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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN  Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care.  Contemp Clin Trials Commun  2025 Feb;43:101413. pii:101413
  2. Gerratana L, Davis AA, Foffano L, Reduzzi C, Rossi T, Medford A, Clifton K, Shah AN, Bucheit L, Velimirovic M  et al.  Integrating machine learning-predicted circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in metastatic breast cancer: A proof of principle study on endocrine resistance profiling.  Cancer Lett  2025 Jan 28;609:217325. doi:10.1016/j.canlet.2024.217325
  3. Butt JH, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Viswanathan P, Lage A, Scheerer MF, Lam CSP  et al.  Finerenone, Obesity, and Heart Failure With Mildly Reduced/Preserved Ejection Fraction: Prespecified Analysis of FINEARTS-HF.  J Am Coll Cardiol  2025 Jan 21;85(2):140-155. doi:10.1016/j.jacc.2024.10.111
  4. Yang M, Henderson AD, Talebi A, Atherton JJ, Chiang CE, Chopra V, Comin-Colet J, Kosiborod MN, Kerr Saraiva JF, Claggett BL  et al.  Effect of Finerenone on the KCCQ in Patients With HFmrEF/HFpEF: A Prespecified Analysis of FINEARTS-HF.  J Am Coll Cardiol  2025 Jan 21;85(2):120-136. doi:10.1016/j.jacc.2024.09.023
  5. Mc Causland FR, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Brinker M, Perkins R, Scheerer MF  et al.  Finerenone and Kidney Outcomes in Patients With Heart Failure: The FINEARTS-HF Trial.  J Am Coll Cardiol  2025 Jan 21;85(2):159-168. doi:10.1016/j.jacc.2024.10.091
  6. Desai AS, Vaduganathan M, Claggett BL, Kulac IJ, Jhund PS, Cunningham J, Borentain M, Lay-Flurrie J, Viswanathan P, Rohwedder K  et al.  Finerenone in Patients With a Recent Worsening Heart Failure Event: The FINEARTS-HF Trial.  J Am Coll Cardiol  2025 Jan 21;85(2):106-116. doi:10.1016/j.jacc.2024.09.004
  7. Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B  et al.  Time to Significant Benefit of Finerenone in Patients With Heart Failure.  J Am Coll Cardiol  2025 Jan 21;85(2):199-202. doi:10.1016/j.jacc.2024.09.018
  8. Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H  NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High- Resolution Short Echo Time MR Spectroscopy Datasets.  Radiol Artif Intell  2025 Jan 15;:e230579. doi:10.1148/ryai.230579
  9. Vaduganathan M, Claggett BL, Kulac IJ, Miao ZM, Desai AS, Jhund PS, Henderson AD, Brinker M, Lay-Flurrie J, Viswanathan P  et al.  Effects of the Nonsteroidal MRA Finerenone With and Without Concomitant SGLT2 Inhibitor Use in Heart Failure.  Circulation  2025 Jan 14;151(2):149-158. doi:10.1161/CIRCULATIONAHA.124.072055
  10. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Viswanathan P, Kolkhof P, Schloemer P, Amarante F, Lam CSP  et al.  Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial.  Lancet Diabetes Endocrinol  2025 Jan 13;. pii:S2213-8587(24)00309-7
  11. Lei Y, Li Z, Bui Q, DePaul O, Nicol GE, Mohr DC, Fong MWM, Metts CL, Lee SI, Tomazin SE  et al.  Satisfaction, user experiences, and initial efficacy of a technology-supported self-management intervention (iSMART) to improve post-stroke functioning: a remoted randomized controlled trial.  Top Stroke Rehabil  2025 Jan 10;:1-15. doi:10.1080/10749357.2025.2450950
  12. Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ  Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma.  PLoS One  2025;20(1):e0312415. pii:e0312415
  13. Docherty KF, Henderson AD, Jhund PS, Claggett BL, Desai AS, Mueller K, Viswanathan P, Scalise A, Lam CSP, Senni M  et al.  Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial.  Circulation  2025 Jan 07;151(1):45-58. doi:10.1161/CIRCULATIONAHA.124.072011
  14. Jakubek YA, Ma X, Stilp AM, Yu F, Bacon J, Wong JW, Aguet F, Ardlie K, Arnett DK, Barnes K  et al.  Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.  Am J Hum Genet  2025 Jan 06;. pii:S0002-9297(24)00456-7
