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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM  et al.  Triaging mammography with artificial intelligence: an implementation study.  Breast Cancer Res Treat  2025 May;211(1):1-10. doi:10.1007/s10549-025-07616-7
  2. Yu JK, Gauen AM, Zmora R, Petito LC, Kho AN, Smith SM, Allen NB  Patient Predictors of Combination Therapy as Initial Hypertension Treatment: The AOURP (All of Us Research Program) Registry.  J Am Heart Assoc  2025 Mar 26;:e037626. doi:10.1161/JAHA.124.037626
  3. Wang A, French D, Black B, Kho AN  Cohort study examining social determinants of health and their association with mortality among hospitalised adults in New York and California.  BMJ Public Health  2025 Jan;3(1):e001266. pii:e001266
  4. Eduardo MB, Cottone G, McCloskey CW, Liu S, Palma FR, Zappia MP, Islam ABMMK, Gao P, Setya J, Dennis S  et al.  A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells.  Sci Adv  2025 Mar 21;11(12):eads9182. pii:eads9182
  5. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung W, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic Method for Classifying Multiple Congenital Anomaly Cases in Electronic Health Records.  Genet Med  2025 Mar 18;:101415. doi:10.1016/j.gim.2025.101415
  6. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Mar 17;:101097JU0000000000004498. doi:10.1097/JU.0000000000004498
  7. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Mar 17;:e70024. doi:10.1111/nmo.70024
  8. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Mar 17;. doi:10.1161/HYPERTENSIONAHA.124.22349
  9. Wang Q, Wang J, Mathur R, Youngblood MW, Jin Q, Hou Y, Stasiak LA, Luan Y, Zhao H, Hilz S  et al.  Spatial 3D genome organization reveals intratumor heterogeneity in primary glioblastoma samples.  Sci Adv  2025 Mar 14;11(11):eadn2830. pii:eadn2830
  10. Knapp AA, Cohen K, Kruzan KP, Kornfield R, Herrera M, Pederson AB, Lee S, Macapagal K, Roulston CA, Clarke K  et al.  Teen Perspectives on Integrating Digital Mental Health Programs for Teens Into Public Libraries ("I Was Always at the Library"): Qualitative Interview Study.  JMIR Form Res  2025 Mar 13;9:e67454. doi:10.2196/67454
  11. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar 13;. doi:10.1007/s00134-025-07848-7
  12. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 12;. pii:e250103
  13. Filipp M, Ge ZD, DeBerge M, Lantz C, Glinton K, Gao P, Smolgovsky S, Dai J, Zhao YY, Yvan-Charvet L  et al.  Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.  Circulation  2025 Mar 12;. doi:10.1161/CIRCULATIONAHA.124.070248
  14. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in a US Cohort: The MESA.  Hypertension  2025 Mar 07;. doi:10.1161/HYPERTENSIONAHA.124.23970
  15. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Mar 05;. pii:e250025
  16. Eisinger-Mathason TSK, Leshin J, Lahoti V, Fridsma DB, Mucaj V, Kho AN  Data linkage multiplies research insights across diverse healthcare sectors.  Commun Med (Lond)  2025 Mar 04;5(1):58. pii:58
  17. Kanwar K, Ramachandran R, Stein JD, Andrews CA, Chaudhury AS, Ige M, Zhou X, Marwah S, Li Y, Evans CT  et al.  The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma.  Transl Vis Sci Technol  2025 Mar 03;14(3):15. pii:15
  18. Shah SJ, Bonderman D, Borlaug BA, Cleland JGF, Lack G, Lu W, Voors AA, Zannad F, Gladwin MT  Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study.  Circ Heart Fail  2025 Mar;18(3):e011381. doi:10.1161/CIRCHEARTFAILURE.123.011381
  19. Gundogdu B, Chatterjee A, Medved M, Bagci U, Karczmar GS, Oto A  Physics-Informed Autoencoder for Prostate Tissue Microstructure Profiling with Hybrid Multidimensional MRI.  Radiol Artif Intell  2025 Mar;7(2):e240167. pii:e240167
