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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Viswanathan P, Kolkhof P, Schloemer P, Amarante F, Lam CSP  et al.  Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial.  Lancet Diabetes Endocrinol  2025 Feb;13(2):107-118. doi:10.1016/S2213-8587(24)00309-7
  2. Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN  Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care.  Contemp Clin Trials Commun  2025 Feb;43:101413. pii:101413
  3. Peterson TE, Lima JAC, Shah SJ, Bluemke DA, Bertoni AG, Liu Y, Ngo D, Varadarajan V, Mychaleckyj JC, Johnson CW  et al.  Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis.  ESC Heart Fail  2025 Feb;12(1):239-249. doi:10.1002/ehf2.15073
  4. Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM  et al.  Triaging mammography with artificial intelligence: an implementation study.  Breast Cancer Res Treat  2025 Jan 29;. doi:10.1007/s10549-025-07616-7
  5. Koh J, Caron S, Watters AN, Vaidyanathan M, Melnick D, Santi A, Hudson K, Arguelles C, Mathur P, Etemadi M  Technological Adjuncts to Streamline Patient Recruitment, Informed Consent, and Data Management Processes in Clinical Research: Observational Study.  JMIR Form Res  2025 Jan 29;9:e58628. doi:10.2196/58628
  6. Gerratana L, Davis AA, Foffano L, Reduzzi C, Rossi T, Medford A, Clifton K, Shah AN, Bucheit L, Velimirovic M  et al.  Integrating machine learning-predicted circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in metastatic breast cancer: A proof of principle study on endocrine resistance profiling.  Cancer Lett  2025 Jan 28;609:217325. doi:10.1016/j.canlet.2024.217325
  7. Li EV, Ren Y, Griffin J, Han C, Yamashita R, Mitani A, Zhou R, Huang HC, Yang X, Feng FY  et al.  An AI-Digital Pathology Algorithm Predicts Survival after Radical Prostatectomy from the PLCO Trial.  J Urol  2025 Jan 22;:101097JU0000000000004435. doi:10.1097/JU.0000000000004435
  8. Butt JH, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Viswanathan P, Lage A, Scheerer MF, Lam CSP  et al.  Finerenone, Obesity, and Heart Failure With Mildly Reduced/Preserved Ejection Fraction: Prespecified Analysis of FINEARTS-HF.  J Am Coll Cardiol  2025 Jan 21;85(2):140-155. doi:10.1016/j.jacc.2024.10.111
  9. Yang M, Henderson AD, Talebi A, Atherton JJ, Chiang CE, Chopra V, Comin-Colet J, Kosiborod MN, Kerr Saraiva JF, Claggett BL  et al.  Effect of Finerenone on the KCCQ in Patients With HFmrEF/HFpEF: A Prespecified Analysis of FINEARTS-HF.  J Am Coll Cardiol  2025 Jan 21;85(2):120-136. doi:10.1016/j.jacc.2024.09.023
  10. Mc Causland FR, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Brinker M, Perkins R, Scheerer MF  et al.  Finerenone and Kidney Outcomes in Patients With Heart Failure: The FINEARTS-HF Trial.  J Am Coll Cardiol  2025 Jan 21;85(2):159-168. doi:10.1016/j.jacc.2024.10.091
  11. Desai AS, Vaduganathan M, Claggett BL, Kulac IJ, Jhund PS, Cunningham J, Borentain M, Lay-Flurrie J, Viswanathan P, Rohwedder K  et al.  Finerenone in Patients With a Recent Worsening Heart Failure Event: The FINEARTS-HF Trial.  J Am Coll Cardiol  2025 Jan 21;85(2):106-116. doi:10.1016/j.jacc.2024.09.004
  12. Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B  et al.  Time to Significant Benefit of Finerenone in Patients With Heart Failure.  J Am Coll Cardiol  2025 Jan 21;85(2):199-202. doi:10.1016/j.jacc.2024.09.018
  13. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S  et al.  Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial.  Lancet Diabetes Endocrinol  2025 Jan 20;. pii:S2213-8587(24)00304-8
  14. Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H  NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High- Resolution Short Echo Time MR Spectroscopy Datasets.  Radiol Artif Intell  2025 Jan 15;:e230579. doi:10.1148/ryai.230579