  15. Swaroop A, Yue F  Chromatin hubs drive key regulatory networks in leukemia.  Mol Cell  2025 Jan 02;85(1):1-2. doi:10.1016/j.molcel.2024.12.011
  16. Stiles-Shields C, Reyes KM, Lakhtakia T, Smith SR, Barnas OE, Gray EL, Krause CJ, Kruzan KP, Kwasny MJ, Mir Z  et al.  Correction: A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial.  BMC Psychiatry  2025 Jan 02;25(1):4. pii:4
  17. Ragon B, Seymour A, Whipple EC, Surkis A, Haberstroh A, Muilenburg J, Rethlefsen ML, Aspinall EE, Deaver J, Dexter N  et al.  The role of information science within the clinical translational science ecosystem.  J Clin Transl Sci  2025;8(1):e224. pii:e224
  18. Vardeny O, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.  JAMA Cardiol  2025 Jan 01;10(1):42-48. pii:e244539
  19. Nargesi AA, Adejumo P, Dhingra LS, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN  et al.  Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing.  JACC Heart Fail  2025 Jan;13(1):75-87. doi:10.1016/j.jchf.2024.08.012
  20. Sadeghpour A, Jiang Z, Hummel YM, Frost M, Lam CSP, Shah SJ, Lund LH, Stone GW, Swaminathan M, Weissman NJ  et al.  An Automated Machine Learning-Based Quantitative Multiparametric Approach for Mitral Regurgitation Severity Grading.  JACC Cardiovasc Imaging  2025 Jan;18(1):1-12. doi:10.1016/j.jcmg.2024.06.011
  21. Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y  et al.  Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.  Hypertension  2025 Jan;82(1):36-45. doi:10.1161/HYPERTENSIONAHA.124.22095
  22. Naved BA, Luo Y  Contrasting rule and machine learning based digital self triage systems in the USA.  NPJ Digit Med  2024 Dec 27;7(1):381. pii:381
  23. Gould A, Luan Y, Hou Y, Korobova FV, Chen L, Arrieta VA, Amidei C, Ward R, Gomez C, Castro B  et al.  Endothelial Response to Blood-Brain Barrier Disruption in the Human Brain.  JCI Insight  2024 Dec 26;. pii:e187328
  24. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2024 Dec 24;. doi:10.1002/ehf2.15184
  25. Seyithanoglu D, Durak G, Keles E, Medetalibeyoglu A, Hong Z, Zhang Z, Taktak YB, Cebeci T, Tiwari P, Velichko YS  et al.  Advances for Managing Pancreatic Cystic Lesions: Integrating Imaging and AI Innovations.  Cancers (Basel)  2024 Dec 22;16(24). pii:4268
  26. Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP  et al.  Interleukin 8-CXCR2 mediated neutrophil extracellular trap (NET) formation in biliary atresia associated with NET-Induced stellate cell activation.  Hepatology  2024 Dec 18;. doi:10.1097/HEP.0000000000001195
  27. Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C  et al.  Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.  JAMA Cardiol  2024 Dec 18;. doi:10.1001/jamacardio.2024.4417
  28. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  Res Sq  2024 Dec 16;. pii:rs.3.rs-5487737
  29. Shin J, Luo Y  Relationship between exposure to multiple heavy metals and depressive symptoms in the US: The impact of alcohol consumption.  Heliyon  2024 Dec 15;10(23):e40221. pii:e40221
  30. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2024 Dec 11;. doi:10.1007/s11606-024-09159-x
  31. Stefanopoulos L, Kim BW, Sheppard J, Azcona EA, Vike NL, Bari S, Lalvani S, Woodward S, Maglaveras N, Block M  et al.  Discrete, recurrent, and scalable patterns in non-operant judgement underlie affective picture ratings.  Cogn Process  2024 Dec 07;. doi:10.1007/s10339-024-01250-9
  32. Quiriarte H, Noland RC, Stampley JE, Davis G, Li Z, Cho E, Kim Y, Doiron J, Spielmann G, Ghosh S  et al.  Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF.  JACC Basic Transl Sci  2024 Dec;9(12):1409-1425. doi:10.1016/j.jacbts.2024.07.009
  33. Wang MC, Awoyemi T, Allen NB, Shah R, Nayor M, Luo Y, Lima JAC, Lloyd-Jones DM, Khan SS  Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study.  Am J Prev Cardiol  2024 Dec;20:100889. pii:100889
