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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Jensen TJ, Einfeldt MN, Liisberg K  et al.  Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jul 02;84(1):27-40. doi:10.1016/j.jacc.2024.04.022
  2. Jani VP, Strom JB, Gami A, Beussink-Nelson L, Patel R, Michos ED, Shah SJ, Freed BH, Mukherjee M  Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Am J Cardiol  2024 Jul 01;222:11-19. doi:10.1016/j.amjcard.2024.03.043
  3. Kitzman DW, Lewis GD, Pandey A, Borlaug BA, Sauer AJ, Litwin SE, Sharma K, Jorkasky DK, Khan S, Shah SJ  A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.  Eur J Heart Fail  2024 Jun 26;. doi:10.1002/ejhf.3305
  4. Verma S, Butler J, Borlaug BA, Davies M, Kitzman DW, Shah SJ, Petrie MC, Barros E, Rönnbäck C, Vestergaard LS  et al.  Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials.  J Am Coll Cardiol  2024 Jun 19;. pii:S0735-1097(24)07445-X
  5. Gustafsson F, Petrie MC, Komtebedde J, Swarup V, Winkler S, Hasenfuß G, Borlaug BA, Mohan RC, Flaherty JD, Sverdlov AL  et al.  2-Year Outcomes of an Atrial Shunt Device in HFpEF/HFmrEF: Results From REDUCE LAP-HF II.  JACC Heart Fail  2024 Jun 13;. pii:S2213-1779(24)00331-7
  6. Schou M, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jun 12;. pii:S0735-1097(24)07126-2
  7. Simon GE, Moise N, Mohr DC  Management of Depression in Adults: A Review.  JAMA  2024 Jun 10;. doi:10.1001/jama.2024.5756
  8. Kondo T, Campbell R, Jhund PS, Anand IS, Carson PE, Lam CSP, Shah SJ, Vaduganathan M, Zannad F, Zile MR  et al.  Low Natriuretic Peptide Levels and Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.  JACC Heart Fail  2024 Jun 06;. pii:S2213-1779(24)00414-1
  9. Edmonston D, Lydon E, Mulder H, Chiswell K, Lampron Z, Marsolo K, Goss A, Ayoub I, Shah RC, Chang AR  et al.  Concordance With Screening and Treatment Guidelines for Chronic Kidney Disease in Type 2 Diabetes.  JAMA Netw Open  2024 Jun 03;7(6):e2418808. doi:10.1001/jamanetworkopen.2024.18808
  10. Marrero N, Jha K, Razavi AC, Boakye E, Anchouche K, Dzaye O, Budoff MJ, Tsai MY, Shah SJ, Rotter JI  et al.  Identifying People at High Risk for Severe Aortic Stenosis: Aortic Valve Calcium Versus Lipoprotein(a) and Low-Density Lipoprotein Cholesterol.  Circ Cardiovasc Imaging  2024 Jun;17(6):e016372. doi:10.1161/CIRCIMAGING.123.016372
  11. Filipp M, Shah SJ  Proving SGLT2 Inhibitor-Mediated Improvement in Cardiomyocyte Energetics: Beyond a Reasonable Doubt?  Circ Heart Fail  2024 Jun;17(6):e011646. doi:10.1161/CIRCHEARTFAILURE.124.011646
  12. Vaduganathan M, Claggett BL, Lam CSP, Pitt B, Senni M, Shah SJ, Voors AA, Zannad F, Desai AS, Jhund PS  et al.  Finerenone in patients with heart failure with mildly reduced or preserved ejection fraction: Rationale and design of the FINEARTS-HF trial.  Eur J Heart Fail  2024 Jun;26(6):1324-1333. doi:10.1002/ejhf.3253
  13. Solomon SD, Ostrominski JW, Vaduganathan M, Claggett B, Jhund PS, Desai AS, Lam CSP, Pitt B, Senni M, Shah SJ  et al.  Baseline characteristics of patients with heart failure with mildly reduced or preserved ejection fraction: The FINEARTS-HF trial.  Eur J Heart Fail  2024 Jun;26(6):1334-1346. doi:10.1002/ejhf.3266