  20. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S  et al.  Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial.  Lancet Diabetes Endocrinol  2025 Mar;13(3):196-209. doi:10.1016/S2213-8587(24)00304-8
  21. Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H  NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High-Resolution Short-Echo-Time MR Spectroscopy Datasets.  Radiol Artif Intell  2025 Mar;7(2):e230579. pii:e230579
  22. Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C  et al.  Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 01;10(3):284-289. doi:10.1001/jamacardio.2024.4417
  23. Jain K, Katz R, Isakova T, Kizer JR, Sharma S, Psaty BM, Shah SJ, Ix J, Mehta R  Association of Fibroblast Growth Factor 23 and Cardiac Mechanics in the Cardiovascular Health Study.  Kidney360  2025 Mar 01;6(3):391-399. doi:10.34067/KID.0000000643
  24. Ostrominski JW, Claggett BL, Miao ZM, Filippatos G, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Viswanathan P  et al.  Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease.  Diabetes Care  2025 Feb 28;. pii:dc241873
  25. Kruzan KP, Washburn JJ, Aaby D, Nguyen T, Mohr DC  Subgroups of non-suicidal self-injury in a large diverse sample of online help-seekers.  Front Psychiatry  2025;16:1513685. pii:1513685
  26. Goreish MH, Gennaro N, Perronne L, Durak G, Borhani AA, Savas H, Kelahan L, Avery R, Subedi K, Agirlar Trabzonlu T  et al.  Paradoxical Response to Neoadjuvant Therapy in Undifferentiated Pleomorphic Sarcoma: Increased Tumor Size on MRI Associated with Favorable Pathology.  Cancers (Basel)  2025 Feb 27;17(5). pii:830
  27. Meyerhoff J, Popowski SA, Lakhtakia T, Tack E, Kornfield R, Kruzan KP, Krause CJ, Nguyen T, Rushton K, Pisani AR  et al.  Automated Digital Safety Planning Interventions for Young Adults: Qualitative Study Using Online Co-design Methods.  JMIR Form Res  2025 Feb 26;9:e69602. pii:e69602
  28. Chen C, Nishtala A, Li E, Schultz WM, Baldridge AS, Groenendyk JW, Lee DC, Shah SJ, Burt RK, Freed BH  The effect of hematopoietic stem cell transplantation on cardiac mechanics in systemic sclerosis.  Int J Cardiovasc Imaging  2025 Feb 26;. doi:10.1007/s10554-025-03365-2
  29. Gennaro N, Soliman M, Borhani AA, Kelahan L, Savas H, Avery R, Subedi K, Trabzonlu TA, Krumpelman C, Yaghmai V  et al.  Delta Radiomics and Tumor Size: A New Predictive Radiomics Model for Chemotherapy Response in Liver Metastases from Breast and Colorectal Cancer.  Tomography  2025 Feb 20;11(3). pii:20
  30. Inciardi RM, Lu H, Claggett BL, Desai AS, Jhund PS, Lam CSP, Kosiborod MN, Inzucchi SE, Martinez FA, de Boer RA  et al.  Severe Heart Failure and Treatment With Dapagliflozin Across the Ejection Fraction Spectrum: DAPA-HF and DELIVER.  JACC Heart Fail  2025 Feb 20;. pii:S2213-1779(25)00080-0
  31. Gustafson AA, Trinh KV, Lomasney JW, Shah SJ, Hinchcliff ME  Acute Systemic Sclerosis-Associated Cardiomyopathy That Improved With Glucocorticoids and Cyclophosphamide.  JACC Case Rep  2025 Feb 19;30(4):102948. pii:102948
  32. Quiriarte H, Cho E, Kim Y, Doiron JE, Davis G, Stampley J, Noland RC, Li Z, Shah SJ, Irving BA  et al.  Impact of Voluntary Exercise on Systemic Inflammation in a 2? Hit Model of Heart Failure With Preserved Ejection Fraction.  J Am Heart Assoc  2025 Feb 18;14(4):e038789. doi:10.1161/JAHA.124.038789
  33. Luo Y, Li Y, Ogunyemi O, Koski E, Himes BE  Leveraging large language models for academic conference organization.  NPJ Digit Med  2025 Feb 14;8(1):101. pii:101
  34. Mohammadi M, Hasjim BJ, Balbale SN, Polineni P, Huang AA, Paukner M, Banea T, Dentici O, Vitello DJ, Obayemi JE  et al.  Disease trajectory and competing risks of patients with cirrhosis in the US.  PLoS One  2025;20(2):e0313152. pii:e0313152
  35. Braumann S, Macherey-Meyer S, Polzin A, Costard-Jäckle A, Morbach C, Haring B, Lapp H, Ten Cate V, Gieswinkel A, Weliwitage J  et al.  MYSTERY-HF - Myeloperoxidase Inhibition in Patients With Heart Failure and Reduced Ejection Fraction - a Phase II Randomized Controlled Trial.  Circulation  2025 Feb 12;. doi:10.1161/CIRCULATIONAHA.125.074085