  15. Vaduganathan M, Claggett BL, Kulac IJ, Miao ZM, Desai AS, Jhund PS, Henderson AD, Brinker M, Lay-Flurrie J, Viswanathan P  et al.  Effects of the Nonsteroidal MRA Finerenone With and Without Concomitant SGLT2 Inhibitor Use in Heart Failure.  Circulation  2025 Jan 14;151(2):149-158. doi:10.1161/CIRCULATIONAHA.124.072055
  16. Lei Y, Li Z, Bui Q, DePaul O, Nicol GE, Mohr DC, Fong MWM, Metts CL, Lee SI, Tomazin SE  et al.  Satisfaction, user experiences, and initial efficacy of a technology-supported self-management intervention (iSMART) to improve post-stroke functioning: a remoted randomized controlled trial.  Top Stroke Rehabil  2025 Jan 10;:1-15. doi:10.1080/10749357.2025.2450950
  17. Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB  et al.  Micropillar-induced changes in cell nucleus morphology enhance bone regeneration by modulating the secretome.  Res Sq  2025 Jan 07;. pii:rs.3.rs-5530535
  18. Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ  Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma.  PLoS One  2025;20(1):e0312415. pii:e0312415
  19. Docherty KF, Henderson AD, Jhund PS, Claggett BL, Desai AS, Mueller K, Viswanathan P, Scalise A, Lam CSP, Senni M  et al.  Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial.  Circulation  2025 Jan 07;151(1):45-58. doi:10.1161/CIRCULATIONAHA.124.072011
  20. Jakubek YA, Ma X, Stilp AM, Yu F, Bacon J, Wong JW, Aguet F, Ardlie K, Arnett DK, Barnes K  et al.  Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.  Am J Hum Genet  2025 Jan 06;. pii:S0002-9297(24)00456-7
  21. Liebovitz DM  Navigating Uncertainty in Digital Health Education.  JAMA Netw Open  2025 Jan 02;8(1):e2453095. doi:10.1001/jamanetworkopen.2024.53095
  22. Swaroop A, Yue F  Chromatin hubs drive key regulatory networks in leukemia.  Mol Cell  2025 Jan 02;85(1):1-2. doi:10.1016/j.molcel.2024.12.011
  23. Stiles-Shields C, Reyes KM, Lakhtakia T, Smith SR, Barnas OE, Gray EL, Krause CJ, Kruzan KP, Kwasny MJ, Mir Z  et al.  Correction: A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial.  BMC Psychiatry  2025 Jan 02;25(1):4. pii:4
  24. Idnay B, Xu Z, Adams WG, Adibuzzaman M, Anderson NR, Bahroos N, Bell DS, Bumgardner C, Campion T, Castro M  et al.  Environment scan of generative AI infrastructure for clinical and translational science.  Npj Health Syst  2025;2(1):4. pii:4
  25. Ragon B, Seymour A, Whipple EC, Surkis A, Haberstroh A, Muilenburg J, Rethlefsen ML, Aspinall EE, Deaver J, Dexter N  et al.  The role of information science within the clinical translational science ecosystem.  J Clin Transl Sci  2025;8(1):e224. pii:e224
  26. Vardeny O, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.  JAMA Cardiol  2025 Jan 01;10(1):42-48. pii:e244539
  27. Nargesi AA, Adejumo P, Dhingra LS, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN  et al.  Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing.  JACC Heart Fail  2025 Jan;13(1):75-87. doi:10.1016/j.jchf.2024.08.012
  28. Sadeghpour A, Jiang Z, Hummel YM, Frost M, Lam CSP, Shah SJ, Lund LH, Stone GW, Swaminathan M, Weissman NJ  et al.  An Automated Machine Learning-Based Quantitative Multiparametric Approach for Mitral Regurgitation Severity Grading.  JACC Cardiovasc Imaging  2025 Jan;18(1):1-12. doi:10.1016/j.jcmg.2024.06.011
  29. Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y  et al.  Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.  Hypertension  2025 Jan;82(1):36-45. doi:10.1161/HYPERTENSIONAHA.124.22095
  30. Naved BA, Luo Y  Contrasting rule and machine learning based digital self triage systems in the USA.  NPJ Digit Med  2024 Dec 27;7(1):381. pii:381
  31. Gould A, Luan Y, Hou Y, Korobova FV, Chen L, Arrieta VA, Amidei C, Ward R, Gomez C, Castro B  et al.  Endothelial Response to Blood-Brain Barrier Disruption in the Human Brain.  JCI Insight  2024 Dec 26;. pii:e187328
  32. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2024 Dec 24;. doi:10.1002/ehf2.15184
  33. Seyithanoglu D, Durak G, Keles E, Medetalibeyoglu A, Hong Z, Zhang Z, Taktak YB, Cebeci T, Tiwari P, Velichko YS  et al.  Advances for Managing Pancreatic Cystic Lesions: Integrating Imaging and AI Innovations.  Cancers (Basel)  2024 Dec 22;16(24). pii:4268