  14. Wang X, Yue F  Hijacked enhancer-promoter and silencer-promoter loops in cancer.  Curr Opin Genet Dev  2024 Jun;86:102199. doi:10.1016/j.gde.2024.102199
  15. Pabón MA, Wang X, Lam CSP, O'Meara E, Vaduganathan M, Claggett BL, Foà A, Lu H, Langkilde AM, De Boer RA  et al.  Sex Differences in Heart Failure With Improved Ejection Fraction: The DELIVER Trial.  JACC Heart Fail  2024 Jun;12(6):1119-1122. doi:10.1016/j.jchf.2024.03.011
  16. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB  et al.  Targeted Metabolomic Profiling of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The PRESERVED-HF Trial.  JACC Heart Fail  2024 Jun;12(6):999-1011. doi:10.1016/j.jchf.2024.02.018
  17. Patel RB, Silvestry FE, Komtebedde J, Solomon SD, Hasenfuß G, Litwin SE, Borlaug BA, Price MJ, Kawash R, Hummel SL  et al.  Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.  JAMA Cardiol  2024 Jun 01;9(6):507-522. doi:10.1001/jamacardio.2024.0520
  18. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  19. Belue MJ, Harmon SA, Yang D, An JY, Gaur S, Law YM, Turkbey E, Xu Z, Tetreault J, Lay NS  et al.  Deep Learning-Based Detection and Classification of Bone Lesions on Staging Computed Tomography in Prostate Cancer: A Development Study.  Acad Radiol  2024 Jun;31(6):2424-2433. doi:10.1016/j.acra.2024.01.009
  20. Castaño A, Heitner SB, Masri A, Huda A, Calambur V, Bruno M, Schumacher J, Emir B, Isherwood C, Shah SJ  EstimATTR: A Simplified, Machine-Learning-Based Tool to Predict the Risk of Wild-Type Transthyretin Amyloid Cardiomyopathy.  J Card Fail  2024 Jun;30(6):778-787. doi:10.1016/j.cardfail.2023.11.017
  21. Mihaljevic JR, Chief C, Malik M, Oshinubi K, Doerry E, Gel E, Hepp C, Lant T, Mehrotra S, Sabo S  An inaugural forum on epidemiological modeling for public health stakeholders in Arizona.  Front Public Health  2024;12:1357908. pii:1357908
  22. Ye J, Woods D, Jordan N, Starren J  The role of artificial intelligence for the application of integrating electronic health records and patient-generated data in clinical decision support.  AMIA Jt Summits Transl Sci Proc  2024;2024:459-467
  23. Ladner DP, Manski CF, Mehrotra S  New Liver Allocation Policy and National Liver Transplant Volume.  JAMA Surg  2024 May 29;. doi:10.1001/jamasurg.2024.1209
  24. Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA  et al.  Pediatric Gastrointestinal Outcomes During the Post-Acute Phase of COVID-19.  medRxiv  2024 May 22;. pii:2024.05.21.24307699
  25. Lassen MCH, Ostrominski JW, Inzucchi SE, Claggett BL, Kulac I, Jhund P, de Boer RA, Hernandez AF, Kosiborod MN, Lam CSP  et al.  Effect of dapagliflozin in patients with diabetes and heart failure with mildly reduced or preserved ejection fraction according to background glucose-lowering therapy: A pre-specified analysis of the DELIVER trial.  Eur J Heart Fail  2024 May 15;. doi:10.1002/ejhf.3269
  26. Shah SJ, Sharma K, Borlaug BA, Butler J, Davies M, Kitzman DW, Petrie MC, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and Diuretic Use in Obesity-Related Heart Failure with Preserved Ejection Fraction: A Pooled Analysis of the STEP-HFpEF and STEP-HFpEF-DM trials.  Eur Heart J  2024 May 13;. pii:ehae322
