, Julie Thompson, Amon Asgharpour, Daniel Ganger, Alexander Kuo, Fedja Rochling, Nikolaos Pyrsopoulos, Mitchell Shiffman, Christina Blevins, Julie Fergus, Deborah Scott, William Krebs, Jim Brown, Norman Sussman, WeiQi Lin 

Drinking Behavior in the AHFIRM trial as measured by Phosphatidyl Ethanol 

  • Steven Flamm, Mitchell Shiffman, Aparna Goel, Allison Kwong, Lance Stein, Ashwini Mehta, Christophe Moreno, Alexandre Louvet, Sanjaya Satapathy, Alexander Kuo, Daniel Ganger, Costica Aloman, Amanda Nicoll, Simone Strasser, Mack Mitchell, Srinivasan Dasarathy, Edmund Tse, Mark Thursz, Craig McClain, William Krebs, Deborah Scott, Christina Blevins, Julie Fergus, Jim Brown, Norman Sussman, WeiQi Lin, David Ellis 

Automated shear wave elastography captures MASLD onset in C57BL/6NTac mice preconditioned on a modified Amylin liver NASH diet 

  • Laura Griffin, Sri Radhakrishnan, Steven Yeung, Tomek Czernuszewicz, Christopher Moore, Juan Rojas, Brian Velasco, Paul Dayton 

EMERALD-Y90: a Phase 2 study to evaluate transarterial radioembolization (TARE) followed by durvalumab (D) and bevacizumab (B) for the treatment of participants (pts) with unresectable hepatocellular carcinoma (uHCC) eligible for embolization 

  • Laura Kulik, Riad Salem, Anne Noonan, Ben Spieler, Sarah White, Dex Underwood, Eric Heilbron, Binh Nguyen, Graham Wetherill, Renuka Iyer 

An ex-vivo approach to model metabolic dysfunction associated steatohepatitis (MASH) using patient-derived induced pluripotent stem cells. 

  • Ekta Minocha, Andrew Benintende, Ashwani Gupta, Nate Schmidt, John Purdy, Richard Green, Jason Wertheim 

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