  36. Zhou X, Zhou J, Wang C, Xie Q, Ding K, Mao C, Liu Y, Cao Z, Chu H, Chen X  et al.  PH-LLM: Public Health Large Language Models for Infoveillance.  medRxiv  2025 Feb 10;. pii:2025.02.08.25321587
  37. Raeisi Dehkordi S, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U  et al.  Breakage fusion bridge cycles drive high oncogene number with moderate intratumoural heterogeneity.  Nat Commun  2025 Feb 10;16(1):1497. pii:1497
  38. Lyu H, Chen X, Cheng Y, Zhang T, Wang P, Wong JH, Wang J, Stasiak L, Sun L, Yang G  et al.  Pioneer factor GATA6 promotes colorectal cancer through 3D genome regulation.  Sci Adv  2025 Feb 07;11(6):eads4985. pii:eads4985
  39. Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N  et al.  Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.  Science  2025 Feb 07;387(6734):eadp4753. doi:10.1126/science.adp4753
  40. Culler K, Zelnick LR, Mehta RC, de Sosa GR, Kansal M, Rao PS, Bhat Z, Taliercio J, Horwitz E, Chen J  et al.  The ICAM1 p.K56M variant and risk of heart failure in chronic kidney disease: the Chronic Renal Insufficiency Cohort study.  Heart  2025 Feb 06;. pii:heartjnl-2024-325205
  41. Jakubek YA, Ma X, Stilp AM, Yu F, Bacon J, Wong JW, Aguet F, Ardlie K, Arnett DK, Barnes K  et al.  Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.  Am J Hum Genet  2025 Feb 06;112(2):276-290. doi:10.1016/j.ajhg.2024.12.014
  42. Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA  et al.  Pediatric Gastrointestinal Tract Outcomes During the Postacute Phase of COVID-19.  JAMA Netw Open  2025 Feb 03;8(2):e2458366. pii:e2458366
  43. Adli M, Przybyla L, Burdett T, Burridge PW, Cacheiro P, Chang HY, Engreitz JM, Gilbert LA, Greenleaf WJ, Hsu L  et al.  MorPhiC Consortium: towards functional characterization of all human genes.  Nature  2025 Feb;638(8050):351-359. doi:10.1038/s41586-024-08243-w
  44. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Viswanathan P, Kolkhof P, Schloemer P, Amarante F, Lam CSP  et al.  Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial.  Lancet Diabetes Endocrinol  2025 Feb;13(2):107-118. doi:10.1016/S2213-8587(24)00309-7
  45. Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN  Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care.  Contemp Clin Trials Commun  2025 Feb;43:101413. pii:101413
  46. Cai W, Liu X, Barajas S, Xiao S, Vemula S, Chen H, Yang Y, Bochers C, Henley D, Liu S  et al.  Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes.  Leukemia  2025 Feb;39(2):296-307. doi:10.1038/s41375-024-02462-w
  47. Shah SJ, Rigolli M, Javidialsaadi A, Patel RB, Khadra S, Goyal P, Little S, Wever-Pinzon O, Owens AT, Skali H  et al.  Cardiac Myosin Inhibition in Heart Failure With Normal and Supranormal Ejection Fraction: Primary Results of the EMBARK-HFpEF Trial.  JAMA Cardiol  2025 Feb 01;10(2):170-175. doi:10.1001/jamacardio.2024.3810
  48. Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B  et al.  Estimated Long-Term Benefits of Finerenone in Heart Failure: A Prespecified Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Feb 01;10(2):176-181. doi:10.1001/jamacardio.2024.3782
  49. Peterson TE, Lima JAC, Shah SJ, Bluemke DA, Bertoni AG, Liu Y, Ngo D, Varadarajan V, Mychaleckyj JC, Johnson CW  et al.  Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis.  ESC Heart Fail  2025 Feb;12(1):239-249. doi:10.1002/ehf2.15073
  50. Koh J, Caron S, Watters AN, Vaidyanathan M, Melnick D, Santi A, Hudson K, Arguelles C, Mathur P, Etemadi M  Technological Adjuncts to Streamline Patient Recruitment, Informed Consent, and Data Management Processes in Clinical Research: Observational Study.  JMIR Form Res  2025 Jan 29;9:e58628. pii:e58628