  27. Ostrominski JW, Aggarwal R, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Lam CSP, Pitt B, Senni M, Shah SJ  et al.  Generalizability of the Spectrum of Kidney Risk in the FINEARTS-HF Trial to U.S. Adults With Heart Failure.  J Card Fail  2024 May 11;. pii:S1071-9164(24)00156-8
  28. Ashworth RC, Malone JR, Franklin D, Sorce LR, Clayman ML, Frader J, White DB, Michelson KN  Associations of Patient and Parent Characteristics With Parental Decision Regret in the PICU: A Secondary Analysis of the 2015-2017 Navigate Randomized Comparative Trial.  Pediatr Crit Care Med  2024 May 10;. doi:10.1097/PCC.0000000000003534
  29. Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Beussink-Nelson L, Shah SJ  et al.  Mitochondria regulate proliferation in adult cardiac myocytes.  J Clin Invest  2024 May 09;. pii:e165482
  30. Mukherjee M, Strom JB, Afilalo J, Hu M, Beussink-Nelson L, Kim J, Addetia K, Bertoni AG, Gottdiener JS, Michos ED  et al.  Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Circ Cardiovasc Imaging  2024 May;17(5):e016420. doi:10.1161/CIRCIMAGING.123.016420
  31. Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ  et al.  Favorable Antiviral Effect of Metformin on Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of Coronavirus Disease 2019.  Clin Infect Dis  2024 May 01;. pii:ciae159
  32. Kiraly AP, Cunningham CA, Najafi R, Nabulsi Z, Yang J, Lau C, Ledsam JR, Ye W, Ardila D, McKinney SM  et al.  Assistive AI in Lung Cancer Screening: A Retrospective Multinational Study in the United States and Japan.  Radiol Artif Intell  2024 May;6(3):e230079. pii:e230079
  33. Yaku H, Fudim M, Shah SJ  Role of splanchnic circulation in the pathogenesis of heart failure: State-of-the-art review.  J Cardiol  2024 May;83(5):330-337. doi:10.1016/j.jjcc.2024.02.004
  34. Lakhtakia T, Smith SR, Mohr DC, Stamatis CA  Longitudinal associations of daily affective dynamics with depression, generalized anxiety, and social anxiety symptoms.  J Affect Disord  2024 May 01;352:437-444. doi:10.1016/j.jad.2024.01.250
  35. Maning J, Shah SJ, Patel RB  With Great Data Come Great Responsibilities: The Cardiac Amyloidosis Registry Study.  J Card Fail  2024 May;30(5):679-681. doi:10.1016/j.cardfail.2023.12.016
  36. Shi Y, Lenze EJ, Mohr DC, Lee JM, Hu L, Metts CL, Fong MWM, Wong AWK  Post-stroke Depressive Symptoms and Cognitive Performances: A Network Analysis.  Arch Phys Med Rehabil  2024 May;105(5):892-900. doi:10.1016/j.apmr.2023.10.006
  37. Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrøm SZ, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Verma S  et al.  Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials.  Lancet  2024 Apr 27;403(10437):1635-1648. doi:10.1016/S0140-6736(24)00469-0
  38. Smith JD, Carroll AJ, Sanuade OA, Johnson R, Abramsohn EM, Abbas H, Ahmad FS, Eggleston A, Lazar D, Lindau ST  et al.  Process of Engaging Community and Scientific Partners in the Development of the CIRCL-Chicago Study Protocol.  Ethn Dis  2023 Dec;DECIPHeR(Spec Issue):18-26. doi:10.18865/ed.DECIPHeR.18