  34. Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP  et al.  Interleukin 8-CXCR2-mediated neutrophil extracellular trap formation in biliary atresia associated with neutrophil extracellular trap-induced stellate cell activation.  Hepatology  2024 Dec 18;. doi:10.1097/HEP.0000000000001195
  35. Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C  et al.  Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.  JAMA Cardiol  2024 Dec 18;. doi:10.1001/jamacardio.2024.4417
  36. Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B  et al.  Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.  Res Sq  2024 Dec 16;. pii:rs.3.rs-5487737
  37. Shin J, Luo Y  Relationship between exposure to multiple heavy metals and depressive symptoms in the US: The impact of alcohol consumption.  Heliyon  2024 Dec 15;10(23):e40221. pii:e40221
  38. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2024 Dec 11;. doi:10.1007/s11606-024-09159-x
  39. Stefanopoulos L, Kim BW, Sheppard J, Azcona EA, Vike NL, Bari S, Lalvani S, Woodward S, Maglaveras N, Block M  et al.  Discrete, recurrent, and scalable patterns in non-operant judgement underlie affective picture ratings.  Cogn Process  2024 Dec 07;. doi:10.1007/s10339-024-01250-9
  40. Quiriarte H, Noland RC, Stampley JE, Davis G, Li Z, Cho E, Kim Y, Doiron J, Spielmann G, Ghosh S  et al.  Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF.  JACC Basic Transl Sci  2024 Dec;9(12):1409-1425. doi:10.1016/j.jacbts.2024.07.009
  41. Wang MC, Awoyemi T, Allen NB, Shah R, Nayor M, Luo Y, Lima JAC, Lloyd-Jones DM, Khan SS  Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study.  Am J Prev Cardiol  2024 Dec;20:100889. pii:100889
  42. Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J  et al.  Author Correction: Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes.  Nat Med  2024 Dec;30(12):3778. doi:10.1038/s41591-024-03372-1
  43. Fudim M, Borlaug BA, Mohan RC, Price MJ, Fail P, Goyal P, Hummel SL, Zirakashvili T, Shaburishvili T, Patel RB  et al.  Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial.  JAMA Cardiol  2024 Dec 01;9(12):1143-1153. doi:10.1001/jamacardio.2024.2612
  44. Haynes G, Muhammad F, Weber KA, Khan AF, Hameed S, Shakir H, Van Hal M, Dickson D, Rohan M, Dhaher Y  et al.  Tract-specific magnetization transfer ratio provides insights into the severity of degenerative cervical myelopathy.  Spinal Cord  2024 Dec;62(12):700-707. doi:10.1038/s41393-024-01036-y
  45. Pabon MA, Vaduganathan M, Claggett BL, Chatur S, Siqueira S, Marti-Castellote P, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN  et al.  In-hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial.  Eur J Heart Fail  2024 Dec;26(12):2532-2540. doi:10.1002/ejhf.3410
  46. Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J  et al.  Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes.  Nat Med  2024 Dec;30(12):3758-3764. doi:10.1038/s41591-024-03264-4
  47. Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N  et al.  Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.  ESC Heart Fail  2024 Dec;11(6):4427-4431. doi:10.1002/ehf2.14983
  48. Cicek V, Cikirikci EHK, Babaoğlu M, Erdem A, Tur Y, Mohamed MI, Cinar T, Savas H, Bagci U  Machine learning for prognostic prediction in coronary artery disease with SPECT data: a systematic review and meta-analysis.  EJNMMI Res  2024 Nov 26;14(1):117. pii:117
  49. Karp JF, Brinton RD, Fournier JC, Harding L, Jha MK, Lenze EJ, Mathew SJ, Meltzer-Brody S, Mohr DC, Riva-Posse P  et al.  Difficult to Treat Depression: Focus on Approach, Algorithms, and Access.  J Clin Psychiatry  2024 Nov 25;85(4). pii:psprmdd2408ah
  50. Ostrominski JW, Højbjerg Lassen MC, Claggett BL, Miao ZM, Inzucchi SE, Docherty KF, Desai AS, Jhund PS, Køber L, Ponikowski P  et al.  Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease.  Eur Heart J  2024 Nov 21;. pii:ehae780