  34. Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J  et al.  Author Correction: Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes.  Nat Med  2024 Dec;30(12):3778. doi:10.1038/s41591-024-03372-1
  35. Fudim M, Borlaug BA, Mohan RC, Price MJ, Fail P, Goyal P, Hummel SL, Zirakashvili T, Shaburishvili T, Patel RB  et al.  Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial.  JAMA Cardiol  2024 Dec 01;9(12):1143-1153. doi:10.1001/jamacardio.2024.2612
  36. Haynes G, Muhammad F, Weber KA, Khan AF, Hameed S, Shakir H, Van Hal M, Dickson D, Rohan M, Dhaher Y  et al.  Tract-specific magnetization transfer ratio provides insights into the severity of degenerative cervical myelopathy.  Spinal Cord  2024 Dec;62(12):700-707. doi:10.1038/s41393-024-01036-y
  37. Pabon MA, Vaduganathan M, Claggett BL, Chatur S, Siqueira S, Marti-Castellote P, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN  et al.  In-hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial.  Eur J Heart Fail  2024 Dec;26(12):2532-2540. doi:10.1002/ejhf.3410
  38. Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J  et al.  Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes.  Nat Med  2024 Dec;30(12):3758-3764. doi:10.1038/s41591-024-03264-4
  39. Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N  et al.  Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.  ESC Heart Fail  2024 Dec;11(6):4427-4431. doi:10.1002/ehf2.14983
  40. Cicek V, Cikirikci EHK, Babaoğlu M, Erdem A, Tur Y, Mohamed MI, Cinar T, Savas H, Bagci U  Machine learning for prognostic prediction in coronary artery disease with SPECT data: a systematic review and meta-analysis.  EJNMMI Res  2024 Nov 26;14(1):117. pii:117
  41. Karp JF, Brinton RD, Fournier JC, Harding L, Jha MK, Lenze EJ, Mathew SJ, Meltzer-Brody S, Mohr DC, Riva-Posse P  et al.  Difficult to Treat Depression: Focus on Approach, Algorithms, and Access.  J Clin Psychiatry  2024 Nov 25;85(4). pii:psprmdd2408ah
  42. Ostrominski JW, Højbjerg Lassen MC, Claggett BL, Miao ZM, Inzucchi SE, Docherty KF, Desai AS, Jhund PS, Køber L, Ponikowski P  et al.  Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease.  Eur Heart J  2024 Nov 21;. pii:ehae780
  43. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  medRxiv  2024 Nov 20;. pii:2024.11.19.24317559
  44. Stiles-Shields C, Reyes KM, Lakhtakia T, Smith SR, Barnas OE, Gray EL, Krause CJ, Kruzan KP, Kwasny MJ, Mir Z  et al.  A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial.  BMC Psychiatry  2024 Nov 19;24(1):828. pii:828
  45. Cai W, Liu X, Barajas S, Xiao S, Vemula S, Chen H, Yang Y, Bochers C, Henley D, Liu S  et al.  Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes.  Leukemia  2024 Nov 19;. doi:10.1038/s41375-024-02462-w
  46. Simon G, Moise N, Mohr DC  Management of Depression-Reply.  JAMA  2024 Nov 19;332(19):1674-1675. doi:10.1001/jama.2024.18405
  47. Hanafiah A, Geng Z, Liu T, Tai YT, Cai W, Wang Q, Christensen N, Liu Y, Yue F, Gao Z  PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation.  bioRxiv  2024 Nov 15;. pii:2024.11.13.623456
  48. Adler DA, Yang Y, Viranda T, Xu X, Mohr DC, VAN Meter AR, Tartaglia JC, Jacobson NC, Wang F, Estrin D  et al.  Beyond Detection: Towards Actionable Sensing Research in Clinical Mental Healthcare.  Proc ACM Interact Mob Wearable Ubiquitous Technol  2024 Nov;8(4). pii:160
  49. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB  et al.  Metabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction.  Circ Heart Fail  2024 Nov;17(11):e011980. doi:10.1161/CIRCHEARTFAILURE.124.011980
  50. Chimura M, Petrie MC, Schou M, Martinez FA, Henderson AD, Claggett BL, Desai AS, Kolkhof P, Viswanathan P, Lage A  et al.  Finerenone Improves Outcomes in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Irrespective of Age: A Prespecified Analysis of FINEARTS-HF.  Circ Heart Fail  2024 Nov;17(11):e012437. doi:10.1161/CIRCHEARTFAILURE.124.012437