  39. Adler DA, Stamatis CA, Meyerhoff J, Mohr DC, Wang F, Aranovich GJ, Sen S, Choudhury T  Measuring algorithmic bias to analyze the reliability of AI tools that predict depression risk using smartphone sensed-behavioral data.  Npj Ment Health Res  2024 Apr 22;3(1):17. pii:17
  40. Kosiborod MN, Petrie MC, Borlaug BA, Butler J, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Treppendahl MB, Verma S  et al.  Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes.  N Engl J Med  2024 Apr 18;390(15):1394-1407. doi:10.1056/NEJMoa2313917
  41. Strom JB, Mukherjee M, Beussink-Nelson L, Gardin JM, Freed BH, Shah SJ, Afilalo J  Reference Values for Indexed Echocardiographic Chamber Sizes in Older Adults: The Multi-Ethnic Study of Atherosclerosis.  J Am Heart Assoc  2024 Apr 16;13(8):e034029. doi:10.1161/JAHA.123.034029
  42. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Apr 02;. doi:10.1007/s00392-024-02433-2
  43. Chiu L, Agrawal V, Armstrong D, Brittain E, Collins S, Hemnes AR, Hill JA, Lindenfeld J, Shah SJ, Stevenson LW  et al.  Correlates of Plasma NT-proBNP/Cyclic GMP Ratio in Heart Failure With Preserved Ejection Fraction: An Analysis of the RELAX Trial.  J Am Heart Assoc  2024 Apr 02;13(7):e031796. pii:e031796
  44. Peikert A, Vaduganathan M, Claggett BL, Kulac IJ, Foà A, Desai AS, Jhund PS, Carberry J, Lam CSP, Kosiborod MN  et al.  Dapagliflozin in patients with heart failure and previous myocardial infarction: A participant-level pooled analysis of DAPA-HF and DELIVER.  Eur J Heart Fail  2024 Apr;26(4):912-924. doi:10.1002/ejhf.3184
  45. Jonathan GK, Abitante G, McBride A, Bernstein-Sandler M, Babington P, Dopke CA, Rossom RC, Mohr DC, Goulding EH  LiveWell, a smartphone-based self-management intervention for bipolar disorder: Intervention participation and usability analysis.  J Affect Disord  2024 Apr 01;350:926-936. doi:10.1016/j.jad.2024.01.099
  46. Huang J, Galal G, Mukhin V, Etemadi M, Tanna AP  Prediction and Detection of Glaucomatous Visual Field Progression Using Deep Learning on Macular Optical Coherence Tomography.  J Glaucoma  2024 Apr 01;33(4):246-253. doi:10.1097/IJG.0000000000002359
  47. Hitsman B, Papandonatos GD, Fox EN, Bauer AM, Gollan JK, Huffman MD, Mohr DC, Leone FT, Khan SS, Achenbach CJ  et al.  Effect of early medication adherence on behavioral treatment utilization and smoking cessation among individuals with current or past major depressive disorder.  Addict Behav  2024 Apr;151:107952. doi:10.1016/j.addbeh.2024.107952
  48. Peikert A, Bart BA, Vaduganathan M, Claggett BL, Kulac IJ, Kosiborod MN, Desai AS, Jhund PS, Lam CSP, Inzucchi SE  et al.  Contemporary Use and Implications of Beta-Blockers in Patients With HFmrEF or HFpEF: The DELIVER Trial.  JACC Heart Fail  2024 Apr;12(4):631-644. doi:10.1016/j.jchf.2023.09.007
  49. Kim M, Wang P, Clow PA, Chien IE, Wang X, Peng J, Chai H, Liu X, Lee B, Ngan CY  et al.  Multifaceted roles of cohesin in regulating transcriptional loops.  bioRxiv  2024 Mar 27;. pii:2024.03.25.586715
  50. Anibal JT, Landa AJ, Hang NTT, Song MJ, Peltekian AK, Shin A, Huth HB, Hazen LA, Christou AS, Rivera J  et al.  Omicron detection with large language models and YouTube audio data.  medRxiv  2024 Mar 27;. pii:2022.09.13.22279673